MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Products of "MAPK"
Sort by
Binimetinib
CAS:Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formula:C17H15BrF2N4O3Purity:100% - 99%Color and Shape:SolidMolecular weight:441.23MC 976
CAS:MC 976 is a derivative of Vitamin D3.Formula:C27H42O3Purity:98%Color and Shape:SolidMolecular weight:414.63KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Formula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68Cimiside E
CAS:Cimiside E tamps inflammation, halts gastric cancer growth, and triggers cell death by modulating PPAR-γ, ERK1/2, PI3K, and PKC pathways.Formula:C35H54O8Purity:98%Color and Shape:SolidMolecular weight:602.809TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33Ref: TM-T4646
5mg39.00€10mg58.00€25mg104.00€50mg160.00€100mg244.00€500mgTo inquire1mL*10mM (DMSO)43.00€(S)-BAY-293
CAS:(S)-BAY-293 is a potent pan-KRAS inhibitor for the study of primary non-small lung and pancreatic cancers.Formula:C25H28N4O2SPurity:98%Color and Shape:SolidMolecular weight:448.58Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Formula:C30H52O4Purity:98.21% - 99.85%Color and Shape:SolidMolecular weight:476.73Ref: TM-TN2346
1mg37.00€5mg74.00€10mg111.00€25mg180.00€50mg269.00€100mg399.00€500mg905.00€1mL*10mM (DMSO)79.00€ADT-007
CAS:ADT-007 is a pan-RAS inhibitor with potent anticancer activity.Formula:C26H24FNO5Purity:97.75%Color and Shape:SoildMolecular weight:449.47Ref: TM-T85316
1mg49.00€5mg92.00€10mg131.00€25mg212.00€50mg373.00€100mg635.00€200mg1,035.00€1mL*10mM (DMSO)110.00€MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Formula:C26H26N4O2Purity:97.48%Color and Shape:SolidMolecular weight:426.51KRAS G12C inhibitor 61
CAS:KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, reflected in an IC50 value of 9 nM.Formula:C31H33ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:590.09Uplarafenib
CAS:Uplarafenib (B-Raf IN 10), a potent BRAF inhibitor (IC50: 50-100 nM), exhibits antitumor effects on solid cancers.Formula:C22H21F3N4O4SPurity:99.85%Color and Shape:SolidMolecular weight:494.49Ref: TM-T63333
1mg95.00€5mg202.00€10mg298.00€25mg630.00€50mg948.00€100mg1,644.00€500mg3,307.00€1mL*10mM (DMSO)224.00€AG126
CAS:AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). AG-126 weakly inhibits epidermal GFRK and platelet-derived GFRK.Formula:C10H5N3O3Purity:97.35%Color and Shape:SolidMolecular weight:215.16KRAS G12C inhibitor 19
CAS:KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in cellular assays, and the family inhibits tumor growth.Formula:C25H19ClF2N4O3SPurity:98.31%Color and Shape:SolidMolecular weight:528.96Talmapimod hydrochloride
CAS:Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective vs 20+ kinases.Formula:C27H31Cl2FN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46CC-90003
CAS:CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.Formula:C22H21F3N6O2Purity:99.42%Color and Shape:SolidMolecular weight:458.44Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Ref: TM-T1792
5mg35.00€10mg51.00€25mg80.00€50mg96.00€100mg144.00€200mg185.00€500mg309.00€1mL*10mM (DMSO)57.00€Exarafenib
CAS:Exarafenib (RAF/KIN_2787) is an oral pan-RAF inhibitor with antitumor properties, targeting MAPK signaling in cancer research.Formula:C26H34F3N5O3Purity:98.36% - 99.39%Color and Shape:SolidMolecular weight:521.58Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:100% - 99.85%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg43.00€2mg56.00€5mg88.00€10mg106.00€25mg213.00€50mg344.00€100mg550.00€1mL*10mM (DMSO)87.00€2-Aminooctadecane-1,3,4-Triol
CAS:2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.Formula:C18H39NO3Purity:≥98%Color and Shape:SolidMolecular weight:317.51(E/Z)-BIX02188
CAS:BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or ERK2.Formula:C25H24N4O2Purity:97.39% - 98.38%Color and Shape:SolidMolecular weight:412.48Ref: TM-T6324
1mg50.00€2mg66.00€5mg126.00€10mg229.00€25mg344.00€50mg517.00€100mg745.00€1mL*10mM (DMSO)143.00€
