CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Products of "CXCR"
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Pentixafor
CAS:Pentixafor is a peptide that selectively targets the CXCR4 receptor and can be labeled with Gallium-68 (68Ga) for visualization using positron emissionFormula:C60H80N14O14Purity:98%Color and Shape:SolidMolecular weight:1221.36ITIC-4F
CAS:ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem setups.Formula:C94H78F4N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1499.92Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purity:98% - 98.63%Color and Shape:SolidMolecular weight:397.42Ref: TM-T7130
1mg40.00€5mg85.00€10mg120.00€25mg210.00€50mg316.00€100mg467.00€500mg1,026.00€1mL*10mM (DMSO)93.00€rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purity:97.85%Color and Shape:SolidMolecular weight:605.58SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurity:98.19% - 99.57%Color and Shape:SolidMolecular weight:467.2SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purity:98.16% - 98.79%Color and Shape:SolidMolecular weight:352.14Ref: TM-T1955
5mg50.00€10mg66.00€25mg127.00€50mg225.00€100mg404.00€200mg617.00€500mg938.00€1mL*10mM (DMSO)52.00€Reparixin L-lysine salt
CAS:Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.Formula:C20H35N3O5SPurity:99%Color and Shape:SolidMolecular weight:429.57EMU-116
CAS:EMU-116 is an orally active antagonist of CXCR4, utilized in cancer research.Formula:C25H35N5Color and Shape:SolidMolecular weight:405.58CXCR4-IN-1
CAS:CXCR4-IN-1 (Example C5), with an IC50 of 20 nM, is a potent inhibitor of CXCR4, applicable for the research of various conditions such as cancer, HIV, diabeticFormula:C23H32N6Purity:98%Color and Shape:SolidMolecular weight:392.54VUF-11222
CAS:VUF-11222 is an agonist of high affinity non-peptide CXCR3 agonist (pKi = 7.2).Formula:C25H31BrINPurity:99.82%Color and Shape:SolidMolecular weight:552.33Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purity:100% - 97.22%Color and Shape:SolidMolecular weight:328.36Ref: TM-T3S1416
1mg43.00€5mg88.00€10mg119.00€25mg259.00€50mg462.00€100mg662.00€500mg1,359.00€1mL*10mM (DMSO)87.00€CXCR4-IN-2
CXCR4-IN-2 (compound A1), a potent bifunctional fluorinated small molecule, inhibits CXCR4 and exhibits anticancer properties by exerting cytotoxicity (IC 50:Formula:C21H20F6N4SPurity:98%Color and Shape:SolidMolecular weight:474.47ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Formula:C94H82N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1427.96Elubrixin
CAS:Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).Formula:C17H17Cl2FN4O4SPurity:100.00% - 98.65%Color and Shape:SolidMolecular weight:463.31Ref: TM-T11179
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)266.00€NUCC-390 dihydrochloride (1060524-97-1 free base)
NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.Formula:C23H35Cl2N5OPurity:98%Color and Shape:SolidMolecular weight:468.46AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purity:99.39%Color and Shape:SolidMolecular weight:896.07Baohuoside I
CAS:Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.Formula:C27H30O10Purity:97.02% - 98.85%Color and Shape:SolidMolecular weight:514.52Ref: TM-T3396
2mg46.00€5mg66.00€10mg97.00€25mg180.00€50mg283.00€100mg472.00€200mg658.00€1mL*10mM (DMSO)130.00€CXCL-CXCR1/2-IN-1
CAS:CXCL-CXCR1/2-IN-1 is an ELR+CXCL-CXCR1/2 pathway inhibitor with anticancer activity and can be used in the study of cardiovascular disease.Formula:C14H8Cl2N4O3SPurity:99.40%Color and Shape:SoildMolecular weight:383.21
