NOS
Nitric oxide synthase (NOS) is an enzyme responsible for the production of nitric oxide (NO), a signaling molecule involved in vasodilation, neurotransmission, and immune responses. There are three isoforms of NOS: neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), each playing distinct roles in physiological and pathological processes. Dysregulation of NOS activity is implicated in cardiovascular diseases, neurodegeneration, and inflammatory conditions. At CymitQuimica, we offer a selection of NOS modulators to support your research in vascular biology, neurobiology, and immunology.
Products of "NOS"
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Kuwanon A
CAS:Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.Formula:C25H24O6Purity:99.96%Color and Shape:SolidMolecular weight:420.45S-Methylisothiourea sulfate
CAS:S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septicFormula:C2H6N2SH2O4SPurity:99.58%Color and Shape:SolidMolecular weight:139.18Avanafil
CAS:Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Formula:C23H26ClN7O3Purity:98% - 99.03%Color and Shape:White SolidMolecular weight:483.95Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formula:C20H33N3O4·HClColor and Shape:White Crystalline SolidMolecular weight:415.96GW274150
CAS:GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.Formula:C8H17N3O2SPurity:96.43%Color and Shape:SolidMolecular weight:219.3Hydrangenol
CAS:Hydrangenol, from Hydrangea serrata leaves, is an anti-wrinkle agent. It reduces MMP, inflammation, boosts moisture and antioxidants.Formula:C15H12O4Purity:99.02% - 99.33%Color and Shape:SolidMolecular weight:256.25Ref: TM-TN4234
1mg137.00€5mg304.00€10mg455.00€25mg745.00€50mg1,026.00€100mg1,406.00€500mg2,812.00€1mL*10mM (DMSO)314.00€L-NAME hydrochloride
CAS:L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) ,Formula:C7H15N5O4·HClPurity:98.71% - ≥98%Color and Shape:White To Off-White PowderMolecular weight:269.69ODN 1826
CAS:ODN 1826 is a TLR9 agonist and immunostimulant, which has antitumor effects and promotes cell apoptosis.Purity:90% - 90%Color and Shape:SolidMolecular weight:6364.1S-MTC
CAS:S-MTC is a selective inhibitor of type I nitric oxide synthase.Formula:C7H15N3O2SPurity:98%Color and Shape:Off-White Powder / White SolidMolecular weight:205.28Flavone
CAS:Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.Formula:C15H10O2Purity:99.46% - 99.99%Color and Shape:SolidMolecular weight:222.2426-Deoxyactein
CAS:23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affectingFormula:C37H56O10Purity:98.06%Color and Shape:SolidMolecular weight:660.832-Iminobiotin
CAS:2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).Formula:C10H17N3O2SPurity:98%Color and Shape:SolidMolecular weight:243.33Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Formula:C24H30O11Purity:100% - ≥95%Color and Shape:White To Off-White PowderMolecular weight:494.49anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purity:99.06% - 99.81%Color and Shape:SolidMolecular weight:903.06Stylopine hydrochloride
CAS:Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.Formula:C19H18ClNO4Purity:99.04%Color and Shape:SolidMolecular weight:359.8L-NIO dihydrochloride
CAS:L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formula:C7H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:209.67Neotuberostemonine
CAS:Neotuberostemonine, an antitussive from Stemona tuberosa, mitigates BLM-induced lung fibrosis by inhibiting macrophages.Formula:C22H33NO4Purity:99.91%Color and Shape:SolidMolecular weight:375.5Ref: TM-T4953
1mg51.00€5mg210.00€10mg311.00€25mg525.00€50mg750.00€100mg1,017.00€1mL*10mM (DMSO)172.00€Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32Ref: TM-T5688
1mg47.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)131.00€Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Formula:C22H28O11Purity:98.57% - 99.92%Color and Shape:SolidMolecular weight:468.45ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21
