
JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
Subcategories of "JAK/STAT signaling"
Products of "JAK/STAT signaling"
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WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.6%Color and Shape:SolidMolecular weight:376.2TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purity:97% - 99.64%Color and Shape:SolidMolecular weight:367.2Ref: TM-T2253
1mg35.00€5mg64.00€10mg88.00€25mg187.00€50mg284.00€100mg424.00€200mg612.00€1mL*10mM (DMSO)97.00€PIM1-IN-1
CAS:PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.Formula:C25H30N8O2Purity:98%Color and Shape:SolidMolecular weight:474.56PIM-IN-2
CAS:PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM .Formula:C19H22N4O2Purity:98%Color and Shape:SolidMolecular weight:338.4JDTic dihydrochloride
CAS:JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced by the κ-agonist U50, 488.Formula:C28H41Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:538.55HS94
CAS:HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value of 126 nM for Pim kinase inhibition and can be used to study hypertension.Formula:C15H15N5O2SPurity:95.04%Color and Shape:SolidMolecular weight:329.38Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purity:99.17%Color and Shape:SolidMolecular weight:453.51Ref: TM-T6914
1mg39.00€2mg50.00€5mg79.00€10mg99.00€25mg170.00€50mg271.00€100mg457.00€1mL*10mM (DMSO)86.00€