MNK
MNKs are a group of kinases that interact with MAPKs, particularly ERK and p38, to regulate protein synthesis by phosphorylating the eukaryotic initiation factor 4E (eIF4E). MNK signaling plays a role in cellular stress responses, inflammation, and cancer progression. Targeting MNKs is an emerging strategy in cancer therapy and anti-inflammatory treatments. At CymitQuimica, we provide a selection of MNK inhibitors and modulators to support your research in protein synthesis regulation, oncology, and inflammation.
Products of "MNK"
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Found 8 products on this category.
SLV-2436
CAS:SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 nM).Formula:C19H15ClN4OPurity:98.56%Color and Shape:SolidMolecular weight:350.8Ref: TM-T4424
1mg81.00€2mg106.00€5mg170.00€10mg274.00€25mg523.00€50mg753.00€100mg1,035.00€1mL*10mM (DMSO)188.00€Tomivosertib
CAS:Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.Formula:C17H20N6O2Purity:97.34% - 99.67%Color and Shape:SolidMolecular weight:340.38Ref: TM-T3468
1mg49.00€5mg127.00€10mg188.00€25mg359.00€50mg565.00€100mg868.00€200mg1,169.00€1mL*10mM (DMSO)139.00€ETC-206
CAS:ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).Formula:C25H20N4O2Purity:99.72% - 99.79%Color and Shape:SolidMolecular weight:408.45Ref: TM-T15250
2mg35.00€5mg52.00€10mg96.00€25mg148.00€50mg226.00€100mg335.00€500mg730.00€1mL*10mM (DMSO)58.00€MNK1/2-IN-5
CAS:MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used to study solid tumors and hematological malignancies.Formula:C17H16N4O2Purity:98.04%Color and Shape:SolidMolecular weight:308.33CGP 57380
CAS:CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-likeFormula:C11H9FN6Purity:98.49%Color and Shape:SolidMolecular weight:244.23Ref: TM-T6440
1mg47.00€2mg62.00€5mg90.00€10mg142.00€25mg261.00€50mg435.00€100mg627.00€200mg877.00€1mL*10mM (DMSO)113.00€DS12881479
CAS:DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1].Formula:C16H19N3OSPurity:100%Color and Shape:SolidMolecular weight:301.41QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 activity that inhibits BTK, MNK1, and MNK2 kinases.Formula:C25H20ClN5O2Purity:98.89%Color and Shape:SoildMolecular weight:457.91HG-10-102-01
CAS:HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formula:C17H20ClN5O3Purity:99.59%Color and Shape:SolidMolecular weight:377.83Ref: TM-T7196
2mg38.00€5mg58.00€10mg94.00€25mg170.00€50mg264.00€100mg380.00€200mg540.00€1mL*10mM (DMSO)65.00€
