JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
Products of "JAK"
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JAK-IN-26
CAS:JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency inFormula:C22H24N6O3Purity:98%Color and Shape:SolidMolecular weight:420.46QL-1200186
CAS:QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production followingFormula:C26H27N7O3Purity:98%Color and Shape:SolidMolecular weight:485.54JAK3i
CAS:JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.Formula:C18H15FN4O3Purity:98.61% - 99.81%Color and Shape:SolidMolecular weight:354.34Solcitinib
CAS:Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.Formula:C22H23N5O2Purity:99.61% - 99.82%Color and Shape:SolidMolecular weight:389.45JAK-IN-29
JAK-IN-29 (Compound 3) is a potent inhibitor of Janus kinases (JAK) [1].Formula:C17H14ClN5O2Purity:98%Color and Shape:SolidMolecular weight:355.78JAK3/BTK-IN-1
CAS:JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two importantFormula:C25H28N8OPurity:97.89%Color and Shape:SolidMolecular weight:456.54Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:100% - 99.91%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g615.00€5mg52.00€10mg65.00€25mg82.00€50mg97.00€100mg145.00€200mg227.00€500mg418.00€1mL*10mM (DMSO)59.00€AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 98.51%Color and Shape:SolidMolecular weight:354.36Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purity:100% - 99.43%Color and Shape:SolidMolecular weight:425.46Ref: TM-T14687
1mg70.00€5mg153.00€10mg274.00€25mg432.00€50mg638.00€100mg908.00€200mg1,225.00€500mg1,825.00€1mL*10mM (DMSO)166.00€(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide；AG 490
CAS:Formula:C17H14N2O3Purity:98%Color and Shape:SolidMolecular weight:294.3047GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:98.54%Color and Shape:SolidMolecular weight:612.03Ref: TM-T9826
1mg87.00€5mg192.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)259.00€
