MLK
MLKs are a group of kinases that can activate multiple MAPK pathways, including JNK and p38, by phosphorylating upstream MAP kinase kinases (MAP2Ks). MLKs are involved in cellular responses to stress, apoptosis, and neuroinflammation. Dysregulation of MLK activity is associated with neurodegenerative diseases and certain cancers. At CymitQuimica, we offer a range of high-quality MLK modulators to support your research in neurobiology, stress response, and signal transduction.
Products of "MLK"
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Found 9 products on this category.
GW806742X
CAS:GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.Formula:C25H22F3N7O4SPurity:98.30%Color and Shape:SolidMolecular weight:573.55IM-54
CAS:IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.Formula:C19H23N3O2Purity:99.05%Color and Shape:SolidMolecular weight:325.4LY-364947
CAS:LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Formula:C17H12N4Purity:99.41% - 99.96%Color and Shape:SolidMolecular weight:272.3Ref: TM-T2048
5mg65.00€10mg82.00€25mg143.00€50mg255.00€100mg374.00€200mg560.00€500mg877.00€1mL*10mM (DMSO)72.00€AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H31N7O2Purity:97.07%Color and Shape:SolidMolecular weight:485.58PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formula:C19H23N9O·HClPurity:97.11% - 99.93%Color and Shape:SolidMolecular weight:429.91Ref: TM-T2696
1mg60.00€2mg86.00€5mg127.00€10mg187.00€25mg326.00€50mg500.00€200mg948.00€1mL*10mM (DMSO)139.00€Necrosulfonamide
CAS:(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis.Formula:C18H15N5O6S2Purity:98.85% - 99.49%Color and Shape:SolidMolecular weight:461.47MLKL-IN-2
CAS:MLKL-IN-2 is an MLKL inhibitor with potential tumorigenic activity for the study of cellular necrosis-related diseases.Formula:C26H25N5OPurity:98.61%Color and Shape:SolidMolecular weight:423.51Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.23%Color and Shape:SolidMolecular weight:482(E/Z)-Necrosulfonamide
CAS:(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.Formula:C18H15N5O6S2Purity:97.62% - 98%Color and Shape:SolidMolecular weight:461.47
