Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC
- Adiponectin receptor
- ATPase
- Calcium Channel
- CFTR
- CGRP Receptor
- Chloride channel
- GABA Receptor
- Monoamine Transporter
- Monocarboxylate transporter
- Na-K-Cl cotransporter
- NKCC
- NPC1L1
- OAT
- OCT
- P-gp
- Potassium Channel
- Proton pump
- SGLT
- Sodium Channel
- TRP/TRPV Channel
Show 13 more subcategories
Products of "Membrane Transporter/Ion Channel"
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L-DABA
CAS:L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).Formula:C4H10N2O2Purity:99.32%Color and Shape:SolidMolecular weight:118.13Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.63%Color and Shape:SolidMolecular weight:366.46Dendrotoxin K TFA
Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].Formula:C294H462N84O75S6·XC2HF3OC2Purity:98%Color and Shape:SolidMolecular weight:6559.66 (free base)VB124
CAS:VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate importand expor in MDA-MB-231 cells.Cost-effective and quality-assured.Formula:C23H23ClN2O4Purity:99.21% - 99.57%Color and Shape:SoildMolecular weight:426.89Ref: TM-T60165
1mg119.00€5mg283.00€10mg472.00€25mg948.00€50mg1,510.00€100mg2,023.00€1mL*10mM (DMSO)319.00€(+)-Bicuculline methiodide
CAS:(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Formula:C21H20INO6Purity:99.24%Color and Shape:SolidMolecular weight:509.29Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Color and Shape:Odour SolidIlaprazole sodium
CAS:Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.Formula:C19H17N4NaO2SPurity:99.06%Color and Shape:SolidMolecular weight:388.42Ref: TM-T1756
1mg37.00€2mg52.00€5mg77.00€10mg92.00€25mg188.00€50mg305.00€100mg487.00€1mL*10mM (DMSO)79.00€Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Ref: TM-T1073
5mg38.00€10mg52.00€25mg87.00€50mg117.00€100mg170.00€200mg250.00€500mg424.00€1mL*10mM (DMSO)55.00€PF-04856264
CAS:PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.Formula:C20H15N5O3S2Color and Shape:SolidMolecular weight:437.5Isopulegol
CAS:Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possiblyFormula:C10H18OPurity:98%Color and Shape:Colorless Liquid LimpidMolecular weight:154.25Crotamine
Crotamine, a 42 amino acid toxin featuring three disulfide bridges, functions as a Na+ channel modulator with analgesic properties.Formula:C214H326N64O54S7Purity:98%Color and Shape:SolidMolecular weight:4883.73Levolansoprazole
CAS:Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM).Formula:C16H14F3N3O2SPurity:98.62%Color and Shape:SolidMolecular weight:369.36Ref: TM-T20714
1mg135.00€2mg188.00€5mg329.00€10mg467.00€25mg677.00€50mg929.00€100mg1,244.00€200mg1,681.00€1mL*10mM (DMSO)331.00€KPT185
CAS:KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.Formula:C16H16F3N3O3Purity:98%Color and Shape:SolidMolecular weight:355.31Pyrimidinone 8
CAS:Pyrimidinone 8 is a reversible, linear non-competitive inhibitor of divalent metal transporter 1 (DMT1) with a Ki of 20 μM (hDMT1). It does not affect the surface expression of hDMT1 and is not influenced by extracellular pH. Pyrimidinone 8 inhibits hDMT1-mediated iron uptake, with an IC50 of 13.8 μM.Formula:C10H12N4OColor and Shape:SolidMolecular weight:204.229Ralfinamide mesylate
CAS:Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.Formula:C18H23FN2O5SPurity:99.83%Color and Shape:SolidMolecular weight:398.45Ref: TM-T7547
1mg78.00€5mg170.00€10mg256.00€25mg423.00€50mg562.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)259.00€ANO1-IN-1
CAS:ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.Formula:C18H28N2O2SPurity:99.66%Color and Shape:SolidMolecular weight:336.49Esomeprazole Magnesium trihydrate
CAS:Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophagealFormula:C34H42MgN6O9S2Purity:98.52%Color and Shape:Off-White PowderMolecular weight:767.17Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormula:C270H413N69O79S4Purity:98%Color and Shape:SolidMolecular weight:6017.84Ancistrotecine B
Ancistrotecine B (Compound 2), a Nav1.7 channel inhibitor (IC50: 0.73 μM), has been shown to alleviate inflammatory pain in mice [1].Formula:C26H31NO4Purity:98%Color and Shape:SolidMolecular weight:421.53TRPM8 antagonist 3
CAS:TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).Formula:C13H12N2O4SPurity:99.25%Color and Shape:SolidMolecular weight:292.31Ref: TM-T9709
1mg62.00€5mg135.00€10mg202.00€25mg335.00€50mg490.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)149.00€Quinidine hydrochloride monohydrate
CAS:Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.Formula:C20H27ClN2O3Purity:94.4% - 94.72%Color and Shape:SolidMolecular weight:378.89Emamectin Benzoate
CAS:Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropodsFormula:C56H81NO15Purity:98.68%Color and Shape:SolidMolecular weight:1008.256Bamaquimast
CAS:Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.Formula:C16H21N3O3Purity:98.40%Color and Shape:SolidMolecular weight:303.365-Tridecanol
CAS:5-Tridecanol blocks ion flux in sodium channels.Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.36µ-Conotoxin BuIIIC
CAS:μ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) effectively inhibits the NaV1.4 sodium channel [1].Formula:C116H189N49O34S6Purity:98%Color and Shape:SolidMolecular weight:3006.44A-1165442
CAS:A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.Formula:C22H20ClF2N3O2Color and Shape:SolidMolecular weight:431.86CP-409092
CAS:CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.Formula:C17H19N3O2Purity:98%Color and Shape:SolidMolecular weight:297.35NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Formula:C16H16N2O4Purity:99.95%Color and Shape:Light Yellow To Yellow SolidMolecular weight:300.31Ampullosporin A
CAS:Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.Formula:C77H127N19O19Color and Shape:SolidMolecular weight:1622.95Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.50% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Tamapin TFA
Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated KFormula:C146H238N44O41S6·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3458.11 (free base)(-)-Blebbistatin
CAS:(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.Formula:C18H16N2O2Purity:99.38% - 99.61%Color and Shape:SolidMolecular weight:292.33α-Thujone
CAS:α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formula:C10H16OPurity:98.16% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23Reserpine hydrochloride
CAS:Reserpine hydrochloride inhibits the uptake of norepinephrine, depletion of catecholamines and serotonin in axon terminals, antihypertensive and antipsychotic.Formula:C33H41ClN2O9Purity:99.96%Color and Shape:SolidMolecular weight:645.14KS176
CAS:KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.Formula:C22H19N3O5Purity:99.55% - 99.78%Color and Shape:SolidMolecular weight:405.4Ref: TM-T3581
2mg34.00€5mg51.00€10mg86.00€25mg167.00€50mg305.00€100mg439.00€200mg615.00€1mL*10mM (DMSO)51.00€Sodium ionophore III
CAS:Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.Formula:C34H52N2O4Purity:98.2% - 98.54%Color and Shape:SolidMolecular weight:552.79ABCG2-IN-2
CAS:ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrugFormula:C25H34N4O4Purity:98%Color and Shape:SolidMolecular weight:454.56VRT-532
CAS:VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.Formula:C16H14N2OPurity:100% - 99.89%Color and Shape:SolidMolecular weight:250.3ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Formula:C17H23NOPurity:99.74%Color and Shape:SolidMolecular weight:257.37Rabeprazole Sulfide
CAS:Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.Formula:C18H21N3O2SPurity:99.34% - 99.80%Color and Shape:Off-White Crystalline PowderMolecular weight:343.44HC-030031
CAS:HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.Formula:C18H21N5O3Purity:99.69% - ≥95%Color and Shape:SolidMolecular weight:355.39Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Formula:C10H8N2O2S2ZnPurity:99.47% - 99.64%Color and Shape:Off-White To Tan PowderMolecular weight:317.71Encecalin
CAS:Encecalin and demethylencecalin from H. quinquenervis inhibit photosystem II, and hinder weed/crop seed germination and growth.Formula:C14H16O3Purity:98%Color and Shape:SolidMolecular weight:232.28Doxapram
CAS:Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.Formula:C24H30N2O2Purity:99.42%Color and Shape:SolidMolecular weight:378.51Phenibut
CAS:Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).Formula:C10H13NO2Purity:99.55%Color and Shape:SolidMolecular weight:179.22Tetrabenazine Racemate
CAS:Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).Formula:C19H27NO3Purity:98.86%Color and Shape:SolidMolecular weight:317.42Nicainoprol
CAS:Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.Formula:C21H27N3O3Purity:99.54%Color and Shape:SolidMolecular weight:369.46Ref: TM-T4539
1mg140.00€5mg344.00€10mg512.00€25mg812.00€50mg1,093.00€100mg1,473.00€1mL*10mM (DMSO)350.00€Oxybuprocaine hydrochloride
CAS:Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.Formula:C17H29ClN2O3Purity:99.87%Color and Shape:White Crystalline PowderMolecular weight:344.88Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Formula:C21H24O10Purity:99.58% - 99.76%Color and Shape:Solid CrystallineMolecular weight:436.41CRM1-IN-2
CRM1-IN-2 (Compound KL2) is a noncovalent inhibitor that targets CRM1, localizing it to the nuclear periphery, depleting its nuclear presence, and inhibitingFormula:C29H48N2O5Purity:98%Color and Shape:SolidMolecular weight:504.7
