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JAK/STAT signaling

JAK/STAT signaling

JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.

Subcategories of "JAK/STAT signaling"

Products of "JAK/STAT signaling"

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products per page.Found 187 products on this category.
  • WHI-P154

    CAS:
    WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
    Formula:C16H14BrN3O3
    Purity:98% - 99.6%
    Color and Shape:Solid
    Molecular weight:376.2

    Ref: TM-T1985

    2mg
    42.00€
    5mg
    62.00€
    10mg
    96.00€
    25mg
    175.00€
    50mg
    331.00€
    100mg
    538.00€
    1mL*10mM (DMSO)
    64.00€
  • TCS PIM-1 1

    CAS:
    TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.
    Formula:C18H11BrN2O2
    Purity:97% - 99.64%
    Color and Shape:Solid
    Molecular weight:367.2

    Ref: TM-T2253

    1mg
    35.00€
    5mg
    64.00€
    10mg
    88.00€
    25mg
    187.00€
    50mg
    284.00€
    100mg
    424.00€
    200mg
    612.00€
    1mL*10mM (DMSO)
    97.00€
  • PIM1-IN-1

    CAS:
    PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.
    Formula:C25H30N8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:474.56

    Ref: TM-T12474

    25mg
    1,084.00€
    50mg
    1,415.00€
    100mg
    2,242.00€
  • PIM-IN-2

    CAS:
    PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM .
    Formula:C19H22N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.4

    Ref: TM-T81460

    5mg
    To inquire
    50mg
    To inquire
  • JDTic dihydrochloride

    CAS:
    JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced by the κ-agonist U50, 488.
    Formula:C28H41Cl2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.55

    Ref: TM-T11721L

    2mg
    104.00€
    25mg
    635.00€
    50mg
    825.00€
    100mg
    1,225.00€
  • HS94

    CAS:
    HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value of 126 nM for Pim kinase inhibition and can be used to study hypertension.
    Formula:C15H15N5O2S
    Purity:95.04%
    Color and Shape:Solid
    Molecular weight:329.38

    Ref: TM-T77777

    1mg
    40.00€
    5mg
    86.00€
    10mg
    117.00€
    25mg
    227.00€
    50mg
    338.00€
    100mg
    500.00€
    500mg
    1,074.00€
  • Oclacitinib maleate

    CAS:
    Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.
    Formula:C15H23N5O2S·C4H4O4
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:453.51

    Ref: TM-T6914

    1mg
    39.00€
    2mg
    50.00€
    5mg
    79.00€
    10mg
    99.00€
    25mg
    170.00€
    50mg
    271.00€
    100mg
    457.00€
    1mL*10mM (DMSO)
    86.00€