p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Products of "p38 MAPK"
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SD-169
CAS:SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.Formula:C9H8N2OPurity:98.60%Color and Shape:SolidMolecular weight:160.17N-Feruloyloctopamine
CAS:N-Feruloyloctopamine is a natural product.Formula:C18H19NO5Purity:99.67%Color and Shape:SolidMolecular weight:329.35Ref: TM-TN1968
1mg89.00€5mg207.00€10mg304.00€25mg512.00€50mg740.00€100mg1,035.00€1mL*10mM (DMSO)172.00€Z16078526
CAS:Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.Formula:C18H17N3O4SPurity:98.93%Color and Shape:SolidMolecular weight:371.41Ro-3201195
CAS:Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.Formula:C19H18FN3O4Purity:100%Color and Shape:SolidMolecular weight:371.36PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purity:98.65%Color and Shape:SolidMolecular weight:360.34RWJ-67657
CAS:RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.Formula:C27H24FN3OPurity:99.66%Color and Shape:SolidMolecular weight:425.5Ref: TM-T16812
2mg47.00€5mg70.00€10mg96.00€25mg216.00€50mg349.00€100mg563.00€500mg1,188.00€1mL*10mM (DMSO)77.00€PLK1/p38γ-IN-1
CAS:PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellularFormula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purity:99.52%Color and Shape:SolidMolecular weight:405.41Ref: TM-T9697
1mg90.00€5mg215.00€10mg321.00€25mg582.00€50mg873.00€100mg1,216.00€1mL*10mM (DMSO)236.00€Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51SB-203580
CAS:Controlled ProductStability -200C Applications A pyridinyl imidazole which acts as a specific inhibitor of p38 MAP kinase. Does not inhibit the MAP kinase homologs JNK and p42 MAP kinase. References Kawasaki, H., et al.: J. Biol. Chem., 272, 18518 (1997), Ward, S.G., et al.: Biochem. Soc. Trans., 245, 304S (1997), Clerk, A., et al.: FEBS Lett., 426, 93 (1998),Formula:C21H16FN3OSColor and Shape:NeatMolecular weight:377.4310-Methoxy-canthin-6-one
CAS:10-Methoxy-canthin-6-one (Mtx-C) acts as a DNA damage inducer that embeds into DNA, promoting cell cycle arrest at the G2/M phase. This process triggers myeloid differentiation in acute myeloid leukemia cells (AML) and leukemia stem cells (LSC). Differentiation in AML and LSC cells is characterized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along with the activation of p38 MAPK. 10-Methoxy-canthin-6-one is utilized in the study of leukemia.Formula:C15H10N2O2Color and Shape:SolidMolecular weight:250.25Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:96.17% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64p38-α MAPK-IN-1
CAS:p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.Formula:C27H35N5O3Purity:99.52%Color and Shape:SolidMolecular weight:477.6Ref: TM-T12347
1mg88.00€5mg180.00€10mg281.00€25mg520.00€50mg777.00€100mg1,169.00€200mg1,568.00€1mL*10mM (DMSO)188.00€SB 203580 Hydrochloride
CAS:Controlled ProductFormula:C21H16FN3OS·HClColor and Shape:NeatMolecular weight:377.43 + 36.46AS-252424
CAS:Controlled ProductApplications AS-252424 is a novel, potent, and selective phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor. It is also an inhibitor of Casein kinase and PI3K p110α. References Pomel, V., et al.: J. Med. Chem., 49, 3857 (2006); Edling, C.E., et al.: Clin. Cancer Res., 16, 4928 (2010); Condliffe, A.M., et al.: Blood, 106, 1432 (2005)Formula:C14H8FNO4SColor and Shape:NeatMolecular weight:305.28LY 294002 Hydrochloride
CAS:Controlled ProductApplications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590). References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);Formula:C19H17NO3·(HCl)Color and Shape:NeatMolecular weight:343.8SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86Ref: TM-T7276
2mg38.00€5mg58.00€10mg90.00€25mg145.00€50mg226.00€100mg338.00€200mg472.00€1mL*10mM (DMSO)65.00€Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Formula:C20H15Cl3N2OSPurity:95.00%Color and Shape:SolidMolecular weight:437.77Ref: TM-T50005
5mg58.00€10mg82.00€25mg126.00€50mg182.00€100mg273.00€200mg409.00€1mL*10mM (DMSO)84.00€R1487
CAS:R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.Formula:C19H18F2N4O3Purity:99.77%Color and Shape:SolidMolecular weight:388.37AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; >> p38γ/δ; blocks LPS-induced TNFα, IC50: 3 nM.Formula:C29H29Cl2N5OPurity:98%Color and Shape:SolidMolecular weight:534.48SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Formula:C24H30O14Purity:100% - 99.57%Color and Shape:SolidMolecular weight:542.49Ref: TM-T4S2326
1mg96.00€5mg264.00€10mg415.00€25mg677.00€50mg935.00€100mg1,254.00€500mg2,527.00€1mL*10mM (DMSO)315.00€Licarin A
CAS:Licarin A is a natural anti-inflammatory lignan that inhibits PKCα/βII and p38 MAPK pathways, thereby decreasing TNF-α and prostaglandin D2 (PGD2)and COX-2.Formula:C20H22O4Purity:99.5%Color and Shape:SolidMolecular weight:326.39p38 MAP Kinase-IN-1
CAS:p38 MAP Kinase-IN-1 (Compound 4) is an inhibitor of p38, suitable for studies related to inflammation and autoimmune responses.Formula:C20H19FN6OColor and Shape:SolidMolecular weight:378.403BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Ref: TM-T6789
1mg87.00€2mg120.00€5mg210.00€10mg299.00€25mg502.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)210.00€VX 745
CAS:Controlled ProductApplications VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. VX 745 is a potential anti-inflammatory agents. Studies suggest that VX 745 may be useful in the treatment of Werner syndrome. References Haddad, J.J.: Curr. Opin. Invest. Drugs, 2, 1070 (2001); Duffy, J.P. et al.: ACS Med. Chem. Lett., 2, 758 (2011); Bagley, M.C. et al.: Pharmaceuticals, 3, 1842 (2010);Formula:C19H9Cl2F2N3OSColor and Shape:NeatMolecular weight:436.26Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formula:C31H33FN6O3Purity:98.41% - 99.66%Color and Shape:SolidMolecular weight:556.63Ref: TM-T6934
1mg47.00€5mg97.00€10mg139.00€25mg271.00€50mg435.00€100mg567.00€200mg810.00€1mL*10mM (DMSO)118.00€Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:100% - 98%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg52.00€2mg77.00€5mg115.00€10mg177.00€25mg378.00€50mg560.00€100mg800.00€1mL*10mM (DMSO)131.00€p38 Kinase inhibitor 4
CAS:Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 [1].Formula:C12H9Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:282.13Andrograpanin
CAS:Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.Formula:C20H30O3Purity:99.03%Color and Shape:SolidMolecular weight:318.45Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purity:≥95%Color and Shape:SolidMolecular weight:385.42SB 239063
CAS:SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4AKP-001
CAS:AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.Formula:C21H13ClF2N4O2Purity:99.50% - 99.92%Color and Shape:SolidMolecular weight:426.8Cristacarpin
CAS:Cristacarpin targets DNA repair-deficient yeast, induces ER stress and ROS, triggers senescence in pancreatic/breast cancer by halting G1 cell cycle.Formula:C21H22O5Purity:98%Color and Shape:SolidMolecular weight:354.402Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formula:C18H24OPurity:98.69% - 99.47%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purity:97.63% - 99.99%Color and Shape:SolidMolecular weight:406.38Ref: TM-T6927
1mg56.00€5mg119.00€10mg187.00€25mg378.00€50mg605.00€100mg852.00€500mg1,700.00€1mL*10mM (DMSO)131.00€AL 8697
CAS:AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formula:C21H21F3N4OPurity:98.96% - 99.26%Color and Shape:SolidMolecular weight:402.41Ref: TM-T10277
1mg70.00€5mg145.00€10mg207.00€25mg348.00€50mg495.00€100mg678.00€500mgTo inquire1mL*10mM (DMSO)169.00€CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39Ref: TM-T5393
1mg49.00€2mg65.00€5mg97.00€10mg160.00€25mg305.00€50mg472.00€100mg707.00€1mL*10mM (DMSO)106.00€SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formula:C19H20FN5OPurity:99.13% - 99.68%Color and Shape:SolidMolecular weight:353.39Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formula:C23H19F3N4O3Purity:97.53%Color and Shape:SolidMolecular weight:456.42Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurity:99.02% - ≥95%Color and Shape:SolidMolecular weight:436.26Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Ref: TM-T5S2283
1mg40.00€5mg85.00€10mg135.00€25mg216.00€50mg324.00€100mg472.00€500mg1,026.00€1mL*10mM (DMSO)88.00€MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Ref: TM-T5494
1mg39.00€5mg96.00€10mg153.00€25mg305.00€50mg454.00€100mg655.00€500mg1,406.00€1mL*10mM (DMSO)114.00€SJFα
CAS:SJFα (SJF alpha) degrades p38α and p38δ and can be used in cancer research.Formula:C59H67F2N7O11SPurity:95.25%Color and Shape:SolidMolecular weight:1120.27Dihydrocaffeic acid
CAS:Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.Formula:C9H10O4Purity:98.63%Color and Shape:SolidMolecular weight:182.17SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurity:97.79%Color and Shape:SolidMolecular weight:413.9Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFormula:C14H20N4OPurity:100% - 97.92%Color and Shape:SolidMolecular weight:260.33Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purity:100% - 99.76%Color and Shape:SolidMolecular weight:425.42Ref: TM-T6130
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg208.00€50mg313.00€100mg465.00€1mL*10mM (DMSO)87.00€LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formula:C25H25F3N4O4Purity:98.3% - 99.92%Color and Shape:SolidMolecular weight:502.49Ref: TM-T11898
1mg52.00€5mg122.00€10mg185.00€25mg363.00€50mg567.00€100mg690.00€200mg948.00€500mg1,444.00€1mL*10mM (DMSO)135.00€Lucidenic acid F
CAS:Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.Formula:C27H36O6Purity:98%Color and Shape:SolidMolecular weight:456.57Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purity:100% - 99%Color and Shape:SolidMolecular weight:404.32Emprumapimod
CAS:Emprumapimod, an oral p38α MAPK inhibitor, targets RPMI-8226 cells, curbs LPS-induced IL-6; IC50: 100 pM; for cardiomyopathy, acute pain.Formula:C24H29F2N5O3Purity:100% - 99.21%Color and Shape:SolidMolecular weight:473.52MAPK13-IN-1
CAS:MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formula:C20H23N5O2Purity:99.55%Color and Shape:SolidMolecular weight:365.43Ref: TM-T11943
1mg99.00€2mg144.00€5mg235.00€10mg354.00€25mg610.00€50mg885.00€100mg1,293.00€500mg2,585.00€1mL*10mM (DMSO)259.00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:100% - 98.11%Color and Shape:SolidMolecular weight:718.08Ref: TM-T1773
1g467.00€5mg40.00€10mg59.00€25mg87.00€50mg107.00€100mg140.00€200mg188.00€500mg313.00€1mL*10mM (DMSO)66.00€(S)-(-)-PH-797804
CAS:Controlled ProductFormula:C19H38N5O5Color and Shape:NeatMolecular weight:416.536Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formula:C24H25ClFN5O3Purity:97.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Ref: TM-T21312
5mg35.00€10mg51.00€25mg86.00€50mg115.00€100mg144.00€200mg177.00€500mg300.00€1mL*10mM (DMSO)52.00€Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82BI-3406
CAS:BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formula:C23H25F3N4O3Purity:99.20% - 99.66%Color and Shape:SolidMolecular weight:462.46Ref: TM-T12979
1mg73.00€5mg160.00€10mg250.00€25mg464.00€50mg663.00€100mg919.00€500mg1,833.00€1mL*10mM (DMSO)170.00€AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurity:98.35% - 98.9%Color and Shape:SolidMolecular weight:503.58Ref: TM-T6380
1mg52.00€5mg97.00€10mg166.00€25mg303.00€50mg467.00€100mg682.00€500mg1,415.00€1mL*10mM (DMSO)105.00€Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.Formula:C38H56N2O4Purity:98%Color and Shape:SolidMolecular weight:604.86SB 202190 hydrochloride
CAS:SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.Formula:C20H15ClFN3OPurity:99.99%Color and Shape:SolidMolecular weight:367.8Ref: TM-T35592
2mg49.00€5mg66.00€10mg90.00€25mg145.00€50mg207.00€100mg309.00€200mg459.00€1mL*10mM (DMSO)71.00€Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88Ref: TM-T10990
1mg58.00€5mg111.00€10mg160.00€25mg264.00€50mg396.00€100mg563.00€1mL*10mM (DMSO)124.00€PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.Formula:C22H18F2N4O3SColor and Shape:SolidMolecular weight:456.47Wortmannin
CAS:Controlled ProductApplications Wortmannin is a phosphatidylinositol 3 kinase (PI3K) inhibitor. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Liberman R., et. al.: J. Biol. Chem., 289, 1355 (2014)Formula:C23H24O8Color and Shape:White To Light YellowMolecular weight:428.43PS-166276
CAS:PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNFα assay.Formula:C20H30N8OColor and Shape:SolidMolecular weight:398.51p38α inhibitor 4
CAS:p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.Formula:C14H7F6N3OPurity:99.79%Color and Shape:SolidMolecular weight:347.215AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formula:C27H30FN5O3Purity:99.37%Color and Shape:SolidMolecular weight:491.56Ref: TM-T14381
1mg73.00€5mg160.00€10mg250.00€25mg507.00€50mg737.00€100mg1,026.00€1mL*10mM (DMSO)170.00€OVA-E1 peptide TFA
CAS:OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.Formula:C49H77F3N10O16Purity:98%Color and Shape:SolidMolecular weight:1119.19FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selectiveFormula:C29H28ClN5OPurity:98%Color and Shape:SolidMolecular weight:498.02M443
CAS:M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.Formula:C31H30F3N7O2Purity:98.95%Color and Shape:SolidMolecular weight:589.61SB220025
CAS:SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.Formula:C18H19FN6Purity:99.44%Color and Shape:SolidMolecular weight:338.38Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purity:98.56% - 99.05%Color and Shape:SolidMolecular weight:383.46Ref: TM-T2277
2mg35.00€5mg52.00€10mg78.00€25mg139.00€50mg225.00€100mg406.00€500mg920.00€1mL*10mM (DMSO)55.00€Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formula:C31H37N5O3Purity:97.73% - 98.80%Color and Shape:SolidMolecular weight:527.66Ref: TM-T6277
1g562.00€5mg37.00€10mg55.00€25mg79.00€50mg92.00€100mg127.00€200mg225.00€500mg379.00€1mL*10mM (DMSO)44.00€Hesperetin
CAS:Hesperetin belongs to the flavanone class of flavonoids.Formula:C16H14O6Purity:99.27%Color and Shape:SolidMolecular weight:302.28Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17Urolithin A
CAS:Applications Urolithin A is a major metabolite of ellagitannin and exhibits anti-inflammatory and antioxidant properties. References Ishimoto, H., et. al.: Bioorg. Med. Chem. Lett., 21, 5901 (2011);Formula:C13H8O4Color and Shape:NeatMolecular weight:228.20TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33Ref: TM-T4646
5mg39.00€10mg58.00€25mg104.00€50mg160.00€100mg244.00€500mgTo inquire1mL*10mM (DMSO)43.00€Adezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurity:99.42% - 99.87%Color and Shape:White SolidMolecular weight:377.43Talmapimod hydrochloride
CAS:Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective vs 20+ kinases.Formula:C27H31Cl2FN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46Rosin
CAS:Rosin is a natural product,may have therapeutic potential for the treatment of inflammationFormula:C15H20O6Purity:99.75% - 99.85%Color and Shape:SolidMolecular weight:296.32p38-α MAPK-IN-10
CAS:p38-α MAPK-IN-10 (Compound 6) is an inhibitor of p38α, with an IC50 value of 4 nM.Formula:C27H34Cl2N6Color and Shape:SolidMolecular weight:513.505Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purity:98.1% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09p38α inhibitor 3
CAS:p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation.Formula:C19H20FNOPurity:99.93%Color and Shape:SoildMolecular weight:297.37Aurantiamide
CAS:Aurantiamide inhibits cancer, inflammation, pain, and neuroinflammation by blocking autophagy and NF-κB, JNK, p38 pathways.Formula:C25H26N2O3Purity:98.88%Color and Shape:SolidMolecular weight:402.49Ref: TM-T5814
1mg137.00€5mg329.00€10mg490.00€25mg782.00€50mg1,035.00€100mg1,415.00€1mL*10mM (DMSO)469.00€AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79%Color and Shape:SolidMolecular weight:428.44
