cAMP
cAMP is a second messenger important in many biological processes, including the regulation of metabolism, gene expression, and cell growth. In the MAPK signaling pathway, cAMP can modulate the activity of various kinases, including PKA, which in turn influences the MAPK cascade. Dysregulation of cAMP signaling is implicated in various diseases, including cancer and cardiovascular disorders. At CymitQuimica, we offer a variety of cAMP modulators to support your research in signal transduction, metabolism, and disease pathology.
Products of "cAMP"
Sort by
Found 58 products on this category.
JNJ-39758979
CAS:JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).Formula:C11H19N5Purity:98.3% - 99.62%Color and Shape:SolidMolecular weight:221.3Ref: TM-T11723L
1mg74.00€5mg160.00€10mg250.00€25mg424.00€50mg615.00€100mg905.00€1mL*10mM (DMSO)170.00€GLP-1R modulator L7-028
CAS:GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.Formula:C24H28N2O3Purity:98.76% - 99.49%Color and Shape:SolidMolecular weight:392.49OX04528
CAS:OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.Formula:C16H13F6NO2Purity:99.74%Color and Shape:SoildMolecular weight:365.27HJC0197
CAS:HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.Formula:C19H21N3OSPurity:98.05%Color and Shape:SolidMolecular weight:339.45Ref: TM-T15485
2mg38.00€5mg54.00€10mg86.00€25mg135.00€50mg188.00€100mg283.00€200mg426.00€1mL*10mM (DMSO)64.00€Glaucine
CAS:Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.Formula:C21H25NO4Purity:99.14% - 99.42%Color and Shape:SolidMolecular weight:355.43PSN 375963
CAS:PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.Formula:C17H23N3OPurity:99.24%Color and Shape:SolidMolecular weight:285.38Ref: TM-T23204
5mg46.00€10mg65.00€25mg116.00€50mg187.00€100mg306.00€200mg437.00€1mL*10mM (DMSO)64.00€MRE3008F20
CAS:MRE3008F20 is an AA3R antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used to study glaucoma and asthma.Formula:C21H20N8O3Purity:97.66%Color and Shape:SolidMolecular weight:432.44Dodoviscin A
CAS:Dodoviscin A: a potential agent for altering pigmentation, inhibits melanin synthesis; also promotes fat cell differentiation and gene upregulation.Formula:C27H32O9Purity:98%Color and Shape:SolidMolecular weight:500.544Atherosperminine
CAS:Atherosperminine inhibits AChE/BChE and relaxes trachealis via cAMP phosphodiesterase inhibition.Formula:C20H23NO2Purity:99.4%Color and Shape:SolidMolecular weight:309.4Cyclic AMP
CAS:cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.Formula:C10H12N5O6PPurity:100% - 99.93%Color and Shape:SolidMolecular weight:329.21ESI-09
CAS:ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.Formula:C16H15ClN4O2Purity:97.24% - 99.57%Color and Shape:SolidMolecular weight:330.77ESI-05
CAS:ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.Formula:C16H18O2SPurity:98.00%Color and Shape:SolidMolecular weight:274.38Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Formula:C24H19FN2O3Purity:99.16%Color and Shape:SolidMolecular weight:402.42NCGC00229600
CAS:NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.Formula:C30H29N3O3Purity:99.27%Color and Shape:SolidMolecular weight:479.57Ref: TM-T12192
1mg64.00€5mg145.00€10mg212.00€25mg373.00€50mg562.00€100mg848.00€200mg1,121.00€1mL*10mM (DMSO)153.00€Adenosine receptor A1 antagonist 5
CAS:1,3-Dipropyl-8-phenylxanthine is an adenosine antagonist, oxypurine, insecticide, and reduces high blood pressure.Formula:C17H20N4O2Purity:100%Color and Shape:SolidMolecular weight:312.37MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Formula:C19H16Cl3FN4OPurity:98.09% - 98.94%Color and Shape:SolidMolecular weight:441.71Ref: TM-T12103
1mg145.00€2mg207.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€500mg3,125.00€1mL*10mM (DMSO)378.00€(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purity:99.14%Color and Shape:SolidMolecular weight:275.34UNC0006
CAS:UNC0006 is a β-arrestin-biased dopamine D2 ligand.Formula:C24H29Cl2N3O2Purity:98.48% - 99.83%Color and Shape:SolidMolecular weight:462.41Ro 20-1724
CAS:Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Formula:C15H22N2O3Purity:98% - 99.14%Color and Shape:SolidMolecular weight:278.35Panaxydol
CAS:Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38Formula:C17H24O2Purity:98%Color and Shape:SolidMolecular weight:260.37Torbafylline
CAS:Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.Formula:C16H26N4O4Purity:98% - 99%Color and Shape:SoildMolecular weight:338.4Ref: TM-T67965
1mg128.00€5mg304.00€10mg457.00€25mg747.00€50mg1,026.00€100mg1,406.00€500mg2,812.00€1mL*10mM (DMSO)314.00€BC 11-38
CAS:BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Formula:C15H16N2OS2Purity:97.71% - 98.72%Color and Shape:SolidMolecular weight:304.43Ref: TM-T21865
1mg35.00€5mg70.00€10mg97.00€25mg202.00€50mg329.00€100mg527.00€200mg747.00€1mL*10mM (DMSO)81.00€I942
CAS:I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilicalFormula:C20H19NO4SPurity:99.75%Color and Shape:SolidMolecular weight:369.43Catalpalactone
CAS:Catalpalactone: antitermitic, cytotoxic, inhibits NO in cells (IC50 9.80µM), reduces dopamine synthesis, hinders TPA-induced EBV-EA activation.Formula:C15H14O4Purity:98%Color and Shape:SolidMolecular weight:258.27RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFormula:C19H14ClN5O4Purity:99.25%Color and Shape:SolidMolecular weight:411.8Ref: TM-T23256
2mg34.00€5mg52.00€10mg85.00€25mg170.00€50mg259.00€100mg374.00€200mg545.00€1mL*10mM (DMSO)65.00€Rp-cAMPS sodium
CAS:Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.Formula:C10H11N5NaO5PSPurity:99.71%Color and Shape:SolidMolecular weight:367.250990CL
CAS:0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMPFormula:C21H21N5Purity:98.86%Color and Shape:SolidMolecular weight:343.42Ref: TM-T13983
1mg202.00€5mg512.00€10mg740.00€25mg1,121.00€50mg1,539.00€100mg2,072.00€1mL*10mM (DMSO)535.00€LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.Formula:C43H46N2O5SPurity:98.8% - 99.33%Color and Shape:SolidMolecular weight:702.9Ref: TM-T11845
1mg88.00€5mg187.00€10mg274.00€25mg472.00€50mg692.00€100mg938.00€1mL*10mM (DMSO)283.00€GAT211
CAS:GAT211 (AZ-4) is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM) for the study of epilepsy.Formula:C22H18N2O2Purity:99.7%Color and Shape:SolidMolecular weight:342.39Ref: TM-T27405
1mg35.00€5mg70.00€10mg96.00€25mg157.00€50mg221.00€100mg328.00€500mg792.00€1mL*10mM (DMSO)78.00€LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Formula:C7H9NO6SPurity:99% - 99.16%Color and Shape:SolidMolecular weight:235.22MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Formula:C27H29N5O5Purity:97.95%Color and Shape:SolidMolecular weight:503.55Ref: TM-T16136
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg240.00€50mg472.00€100mg687.00€1mL*10mM (DMSO)88.00€KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Formula:C23H18N2O2Purity:98.03%Color and Shape:SolidMolecular weight:354.4Ref: TM-T9238
2mg38.00€5mg58.00€10mg90.00€25mg182.00€50mg279.00€100mg420.00€200mg592.00€1mL*10mM (DMSO)65.00€CB1R Allosteric modulator 3
CAS:CB1R Allosteric modulator 3 is a CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP, and can be used for the study of obesity and nicotine addiction.Formula:C22H17ClN2O2Purity:98.18%Color and Shape:SolidMolecular weight:376.84Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formula:C12H12N2O2SPurity:95.52%Color and Shape:SolidMolecular weight:248.3Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purity:98.83% - 99.86%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.5Ref: TM-T2939
5mg43.00€10mg56.00€25mg86.00€50mg96.00€100mg144.00€200mg182.00€500mg306.00€1mL*10mM (DMSO)56.00€Piclamilast
CAS:Piclamilast (RP 73401) is a PDE4 inhibitor.Formula:C18H18Cl2N2O3Purity:98.28%Color and Shape:SolidMolecular weight:381.25Fargesone B
CAS:Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.Formula:C21H24O6Purity:98%Color and Shape:SolidMolecular weight:372.417SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Formula:C15H13ClN4O2S2Purity:97.82% - 98%Color and Shape:SolidMolecular weight:380.87Ref: TM-T3183
1mg84.00€5mg160.00€10mg259.00€25mg419.00€50mg562.00€100mg775.00€200mg1,026.00€1mL*10mM (DMSO)170.00€TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Formula:C16H16ClN5Purity:97.77%Color and Shape:SoildMolecular weight:313.78Ref: TM-T64355
1mg42.00€5mg165.00€10mg235.00€25mg432.00€50mg648.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)177.00€TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Formula:C26H19F3N4OPurity:98.48%Color and Shape:SolidMolecular weight:460.45Ref: TM-T13189
1mg92.00€2mg120.00€5mg187.00€10mg279.00€25mg487.00€50mg705.00€100mg998.00€500mg1,882.00€1mL*10mM (DMSO)188.00€Kushenol A
CAS:Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity.Formula:C25H28O5Purity:98%Color and Shape:SolidMolecular weight:408.49Pinoresinol 4-O-β-D-glucopyranoside
CAS:(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.Formula:C26H32O11Purity:100% - 99.77%Color and Shape:SolidMolecular weight:520.53Ref: TM-T4S0792
1mg52.00€5mg101.00€10mg170.00€25mg279.00€50mg391.00€100mg552.00€200mg745.00€1mL*10mM (DMSO)134.00€Mirabegron
CAS:Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.Formula:C21H24N4O2SPurity:99.64%Color and Shape:Light Yellow To Yellow SolidMolecular weight:396.51Ref: TM-T1671
2mg38.00€5mg55.00€10mg93.00€25mg169.00€50mg264.00€100mg426.00€200mg617.00€1mL*10mM (DMSO)60.00€Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Formula:C18H23N5NaO8PPurity:96.56% - 99.76%Color and Shape:White PowderMolecular weight:491.37KH7
CAS:KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.Formula:C17H15BrN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:419.3Licoarylcoumarin
CAS:Licoarylcoumarin inhibits cAMP phosphodiesterase, fights VRE bacteria, has anti-HIV properties, and blocks xanthine oxidase.Formula:C21H20O6Purity:98%Color and Shape:SolidMolecular weight:368.38CJ-42794
CAS:CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).Formula:C22H17ClFNO4Purity:99.49%Color and Shape:SolidMolecular weight:413.83Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.Color and Shape:Lyophilized PowderMolecular weight:24.7 kDa (predicted)A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg35.00€5mg66.00€10mg96.00€25mg170.00€50mg274.00€100mg439.00€500mg938.00€1mL*10mM (DMSO)90.00€Bithionol
CAS:Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential toFormula:C12H6Cl4O2SPurity:99.04%Color and Shape:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Molecular weight:356.05ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurity:99.05%Color and Shape:SolidMolecular weight:353.48Vidupiprant
CAS:Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.Formula:C28H27Cl2FN2O6SPurity:97.16%Color and Shape:SolidMolecular weight:609.49Ref: TM-T17232
1mg66.00€5mg144.00€10mg217.00€25mg396.00€50mg590.00€100mg840.00€500mg1,691.00€1mL*10mM (DMSO)188.00€EPAC 5376753
CAS:EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.Formula:C15H8Cl2N2O3SPurity:97.48%Color and Shape:SolidMolecular weight:367.212-PCCA hydrochloride
CAS:2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with anFormula:C30H39Cl2N3OPurity:99.65% - 99.96%Color and Shape:SoildMolecular weight:528.56Ref: TM-T80666
1mg110.00€5mg264.00€10mg369.00€25mg593.00€50mg785.00€100mg1,074.00€200mg1,444.00€1mL*10mM (DMSO)306.00€7-Methoxyrosmanol
CAS:7-Methoxyrosmanol (7-O-Methylrosmanol) can suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters.Formula:C21H28O5Purity:98.4%Color and Shape:SolidMolecular weight:360.44HJC0350
CAS:HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.Formula:C15H19NO2SPurity:99.5% - 99.53%Color and Shape:SolidMolecular weight:277.38CE3F4
CAS:CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).Formula:C11H10Br2FNOPurity:97.15% - 98.06%Color and Shape:SolidMolecular weight:351.01Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Formula:C24H22N4O5SPurity:99.15% - 99.41%Color and Shape:SolidMolecular weight:478.52Ref: TM-T3174
1mg35.00€5mg65.00€10mg97.00€25mg188.00€50mg311.00€100mg449.00€200mg628.00€1mL*10mM (DMSO)70.00€
