MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Products of "MAPK"
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ZINC12409120
CAS:ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23Formula:C20H16N4O2Purity:98.69% - 99.84%Color and Shape:SolidMolecular weight:344.37Ref: TM-T61122
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€KRAS inhibitor-38
CAS:KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.Formula:C53H68ClF2N9O8SColor and Shape:SolidMolecular weight:1064.68A-443654
CAS:A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formula:C24H23N5OPurity:97.73% - 98.04%Color and Shape:SolidMolecular weight:397.47Ref: TM-T14072
1mg92.00€5mg188.00€10mg305.00€25mg567.00€50mg868.00€100mg1,301.00€200mg1,758.00€500mg2,593.00€1mL*10mM (DMSO)215.00€BI-0474
CAS:BI-0474: KRASG12C inhibitor, IC50=7.0 nM, blocks GDP-KRAS/SOS1, anti-tumor in NCI-H358 cells & lung cancer model, for cancer research.Formula:C30H37N9O2SPurity:100%Color and Shape:SolidMolecular weight:587.74XMU-MP-9
CAS:XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.Formula:C19H13ClFN3OSColor and Shape:SolidMolecular weight:385.84CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39Ref: TM-T5393
1mg49.00€2mg65.00€5mg97.00€10mg160.00€25mg305.00€50mg472.00€100mg707.00€1mL*10mM (DMSO)106.00€β-Tocopherol
CAS:Beta-Tocopherol has effects on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).Cost-effective and quality-assured.Formula:C28H48O2Purity:99.8% - 99.92%Color and Shape:SolidMolecular weight:416.68KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Formula:C24H19ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:484.88Tizaterkib
CAS:Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.Formula:C24H24F2N8O2Purity:99.6% - 99.63%Color and Shape:SolidMolecular weight:494.5MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purity:97.18%Color and Shape:OilMolecular weight:508.65Ref: TM-T24437
1mg37.00€5mg97.00€10mg169.00€25mg291.00€50mg423.00€100mg562.00€500mg1,121.00€1mL*10mM (DMSO)108.00€Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.Formula:C71H114N16O28Purity:95.29%Color and Shape:SolidMolecular weight:1639.76Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurity:99.02% - ≥95%Color and Shape:SolidMolecular weight:436.26MS934
CAS:MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 μM.Formula:C52H69F3IN7O6SPurity:98%Color and Shape:SolidMolecular weight:1104.11Isorhamnetin 3-O-galactoside
CAS:Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic for treatment of severe vascular inflammatory diseases.Formula:C22H22O12Purity:98%Color and Shape:SolidMolecular weight:478.4MK2-IN-1 hydrochloride
CAS:MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.Formula:C27H26Cl2N4O2Purity:99.67%Color and Shape:SolidMolecular weight:509.436H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Ref: TM-T5494
1mg39.00€5mg96.00€10mg153.00€25mg305.00€50mg454.00€100mg655.00€500mg1,406.00€1mL*10mM (DMSO)114.00€GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurity:98.86%Color and Shape:SolidMolecular weight:337.36Ref: TM-T8605
1mg131.00€2mg188.00€5mg283.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€1mL*10mM (DMSO)298.00€NVP-BHG712
CAS:NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormula:C26H20F3N7OPurity:97.32%Color and Shape:SolidMolecular weight:503.48Ref: TM-T6348
1mg35.00€5mg79.00€10mg111.00€25mg212.00€50mg393.00€100mg587.00€200mg833.00€1mL*10mM (DMSO)88.00€Raf inhibitor 2
CAS:Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.Formula:C15H8Br2ClNO2Purity:98.53%Color and Shape:SolidMolecular weight:429.49Ref: TM-T4194
2mg40.00€5mg62.00€10mg96.00€25mg164.00€50mg240.00€100mg349.00€200mg492.00€1mL*10mM (DMSO)64.00€LY-2584702 free base
CAS:LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).Formula:C21H19F4N7Purity:98.04% - 98.72%Color and Shape:SolidMolecular weight:445.42Ref: TM-T6159
1mg47.00€2mg59.00€5mg114.00€10mg147.00€25mg315.00€50mg425.00€100mg625.00€500mg1,311.00€HPK1-IN-7
CAS:HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).Formula:C24H22N6O4Purity:99.31%Color and Shape:SolidMolecular weight:458.47Ref: TM-T9470
1mg85.00€5mg167.00€10mg275.00€25mg449.00€50mg615.00€100mg848.00€200mg1,121.00€1mL*10mM (DMSO)167.00€ERK1/2 inhibitor 1
CAS:ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.Formula:C29H32ClN5O4Purity:99.09%Color and Shape:SolidMolecular weight:550.05FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Color and Shape:Odour Solid12(S)-HETE
CAS:Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47SL 0101-1
CAS:SL0101: selective, reversible ATP-competitive RSK inhibitor, membrane-permeable, IC50=89nM, potent RSK1/2 inhibitor, Ki=1μM.Formula:C25H24O12Purity:98%Color and Shape:SolidMolecular weight:516.45GW 284543 hydrochloride
CAS:GW 284543 hydrochloride is a selective inhibitor of MEK5 .Formula:C23H21ClN2O3Purity:99.73%Color and Shape:SolidMolecular weight:408.87Nyasol
CAS:Nyasol has anti-allergy, anti-inflammatory, antifungal, and antiprotozoal properties with notable IC50 values against specific pathogens.Formula:C17H16O2Purity:98%Color and Shape:SolidMolecular weight:252.31SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurity:97.79%Color and Shape:SolidMolecular weight:413.9Raf inhibitor 1 dihydrochloride
CAS:Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.Formula:C26H19ClN8HClPurity:98.19% - 98.44%Color and Shape:SolidMolecular weight:551.86Ref: TM-T4167
1mg49.00€2mg64.00€5mg103.00€10mg180.00€25mg300.00€50mg445.00€100mg652.00€500mg1,378.00€1mL*10mM (DMSO)188.00€Rineterkib
CAS:Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.Formula:C26H27BrF3N5O2Purity:98.4%Color and Shape:SolidMolecular weight:578.42Ref: TM-T11224
1mg95.00€5mg188.00€10mg354.00€25mg597.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)249.00€Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFormula:C14H20N4OPurity:100% - 97.92%Color and Shape:SolidMolecular weight:260.33B-Raf IN 11
CAS:B-Raf IN 11 is a novel selective inhibitor.Formula:C17H14BrF2N3O3SPurity:99.46%Color and Shape:SolidMolecular weight:458.28KRAS G12C inhibitor 59
CAS:KRAS G12C Inhibitor 59 is a compound with anticancer properties.Formula:C32H39F6N7O5Purity:98%Color and Shape:SolidMolecular weight:715.69K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29Ref: TM-T5469
2mg46.00€5mg70.00€10mg101.00€25mg182.00€50mg284.00€100mg424.00€200mg588.00€1mL*10mM (DMSO)77.00€MNK1/2-IN-5
CAS:MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used to study solid tumors and hematological malignancies.Formula:C17H16N4O2Purity:98.04%Color and Shape:SolidMolecular weight:308.33KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purity:100% - 99.76%Color and Shape:SolidMolecular weight:425.42Ref: TM-T6130
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg208.00€50mg313.00€100mg465.00€1mL*10mM (DMSO)87.00€Luvometinib
CAS:Luvometinib is an inhibitor of the mitogen-activated protein kinase (MEK) with antitumor activity.Formula:C26H22F2IN5O4SColor and Shape:SolidMolecular weight:665.45LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formula:C25H25F3N4O4Purity:98.3% - 99.92%Color and Shape:SolidMolecular weight:502.49Ref: TM-T11898
1mg52.00€5mg122.00€10mg185.00€25mg363.00€50mg567.00€100mg690.00€200mg948.00€500mg1,444.00€1mL*10mM (DMSO)135.00€JNK-1-IN-4
CAS:JNK-1-IN-4 (Compound E1) is an inhibitor of JNK, targeting JNK-1, JNK-2, and JNK-3 with IC50 values of 2.7, 19.0, and 9.0 nM, respectively. This compound inhibits the phosphorylation of c-Jun and reduces the expression of TGF-β1-induced EMT markers (such as fibronectin and α-SMA). JNK-1-IN-4 exhibits favorable pharmacokinetic properties with a bioavailability of 69%. Additionally, it demonstrates antifibrotic effects in a Bleomycin-induced mouse model of idiopathic pulmonary fibrosis.Formula:C22H25BrN6O3Color and Shape:SolidMolecular weight:501.38Lucidenic acid F
CAS:Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.Formula:C27H36O6Purity:98%Color and Shape:SolidMolecular weight:456.57Ulixertinib hydrochloride
CAS:Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits the NB cell cycle and promotes apoptosisFormula:C21H23Cl3N4O2Purity:99.85%Color and Shape:SolidMolecular weight:469.79Fustin
CAS:Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes.Formula:C15H12O6Purity:98%Color and Shape:SolidMolecular weight:288.25PROTAC B-Raf degrader 1
CAS:PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.Formula:C36H37N5O12SPurity:98%Color and Shape:SolidMolecular weight:763.77LY-2584702 hydrochloride
CAS:Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.Formula:C21H20ClF4N7Purity:98%Color and Shape:SolidMolecular weight:481.88MEK-IN-6
CAS:MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, with an IC50 of 2 nM, making itFormula:C18H20FN3O4SPurity:98%Color and Shape:SolidMolecular weight:393.43VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purity:100% - 99%Color and Shape:SolidMolecular weight:404.32Emprumapimod
CAS:Emprumapimod, an oral p38α MAPK inhibitor, targets RPMI-8226 cells, curbs LPS-induced IL-6; IC50: 100 pM; for cardiomyopathy, acute pain.Formula:C24H29F2N5O3Purity:100% - 99.21%Color and Shape:SolidMolecular weight:473.52MAPK13-IN-1
CAS:MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formula:C20H23N5O2Purity:99.55%Color and Shape:SolidMolecular weight:365.43Ref: TM-T11943
1mg99.00€2mg144.00€5mg235.00€10mg354.00€25mg610.00€50mg885.00€100mg1,293.00€500mg2,585.00€1mL*10mM (DMSO)259.00€KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15DMX-5804
CAS:DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in miceFormula:C21H19N3O3Purity:99.34%Color and Shape:SolidMolecular weight:361.39Ref: TM-T5483
1mg106.00€2mg155.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)259.00€ARS-1323
CAS:ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.Formula:C21H17ClF2N4O2Purity:98.88%Color and Shape:SolidMolecular weight:430.84MAP4K4-IN-6
MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces the phosphorylation of c-Jun and exhibits neuroprotective effects. Additionally, MAP4K4-IN-6 enhances the vitality of motor neurons and can be utilized in the study of amyotrophic lateral sclerosis (ALS).Color and Shape:Odour SolidIM-54
CAS:IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.Formula:C19H23N3O2Purity:99.05%Color and Shape:SolidMolecular weight:325.4N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.69%Color and Shape:SolidMolecular weight:177.24STE-MEK1(13)
CAS:STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes the phosphorylation of ERK1/2, as demonstrated in studies [1Formula:C86H153N19O17SPurity:98%Color and Shape:SolidMolecular weight:1757.32IACS-13909
CAS:IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.Formula:C17H18Cl2N6Purity:98.80%Color and Shape:SolidMolecular weight:377.27JNK-IN-12
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptideFormula:C56H82N16O7Purity:98%Color and Shape:SolidMolecular weight:1091.35Haginin A
CAS:Haginin A inhibits hyperpigmentation and skin disorders, reduces tyrosinase/TRP-1, and has antioxidant properties.Formula:C17H16O5Purity:98%Color and Shape:SolidMolecular weight:300.31PLX7904
CAS:PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it in RAS mutants.Formula:C24H22F2N6O3SPurity:96.27% - 96.27%Color and Shape:SolidMolecular weight:512.53KRAS inhibitor-31
CAS:KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of 0.019 nM for KRas G12D, 0.019 nM for KRas G12C, and 0.096 nM for KRas G12V, illustrating its efficacy across these variants.Formula:C33H30F3N5O4Color and Shape:SolidMolecular weight:617.62RAS GTPase inhibitor 1
CAS:RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.Formula:C27H28ClF4N5O2Purity:99.66%Color and Shape:SolidMolecular weight:565.99HI-TOPK-032
CAS:HI-TOPK-032 is an effective and specific inhibitor of TOPK.Formula:C20H11N5OSPurity:98.52%Color and Shape:SolidMolecular weight:369.4ARS-1630
CAS:ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.Formula:C21H17ClF2N4O2Purity:97.81%Color and Shape:SolidMolecular weight:430.84Ref: TM-T10376
1mg52.00€5mg117.00€10mg170.00€25mg325.00€50mg469.00€100mg615.00€1mL*10mM (DMSO)134.00€BI-3406
CAS:BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formula:C23H25F3N4O3Purity:99.20% - 99.66%Color and Shape:SolidMolecular weight:462.46Ref: TM-T12979
1mg73.00€5mg160.00€10mg250.00€25mg464.00€50mg663.00€100mg919.00€500mg1,833.00€1mL*10mM (DMSO)170.00€L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurity:≥95%Color and Shape:SolidMolecular weight:347.8Ibetazol
Ibetazol is an inhibitor of importin β1 (KPNB1), which functions by binding to Cys585 of importin β1, thus preventing importin β1-mediated nuclear import with an EC50 of 6.1 µM.Formula:C13H11F3N2OSColor and Shape:SolidMolecular weight:300.3AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurity:98.35% - 98.9%Color and Shape:SolidMolecular weight:503.58Ref: TM-T6380
1mg52.00€5mg97.00€10mg166.00€25mg303.00€50mg467.00€100mg682.00€500mg1,415.00€1mL*10mM (DMSO)105.00€INS018 055
CAS:INS018 055 (TNIK&MAP4K4-IN-2) is a TNIK and MAP4K4 inhibitor with anti-fibrotic activity.Formula:C27H30FN7OPurity:98.53%Color and Shape:SolidMolecular weight:487.57MEK1/2-IN-3
MEK1/2-IN-3 (Compound M15) is an inhibitor of MEK1, with an IC50 value of 10.29 nM. It effectively suppresses tumor cell proliferation and migration, induces apoptosis, and exhibits good liver microsomal stability. MEK1/2-IN-3 is applicable in the study of solid tumors.Formula:C28H23F3IN3O4Color and Shape:SolidMolecular weight:649.4Griffipavixanthone
CAS:Griffipavixanthone blocks H520 lung cancer growth, induces apoptosis via mitochondria & ROS, halts esophageal cancer spread by targeting RAF pathway.Formula:C36H28O12Purity:98%Color and Shape:SolidMolecular weight:652.6JTP10-△-R9 TFA
JTP10-△-R9 TFA is a selective inhibitor of JNK2 peptide (IC50: 89 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.Formula:C119H214F3N53O26Purity:98%Color and Shape:SolidMolecular weight:2860.31Morelloflavone
CAS:Morelloflavone(Fukugetin) is an anticancer biflavonoid that inhibits tumor angiogenesis by targeting Rho GTPases and ERK signaling pathways.Formula:C30H20O11Color and Shape:SolidMolecular weight:556.47Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.Formula:C38H56N2O4Purity:98%Color and Shape:SolidMolecular weight:604.86VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formula:C24H20Cl2FN5O2Purity:98.92% - ≥98%Color and Shape:SolidMolecular weight:500.35XMD17-109
CAS:XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).Formula:C36H46N8O3Purity:98.86% - 99.75%Color and Shape:SolidMolecular weight:638.8Ref: TM-T1842
1mg42.00€2mg52.00€5mg87.00€10mg144.00€25mg221.00€50mg359.00€100mg538.00€1mL*10mM (DMSO)110.00€NSC-70220
CAS:SOS1-IN-1 is an inhibitor of SOS1.Formula:C22H15NO2Purity:98%Color and Shape:SolidMolecular weight:325.36
