Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC
- Adiponectin receptor
- ATPase
- Calcium Channel
- CFTR
- CGRP Receptor
- Chloride channel
- GABA Receptor
- Monoamine Transporter
- Monocarboxylate transporter
- Na-K-Cl cotransporter
- NKCC
- NPC1L1
- OAT
- OCT
- P-gp
- Potassium Channel
- Proton pump
- SGLT
- Sodium Channel
- TRP/TRPV Channel
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Products of "Membrane Transporter/Ion Channel"
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VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFormula:C20H22ClFN4O2SPurity:97.91%Color and Shape:SoildMolecular weight:436.93Diphyllin
CAS:Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.Formula:C21H16O7Purity:99.91% - 99.98%Color and Shape:SolidMolecular weight:380.35Ani9
CAS:Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.Formula:C17H17ClN2O3Purity:98.72%Color and Shape:SolidMolecular weight:332.78Ref: TM-T26630
1mg39.00€5mg84.00€10mg131.00€25mg269.00€50mg454.00€100mg655.00€500mg1,406.00€1mL*10mM (DMSO)92.00€Flindokalner
CAS:Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formula:C16H10ClF4NO2Purity:99.25%Color and Shape:SolidMolecular weight:359.7GFB-8438
CAS:GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).Formula:C16H14ClF3N4O2Purity:99.58%Color and Shape:SolidMolecular weight:386.76Ref: TM-T11394
2mg35.00€5mg52.00€10mg81.00€25mg117.00€50mg170.00€100mg250.00€200mg369.00€1mL*10mM (DMSO)58.00€PF 03716556
CAS:PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal refluxFormula:C22H26N4O3Purity:99.17% - 99.68%Color and Shape:SolidMolecular weight:394.47CFTR corrector 17
CAS:CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.Formula:C18H15FN2O2Color and Shape:SolidMolecular weight:310.32Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42β-Pompilidotoxin Acetate
β-Pompilidotoxin Acetate is a wasp venom peptide.Formula:C73H128N22O19Purity:98.64%Color and Shape:SolidMolecular weight:1617.93Ref: TM-T21769L
1mg46.00€2mg62.00€5mg94.00€10mg128.00€25mg212.00€50mg319.00€100mg447.00€200mg632.00€1mL*10mM (DMSO)187.00€Phenazopyridine hydrochloride
CAS:Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.Formula:C11H12ClN5Purity:99.27%Color and Shape:Brownish-Yellow Crystals Aqueous Solutions Are Yellow To Brick-Red And Slightly Acidic; They May Be Stabilized By The AdditionMolecular weight:249.7Fatostatin hydrobromide
CAS:Fatostatin hydrobromide (Fatostatin A HBr), an inhibitor of sterol regulatory element binding protein (SREBP), impairs the activation of SREBP-1 and SREBP-2.Formula:C18H18N2S·HBrPurity:98.62% - 99.91%Color and Shape:SolidMolecular weight:375.33AMG-0347
CAS:AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.Formula:C24H26F3N3O2Purity:99.7%Color and Shape:SolidMolecular weight:445.48Ref: TM-T29968
1mg226.00€5mg552.00€10mg735.00€25mg1,111.00€50mg1,491.00€100mg2,005.00€200mg2,707.00€1mL*10mM (DMSO)567.00€Songorine
CAS:Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.Formula:C22H31NO3Purity:98% - 99.92%Color and Shape:SolidMolecular weight:357.49Silperisone HCl
CAS:Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.Formula:C15H25ClFNSiPurity:100%Color and Shape:SolidMolecular weight:301.93,4-Dihydroxypyrovalerone HCl
CAS:3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).Formula:C15H22ClNO3Color and Shape:SolidMolecular weight:299.79Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Formula:C22H31NO3Purity:100% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49Talatisamine
CAS:Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formula:C24H39NO5Purity:98.62% - 99.44%Color and Shape:SolidMolecular weight:421.57XE 991 dihydrochloride
CAS:XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Ref: TM-T16347
2mg34.00€5mg52.00€10mg85.00€25mg156.00€50mg245.00€100mg364.00€200mg517.00€1mL*10mM (DMSO)58.00€Pikamilone
CAS:Pikamilone (Picamilon) is an intelligent medicine.Formula:C10H12N2O3Purity:99.38%Color and Shape:White Crystalline PowderMolecular weight:208.21Quinine
CAS:Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42Strophanthidin
CAS:Strophanthidin (Strophanthidine) can induce calcium overload in vivo.Formula:C23H32O6Purity:93%Color and Shape:SolidMolecular weight:404.5δ-Theraphotoxin-Hm1a toxin
δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [Formula:C170H240N48O53S6Purity:98%Color and Shape:SolidMolecular weight:3996.4ICA-121431
CAS:ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.Formula:C23H19N3O3S2Purity:98%Color and Shape:SolidMolecular weight:449.55JT010
CAS:JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).Formula:C16H19ClN2O3SPurity:98.5%Color and Shape:SolidMolecular weight:354.85Soraprazan
CAS:BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.Formula:C21H25N3O3Purity:97.69% - 99.84%Color and Shape:SolidMolecular weight:367.44Bufalin
CAS:Bufalin: a cardiotonic, antineoplastic glycoside in ChanSu; from toad venom; inhibits Na+/K+-ATPase, triggers apoptosis via MAPK pathway.Formula:C24H34O4Purity:98% - 99.8%Color and Shape:White SolidMolecular weight:386.52Picrotin
CAS:Picrotin is an inhibitor of glycine receptors. Picrotin blocks α2 GlyR, α1 GlyR, and α3 GlyR and can be used in studies about neurotransmission.Formula:C15H18O7Purity:97.11%Color and Shape:SolidMolecular weight:310.3ZTZ240
CAS:ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.Formula:C12H8ClFN2OPurity:99.93%Color and Shape:SolidMolecular weight:250.66M8-B Hydrochloride
CAS:M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.Formula:C22H25ClN2O3SPurity:99.33%Color and Shape:SolidMolecular weight:432.96Ref: TM-T8442
2mg35.00€5mg52.00€10mg74.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)64.00€Liriodendrin
CAS:Liriodendrin controls lung inflammation, NF-kB activity, VEGF levels, and has anti-inflammatory, pain-relieving, and blood sugar-reducing effects.Formula:C34H46O18Purity:98%Color and Shape:SolidMolecular weight:742.72VU591
CAS:1222810-74-3Formula:C16H12N6O5Purity:99.29% - 99.53%Color and Shape:SolidMolecular weight:368.3ML329
CAS:ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.Formula:C16H12N2O4SPurity:98.96%Color and Shape:SolidMolecular weight:328.34Ref: TM-T4028
1mg52.00€2mg73.00€5mg115.00€10mg187.00€25mg424.00€50mg627.00€100mg893.00€1mL*10mM (DMSO)118.00€Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formula:C106H175N37O25S4Purity:98%Color and Shape:SolidMolecular weight:2496.02CFTR corrector 9
CAS:CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.Formula:C16H14N2O4Purity:98.24%Color and Shape:SolidMolecular weight:298.29Ref: TM-T60653
2mg42.00€5mg64.00€10mg92.00€25mg178.00€50mg266.00€100mg383.00€200mg537.00€1mL*10mM (DMSO)62.00€Astemizole
CAS:Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Formula:C28H31FN4OPurity:98.24% - 99.67%Color and Shape:White Crystals SolidMolecular weight:458.57Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purity:98%Color and Shape:SolidMolecular weight:208.05Clopamide
CAS:Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.Formula:C14H20ClN3O3SPurity:99.21%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:345.84NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formula:C23H30FNO4SPurity:99.89%Color and Shape:SolidMolecular weight:435.55Ref: TM-T12181
1mg104.00€5mg255.00€10mg406.00€25mg700.00€50mg938.00€100mg1,378.00€1mL*10mM (DMSO)280.00€Rufinamide
CAS:Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders.Formula:C10H8F2N4OPurity:99.77% - 99.89%Color and Shape:White PowderMolecular weight:238.19L-Palmitoylcarnitine
CAS:L-Palmitoylcarnitine (L-PC) inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.Formula:C23H45NO4Purity:97% - 99.81%Color and Shape:SolidMolecular weight:399.61NS6180
CAS:NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Ref: TM-T1752
1mg35.00€2mg49.00€5mg70.00€10mg106.00€25mg225.00€50mg365.00€100mg545.00€1mL*10mM (DMSO)70.00€Antidepressant agent 9
CAS:Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.Formula:C17H24N2Color and Shape:SolidMolecular weight:256.386Divaplon
CAS:Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.Formula:C17H17N3O2Purity:96.90% - 97.49%Color and Shape:SolidMolecular weight:295.34Transcainide
CAS:Transcainide (R 54718), an oral lidocaine-like antiarrhythmic, blocks BTX-activated Na+ channels in heart/muscle.Formula:C22H35N3O2Purity:100%Color and Shape:SolidMolecular weight:373.53NCS-382 sodium
CAS:NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFormula:C13H13NaO3Purity:98%Color and Shape:SolidMolecular weight:240.23Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Formula:C13H21ClN2O3SPurity:99.76%Color and Shape:White Crystalline PowderMolecular weight:320.84ML133 hydrochloride
CAS:ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82Ref: TM-T6592
5mg50.00€10mg66.00€25mg106.00€50mg170.00€100mg274.00€200mg354.00€500mg597.00€1mL*10mM (DMSO)52.00€Neosolaniol
CAS:Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.Formula:C19H26O8Purity:98%Color and Shape:SolidMolecular weight:382.4
