Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Products of "Potassium Channel"
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Miconazole
CAS:Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.Formula:C18H14Cl4N2OPurity:100% - 99.78%Color and Shape:SolidMolecular weight:416.13Prazosin hydrochloride
CAS:Prazosin HCl, a synthetic antiadrenergic, treats hypertension, heart failure, and more by relaxing blood vessels with an unclear mechanism.Formula:C19H22ClN5O4Purity:99.87% - 99.89%Color and Shape:White To Tan Powder Off-White To Yellow PowderMolecular weight:419.86Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.Formula:C14H12N6OPurity:99.32% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81ICA 110381
CAS:ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Aprikalim
CAS:Aprikalim opens KATP channels, protects the heart, and at high doses, dilates blood vessels.Formula:C12H16N2OS2Purity:99.28% - 99.38%Color and Shape:SolidMolecular weight:268.4Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:Crystal PowderMolecular weight:435.31Pinacidil monohydrate
CAS:Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Formula:C13H21N5OPurity:99.94% - 99.96%Color and Shape:PowderMolecular weight:263.34Cromakalim
CAS:Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33KV1.3-IN-2
CAS:KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818Guanfu base A
CAS:Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.Formula:C24H31NO6Purity:99.71% - 99.85%Color and Shape:SolidMolecular weight:429.5ZM 226600
CAS:ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.Formula:C16H14F3NO4SPurity:100%Color and Shape:SolidMolecular weight:373.35Ref: TM-T23563
2mg35.00€5mg50.00€10mg80.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)55.00€P-1075
CAS:P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.Formula:C12H17N5Purity:99.35%Color and Shape:SolidMolecular weight:231.3Ref: TM-T16420
1mg60.00€2mg88.00€5mg126.00€10mg202.00€25mg374.00€50mg560.00€100mg800.00€500mg1,644.00€1mL*10mM (DMSO)96.00€Rosuvastatin calcium
CAS:Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormula:(C22H27FN3O6S)CaPurity:98.85% - 99.68%Color and Shape:White To Off-White Crystalline SolidMolecular weight:1001.14Oxybutynin chloride
CAS:Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.Formula:C22H32ClNO3Purity:98.71% - 99.17%Color and Shape:White PowderMolecular weight:393.96Diazoxide
CAS:Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formula:C8H7ClN2O2SPurity:99% - 99.83%Color and Shape:SolidMolecular weight:230.67Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purity:97.11% - 99.23%Color and Shape:Lactic AcidosisMolecular weight:241.72Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purity:98.25% - 99.95%Color and Shape:Colorless Crystals From Ethanol + Ether White Crystalline PowderMolecular weight:512.33Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Tipepidine hydrochloride
CAS:Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Formula:C15H18ClNS2Purity:99.97%Color and Shape:SolidMolecular weight:311.89(±)-Naringenin
CAS:(±)-Naringenin (Naringenine) is a natural product.Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25ML277
CAS:ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59Rimtuzalcap
CAS:Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formula:C18H24F2N6OPurity:99.54%Color and Shape:SolidMolecular weight:378.42Ref: TM-T9522
1mg35.00€5mg78.00€10mg111.00€25mg215.00€50mg320.00€100mg452.00€200mg632.00€1mL*10mM (DMSO)34.00€BSH-IN-1
CAS:BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B.Formula:C25H41FO3Purity:98%Color and Shape:SolidMolecular weight:408.59Ref: TM-T10623
1mg116.00€5mg283.00€10mg445.00€25mg738.00€50mg1,017.00€100mg1,415.00€1mL*10mM (DMSO)310.00€Budiodarone tartrate
CAS:Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.Formula:C31H37I2NO11Purity:97.44%Color and Shape:SolidMolecular weight:853.44Gliclazide
CAS:Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of theFormula:C15H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:323.41LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82E-4031
CAS:E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44KCNQ1 activator-1
CAS:N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57H3B-120
CAS:H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.Formula:C19H24N4O2SPurity:99.03% - 99.2%Color and Shape:SolidMolecular weight:372.48Ref: TM-T11529
1mg113.00€5mg235.00€10mg393.00€25mg657.00€50mg935.00€100mg1,264.00€500mg2,527.00€1mL*10mM (DMSO)259.00€(+)-KCC2 blocker 1
CAS:(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).Formula:C22H25NO5SPurity:98.12%Color and Shape:SolidMolecular weight:415.5Ref: TM-T12504
1mg115.00€2mg172.00€5mg255.00€10mg374.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,147.00€1mL*10mM (DMSO)284.00€5-Hydroxydecanoate sodium
CAS:5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.Formula:C10H19NaO3Purity:≥98%Color and Shape:SolidMolecular weight:210.25HUP30
CAS:HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.Formula:C14H15N3O3SPurity:99.8%Color and Shape:SolidMolecular weight:305.35Ref: TM-TNU0864
2mg35.00€5mg50.00€10mg80.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)55.00€Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:SolidMolecular weight:353.81JNJ-26489112
CAS:JNJ-26489112 is a CNS-active agent and an inhibitor of voltage-gated Na+ channels and N-type Ca2+ channels.Formula:C9H11ClN2O4SPurity:99.31%Color and Shape:SolidMolecular weight:278.71Ifenprodil Tartrate
CAS:Ifenprodil is a selective NMDA receptor (glutamate) antagonist.Formula:C21H27NO2C4H6O6Purity:99.02% - 99.55%Color and Shape:SolidMolecular weight:400.49Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormula:C31H32N4O2Purity:98.90%Color and Shape:SolidMolecular weight:492.61Kv7.2/Kv7.3 agonist 1
CAS:Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.Formula:C14H14FN3O2Color and Shape:SolidMolecular weight:275.28MK-0448
CAS:MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.Formula:C24H21FN4O2SPurity:99.25% - 99.79%Color and Shape:SolidMolecular weight:448.51Vernakalant Hydrochloride
CAS:Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.Formula:C20H32ClNO4Purity:99.04%Color and Shape:SolidMolecular weight:385.93Ref: TM-T17227
1mg74.00€2mg97.00€5mg170.00€10mg274.00€25mg523.00€50mg753.00€100mg1,035.00€1mL*10mM (DMSO)187.00€Tannic acid
CAS:Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Formula:C76H52O46Purity:AR - ARColor and Shape:Light Yellow To Light Brown Solid Solid Particulate/PowderMolecular weight:1701.2Doxapram hydrochloride hydrate
CAS:Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.Formula:C24H33ClN2O3C24H30N2O2·ClH·H2OPurity:100% - 99.64%Color and Shape:SolidMolecular weight:432.99Acetohexamide
CAS:Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity.Formula:C15H20N2O4SPurity:99.19% - 99.85%Color and Shape:Crystals From 90% Aq EthanolMolecular weight:324.4NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99%Color and Shape:SolidMolecular weight:380.24Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formula:C33H40N2O9Purity:98.85% - 99.81%Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Molecular weight:608.68GAL-021
CAS:GAL-021 an intravenous BKCa-channel blocker.Formula:C11H22N6OPurity:97.71% - 99.73%Color and Shape:SolidMolecular weight:254.33Ref: TM-T3557
1mg37.00€5mg74.00€10mg103.00€25mg187.00€50mg283.00€100mg437.00€500mg938.00€1mL*10mM (DMSO)85.00€Proflavine Hemisulfate
CAS:Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formula:C13H12N3O2S0Purity:99.55%Color and Shape:Orange To Red PowderMolecular weight:258.29KNa1.1-IN-2
CAS:KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48DCEBIO
CAS:DCEBIO, a 1-EBIO derivative, enhances Cl- secretion via hIK1 K+ channel and apical conductance in T84 cells.Formula:C9H8Cl2N2OPurity:99.89%Color and Shape:SolidMolecular weight:231.08Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83Ref: TM-T15207
1mg62.00€5mg116.00€10mg170.00€25mg283.00€50mg424.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)128.00€Ropivacaine hydrochloride
CAS:Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFormula:C17H26N2O·HClPurity:99.85%Color and Shape:SolidMolecular weight:310.86VU0810464
CAS:VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.Formula:C18H21ClFN3OPurity:99.62%Color and Shape:SolidMolecular weight:349.83Ref: TM-T7899
1mg62.00€5mg135.00€10mg207.00€25mg349.00€50mg467.00€100mg620.00€200mg843.00€1mL*10mM (DMSO)149.00€Potassium Channel Activator 1
CAS:Potassium Channel Activator 1 aids treatment of ADHD, schizophrenia, and mood disorders by targeting the dopaminergic system.Formula:C19H23N3O3Purity:99.60%Color and Shape:SolidMolecular weight:341.4Minoxidil sulfate
CAS:Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33Ref: TM-TQ0150
1mg52.00€2mg78.00€5mg99.00€10mg150.00€25mg335.00€50mg499.00€100mg722.00€1mL*10mM (DMSO)110.00€Aekatperone
Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).Formula:C20H25N5O2SColor and Shape:SolidMolecular weight:399.51Kv3 modulator 1
CAS:Kv3 modulator 1 is a voltage-gated potassium channel Kv3 modulator that can be used to study neurologic-level diseases.Formula:C20H20N4O4Purity:99.10%Color and Shape:SolidMolecular weight:380.4Almitrine mesylate
CAS:Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.Formula:C28H37F2N7O6S2Purity:99.96%Color and Shape:CoaMolecular weight:669.76BKCa activator-1
BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purity:99.48% - 99.85%Color and Shape:SolidMolecular weight:402.91Ref: TM-T2170
5mg57.00€10mg86.00€25mg138.00€50mg243.00€100mg470.00€200mg717.00€500mg1,111.00€1mL*10mM (DMSO)63.00€ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.30%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg39.00€5mg84.00€10mg117.00€25mg188.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)93.00€Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formula:C18H28N2O·HClPurity:100% - 100%Color and Shape:SolidMolecular weight:324.89NS5806
CAS:NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).Formula:C16H8Br2F6N6OPurity:97.95%Color and Shape:SolidMolecular weight:574.07Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purity:98% - 99.94%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.41Sigma-1 receptor antagonist 3
CAS:Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).Formula:C19H23ClFN3OPurity:100%Color and Shape:SolidMolecular weight:363.864-Hydroxytolbutamide
CAS:4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35VU591 hydrochloride
CAS:VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.Formula:C16H13ClN6O5Purity:98.93% - 99.22%Color and Shape:SolidMolecular weight:404.76Ref: TM-T13320
1mg35.00€5mg74.00€10mg111.00€25mg226.00€50mg386.00€100mg540.00€200mg735.00€1mL*10mM (DMSO)84.00€ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Ref: TM-T9009
1mg43.00€5mg92.00€10mg144.00€25mg298.00€50mg469.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€VU0463271
CAS:VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.Formula:C19H18N4OS2Purity:99.75%Color and Shape:SolidMolecular weight:382.5CLP290
CAS:CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatricFormula:C19H21FN4O3SPurity:100% - 100%Color and Shape:SolidMolecular weight:404.46Bupivacaine hydrochloride monohydrate
CAS:Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.Formula:C18H31ClN2O2Purity:99.91%Color and Shape:SolidMolecular weight:342.9Paxilline
CAS:Paxilline, an indole alkaloid mycotoxin from Penicillium paxilli, is a specific inhibitor of BK-type K(+) channels with anticonvulsant activity.Formula:C27H33NO4Purity:98%Color and Shape:White PowderMolecular weight:435.56BAPTA-AM
CAS:BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formula:C34H40N2O18Purity:98% - 99.47%Color and Shape:White Powder Or Crystalline PowderMolecular weight:764.68GW 542573X
CAS:GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curveFormula:C19H28N2O5Purity:99.91%Color and Shape:SolidMolecular weight:364.44ICA
CAS:ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).Formula:C13H10N4SPurity:99.66%Color and Shape:SolidMolecular weight:254.31Ref: TM-T15546
1mg96.00€5mg170.00€10mg255.00€25mg409.00€50mg567.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)238.00€Mitiglinide calcium hydrate
CAS:Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.Formula:C38H52CaN2O8Purity:100% - 99.73%Color and Shape:White SolidMolecular weight:704.91Ursodeoxycholic acid
CAS:Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.Formula:C24H40O4Purity:99.74% - ≥95%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Vesnarinone HCl
Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.Formula:C22H26ClN3O4Purity:99.17%Color and Shape:SoildMolecular weight:431.91Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formula:C24H21Cl2FN4OPurity:98.25% - 98.67%Color and Shape:SolidMolecular weight:471.35Clamikalant sodium
CAS:Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Ref: TM-T63330
1mg52.00€5mg100.00€10mg191.00€25mg384.00€50mg595.00€100mg969.00€200mg1,296.00€1mL*10mM (DMSO)105.00€AVE-0118
CAS:AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.Formula:C30H29N3O3Purity:98.89% - 99.52%Color and Shape:SolidMolecular weight:479.57Ref: TM-T26689
1mg73.00€5mg139.00€10mg183.00€25mg320.00€50mg474.00€100mg688.00€500mg1,444.00€1mL*10mM (DMSO)168.00€Endoxifen (Z-isomer)
CAS:Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Formula:C25H27NO2Purity:99.81%Color and Shape:SolidMolecular weight:373.49Linoleoyl glycine
CAS:Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.Formula:C20H35NO3Purity:98.96%Color and Shape:SolidMolecular weight:337.5RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurity:98.04%Color and Shape:SolidMolecular weight:392.47Ref: TM-T12786
1mg51.00€5mg144.00€10mg235.00€25mg399.00€50mg560.00€100mg787.00€200mg1,093.00€1mL*10mM (DMSO)131.00€VU590
CAS:VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.Formula:C24H32N4O7Purity:98.06%Color and Shape:SolidMolecular weight:488.53ML402
CAS:ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.Formula:C14H14ClNO2SPurity:98.93%Color and Shape:SolidMolecular weight:295.78Ref: TM-T16109
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg235.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)87.00€Ersentilide
CAS:Ersentilide, a benzamide derivative, functions as both a β1-adrenergic receptor antagonist and an Ikr blocker. It has demonstrated efficacy in animal models of cardiac arrhythmias.Formula:C21H26N4O5SColor and Shape:SolidMolecular weight:446.52GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formula:C20H24Cl3N3OPurity:100%Color and Shape:SolidMolecular weight:428.78Ref: TM-T7195
1mg79.00€2mg101.00€5mg149.00€10mg195.00€25mg373.00€50mg562.00€100mg802.00€1mL*10mM (DMSO)145.00€VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Formula:C20H32BrClN2O2Purity:100%Color and Shape:SolidMolecular weight:447.84Ref: TM-T13316
5mg39.00€10mg65.00€25mg108.00€50mg177.00€100mg304.00€200mg437.00€1mL*10mM (DMSO)44.00€SKA-111
CAS:SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.Formula:C12H10N2SPurity:99.79%Color and Shape:SolidMolecular weight:214.29Ref: TM-T24799
1mg70.00€5mg153.00€10mg250.00€25mg504.00€50mg727.00€100mg1,017.00€500mg2,043.00€1mL*10mM (DMSO)167.00€Hypophyllanthin
CAS:Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.Formula:C24H30O7Purity:98.39%Color and Shape:SolidMolecular weight:430.49Pinacidil
CAS:Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure andFormula:C13H19N5Purity:99.92%Color and Shape:SolidMolecular weight:245.32TRAM 39
CAS:TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.Formula:C20H14ClNPurity:99.51%Color and Shape:SolidMolecular weight:303.78Ref: TM-T23471
1mg35.00€2mg49.00€5mg74.00€10mg107.00€25mg210.00€50mg335.00€100mg530.00€500mg1,121.00€NS8593 hydrochloride
CAS:NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .Formula:C17H18ClN3Purity:99.77%Color and Shape:SolidMolecular weight:299.8Ref: TM-T12256
1mg46.00€2mg59.00€5mg93.00€10mg159.00€25mg350.00€50mg525.00€100mg757.00€1mL*10mM (DMSO)96.00€ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurity:99.28% - 99.82%Color and Shape:SoildMolecular weight:306.33Ref: TM-T67917
2mg46.00€5mg70.00€10mg101.00€25mg167.00€50mg226.00€100mg331.00€200mg449.00€1mL*10mM (DMSO)74.00€CHET3
CAS:CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.Formula:C21H21N5O3SPurity:100% - 99.91%Color and Shape:SoildMolecular weight:423.49Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Formula:C21H27NO3Purity:99.02%Color and Shape:SolidMolecular weight:341.44NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23Ref: TM-T3102
1mg37.00€2mg52.00€5mg79.00€10mg97.00€25mg170.00€50mg253.00€100mg376.00€1mL*10mM (DMSO)87.00€Guanosine 5'-diphosphate
CAS:Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.Formula:C10H15N5O11P2Purity:100% - 98.46%Color and Shape:SolidMolecular weight:443.2ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purity:97.29%Color and Shape:SolidMolecular weight:388.4Ref: TM-T9070
1mg35.00€2mg48.00€5mg70.00€10mg96.00€25mg188.00€50mg311.00€100mg512.00€1mL*10mM (DMSO)77.00€Branaplam
CAS:Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.Formula:C22H27N5O2Purity:97.81% - 99.73%Color and Shape:SolidMolecular weight:393.48Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:98.45% - 99.51%Color and Shape:SoildMolecular weight:532.5239-Hydroxycanthin-6-one
CAS:9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E.Formula:C14H8N2O2Purity:98%Color and Shape:SolidMolecular weight:236.23Endoxifen Z-isomer hydrochloride
CAS:Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.Formula:C25H28ClNO2Color and Shape:SolidMolecular weight:409.95Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formula:(C20H36N2O3S)2·C4H4O4Purity:99.68% - 99.74%Color and Shape:SolidMolecular weight:885.23Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purity:100% - 99.89%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94Nicorandil
CAS:Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.Formula:C8H9N3O4Purity:98.14% - 99.44%Color and Shape:White Or Off-White PowderMolecular weight:211.17Sipatrigine
CAS:Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.Formula:C15H16Cl3N5Purity:100% - 99.49%Color and Shape:SolidMolecular weight:372.68Ref: TM-T16887
1mg96.00€5mg202.00€10mg303.00€25mg507.00€50mg730.00€100mg1,026.00€200mg1,378.00€1mL*10mM (DMSO)224.00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.92%Color and Shape:Light Yellow PowderMolecular weight:610.74TWIK-1/TREK-1-IN-3
CAS:TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.Formula:C19H27F3N2O2Purity:99.04%Color and Shape:SolidMolecular weight:372.43Alismol
CAS:Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used forFormula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35Mesoridazine Besylate
CAS:Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Formula:C27H32N2O4S3Purity:99.58%Color and Shape:SolidMolecular weight:544.75KCC2 Modulator-2
CAS:KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.Formula:C35H45N5O3Color and Shape:SolidMolecular weight:583.76Minoxidil
CAS:Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.Formula:C9H15N5OPurity:99.89% - 99.97%Color and Shape:Crystals From Methanol-Acetonitrile SolidMolecular weight:209.25Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56Atpenin A5
CAS:Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24Pimozide
CAS:Pimozide: antipsychotic that blocks type 2 dopamine, alpha-adrenergic, and 5-HT2 receptors, reducing tics and delusions.Formula:C28H29F2N3OPurity:100% - 99.85%Color and Shape:SolidMolecular weight:461.55QO-40
CAS:QO-40 is a KCNQ2/3 potassium channels activator.Formula:C18H11ClF3N3OPurity:99.57%Color and Shape:SolidMolecular weight:377.75Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formula:C18H19N3O4Purity:99.80%Color and Shape:SolidMolecular weight:341.36Kv2-IN-A1
CAS:Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.Formula:C20H17ClN4OSPurity:98.83%Color and Shape:SolidMolecular weight:396.89Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.8%Color and Shape:SolidMolecular weight:481.544-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:90%Color and Shape:SolidMolecular weight:94.11SKA-31
CAS:SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26BMS-191011
CAS:BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormula:C16H10ClF3N2O3Purity:97.43%Color and Shape:SolidMolecular weight:370.71Ebio3
Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Oxypeucedanin
CAS:1.Formula:C16H14O5Purity:98.66% - 98.85%Color and Shape:SolidMolecular weight:286.28Chlorahololide C
CAS:Chlorahololide C blocks potassium channels, selectively inhibiting I(K) current with an IC50 of 3.6±10.1 µM.Formula:C33H36O9Purity:98%Color and Shape:SolidMolecular weight:576.63VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFormula:C20H22ClFN4O2SPurity:97.91%Color and Shape:SoildMolecular weight:436.93Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Flindokalner
CAS:Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formula:C16H10ClF4NO2Purity:99.25%Color and Shape:SolidMolecular weight:359.7Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Formula:C22H31NO3Purity:100% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49MCHR1 antagonist 2
CAS:MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.Formula:C23H21FN2O5Purity:97.16%Color and Shape:SolidMolecular weight:424.42Ref: TM-T11966
1mg49.00€5mg104.00€10mg170.00€25mg369.00€50mg588.00€100mg944.00€1mL*10mM (DMSO)126.00€XE 991 dihydrochloride
CAS:XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Ref: TM-T16347
2mg34.00€5mg52.00€10mg85.00€25mg156.00€50mg245.00€100mg364.00€200mg517.00€1mL*10mM (DMSO)58.00€Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Ref: TM-T8125
5mg44.00€10mg55.00€25mg78.00€50mg99.00€100mg150.00€200mg219.00€500mg366.00€1mL*10mM (DMSO)65.00€Quinine
CAS:Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23VU591
CAS:1222810-74-3Formula:C16H12N6O5Purity:99.29% - 99.53%Color and Shape:SolidMolecular weight:368.3TRAM-34
CAS:TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.Formula:C22H17ClN2Purity:99.01% - 99.76%Color and Shape:SolidMolecular weight:344.8420(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:100% - 99.93%Color and Shape:SolidMolecular weight:785.01XE991
CAS:XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.Formula:C26H20N2OPurity:99.51%Color and Shape:SolidMolecular weight:376.45Ref: TM-T78570
1mg48.00€5mg96.00€10mg153.00€25mg283.00€50mg522.00€100mg838.00€500mg1,681.00€1mL*10mM (DMSO)105.00€Astemizole
CAS:Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Formula:C28H31FN4OPurity:98.24% - 99.67%Color and Shape:White Crystals SolidMolecular weight:458.57NS6180
CAS:NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Ref: TM-T1752
1mg35.00€2mg49.00€5mg70.00€10mg106.00€25mg225.00€50mg365.00€100mg545.00€1mL*10mM (DMSO)70.00€ML133 hydrochloride
CAS:ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82Ref: TM-T6592
5mg50.00€10mg66.00€25mg106.00€50mg170.00€100mg274.00€200mg354.00€500mg597.00€1mL*10mM (DMSO)52.00€Quinine dihydrochloride
CAS:Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formula:C20H26Cl2N2O2Purity:99.45% - 99.97%Color and Shape:White SolidMolecular weight:397.34Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.63%Color and Shape:SolidMolecular weight:366.46Dendrotoxin K TFA
Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].Formula:C294H462N84O75S6·XC2HF3OC2Purity:98%Color and Shape:SolidMolecular weight:6559.66 (free base)Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Ref: TM-T1073
5mg38.00€10mg52.00€25mg87.00€50mg117.00€100mg170.00€200mg250.00€500mg424.00€1mL*10mM (DMSO)55.00€Dimethindene
CAS:Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.Formula:C20H24N2Purity:99% - 99.44%Color and Shape:SolidMolecular weight:292.42C 101248
CAS:C 101248 (KCNK13-IN-1) is a selective and potent tandem pore halogen inhibitor of K+ channel 1 (THIK-1) inhibitor and a human and mouse KCNK13 inhibitor.Formula:C15H12N6OPurity:99.25% - 99.31%Color and Shape:SolidMolecular weight:292.3Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.50% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Reserpine hydrochloride
CAS:Reserpine hydrochloride inhibits the uptake of norepinephrine, depletion of catecholamines and serotonin in axon terminals, antihypertensive and antipsychotic.Formula:C33H41ClN2O9Purity:99.96%Color and Shape:SolidMolecular weight:645.14KS176
CAS:KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.Formula:C22H19N3O5Purity:99.55% - 99.78%Color and Shape:SolidMolecular weight:405.4Ref: TM-T3581
2mg34.00€5mg51.00€10mg86.00€25mg167.00€50mg305.00€100mg439.00€200mg615.00€1mL*10mM (DMSO)51.00€ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Formula:C17H23NOPurity:99.74%Color and Shape:SolidMolecular weight:257.37Cesium chloride
CAS:Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.Formula:ClCsPurity:98%Color and Shape:White Solid CrystallineMolecular weight:168.36Doxapram
CAS:Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.Formula:C24H30N2O2Purity:99.42%Color and Shape:SolidMolecular weight:378.51Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42Iptakalim Hydrochloride
CAS:Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormula:C9H22ClNPurity:95%Color and Shape:SolidMolecular weight:179.731Nateglinide
CAS:Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.Formula:C19H27NO3Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:317.42Paederosidic acid methyl ester
CAS:Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.Formula:C19H26O12SPurity:99.67% - 99.91%Color and Shape:SolidMolecular weight:478.47Gliquidone
CAS:Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity.Formula:C27H33N3O6SPurity:98.92% - 99.93%Color and Shape:SolidMolecular weight:527.63VU0134992
CAS:VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μMFormula:C20H31BrN2O2Purity:99.86%Color and Shape:SolidMolecular weight:411.38Ref: TM-T8372
1mg74.00€5mg138.00€10mg202.00€25mg340.00€50mg484.00€100mg667.00€200mg899.00€1mL*10mM (DMSO)164.00€ML 297
CAS:ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32TASK-1-IN-1
CAS:TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.Formula:C22H20N2O2Purity:100%Color and Shape:SoildMolecular weight:344.41APD668
CAS:APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formula:C21H24FN5O5SPurity:99.45% - 99.97%Color and Shape:SolidMolecular weight:477.51CLP257
CAS:CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.Formula:C14H14FN3O2SPurity:98.13%Color and Shape:SolidMolecular weight:307.34BMS-191095
CAS:BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.Formula:C22H21ClN4O2Purity:100%Color and Shape:SolidMolecular weight:408.88Ref: TM-T10566
1mg96.00€5mg202.00€10mg305.00€25mg550.00€50mg747.00€100mg1,008.00€1mL*10mM (DMSO)224.00€Butamben
CAS:Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formula:C11H15NO2Purity:99.43%Color and Shape:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Molecular weight:193.24(±)8(9)-EpETE
CAS:(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36Ref: TM-T10979
1mg35.00€5mg74.00€10mg114.00€25mg235.00€50mg465.00€100mg605.00€200mg852.00€1mL*10mM (DMSO)84.00€Yoda 1
CAS:Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.Formula:C13H8Cl2N4S2Purity:98% - 99.98%Color and Shape:SolidMolecular weight:355.27Ref: TM-T7506
1mg47.00€2mg60.00€5mg95.00€10mg115.00€25mg230.00€50mg447.00€100mg655.00€500mg1,388.00€1mL*10mM (DMSO)94.00€N-Acetylprocainamide
CAS:N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmicFormula:C15H23N3O2Purity:99.68% - 99.85%Color and Shape:SolidMolecular weight:277.36JNJ 303
CAS:JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98Ref: TM-T7653
1mg48.00€2mg65.00€5mg89.00€10mg147.00€25mg325.00€50mg472.00€100mg705.00€1mL*10mM (DMSO)92.00€GAL-021 sulfate
CAS:GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.Formula:C11H24N6O5SPurity:99.68%Color and Shape:SolidMolecular weight:352.41OR-1896
CAS:OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Formula:C13H15N3O2Purity:99.51%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12315
1mg92.00€2mg135.00€5mg216.00€10mg393.00€25mg847.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)240.00€Tolazamide
CAS:Tolazamide (U-17835) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Formula:C14H21N3O3SPurity:100% - 99.7%Color and Shape:SolidMolecular weight:311.4Ref: TM-T1333
2mg35.00€5mg52.00€10mg70.00€25mg97.00€50mg125.00€100mg160.00€200mg230.00€1mL*10mM (DMSO)62.00€Zacopride hydrochloride
CAS:Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.Formula:C15H20ClN3O2·HClPurity:98.32%Color and Shape:SolidMolecular weight:346.26Ref: TM-T5336
1mg46.00€5mg87.00€10mg144.00€25mg283.00€50mg454.00€100mg655.00€200mg930.00€1mL*10mM (DMSO)97.00€RL648_81
CAS:RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.Formula:C17H17F4N3O2Purity:98.85%Color and Shape:SolidMolecular weight:371.33Ref: TM-T28544
2mg44.00€5mg64.00€10mg105.00€25mg226.00€50mg335.00€100mg480.00€200mg652.00€1mL*10mM (DMSO)77.00€Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.83KCNQ2/3 activator-1
CAS:KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.Formula:C23H29FN2OPurity:98.99% - 99.16%Color and Shape:SolidMolecular weight:368.49Ref: TM-T9400
2mg40.00€5mg62.00€10mg94.00€25mg153.00€50mg235.00€100mg373.00€500mg938.00€1mL*10mM (DMSO)67.00€Talatisamine
CAS:Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formula:C24H39NO5Purity:98.62% - 99.44%Color and Shape:SolidMolecular weight:421.57Taurocholic acid sodium salt hydrate
CAS:Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is the product of conjugation of taurine with cholic acid.Formula:C26H44NNaO7S·xH2OPurity:99.26% - ≥98%Color and Shape:SolidMolecular weight:537.68Glimepiride
CAS:Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Formula:C24H34N4O5SPurity:97.84% - 98.49%Color and Shape:White Cyrstalline SolidMolecular weight:490.62Maralixibat Chloride
CAS:Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.Formula:C40H56ClN3O4SPurity:100.00% - 98.36%Color and Shape:SolidMolecular weight:710.41Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88NS 11021
CAS:NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormula:C16H9BrF6N6SPurity:97%Color and Shape:SolidMolecular weight:511.24DMP-543
CAS:DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.Formula:C26H18F2N2OPurity:100%Color and Shape:SolidMolecular weight:412.43ZTZ240
CAS:ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.Formula:C12H8ClFN2OPurity:99.93%Color and Shape:SolidMolecular weight:250.66Almokalant
CAS:Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Bisaramil hydrochloride
CAS:Bisaramil hydrochloride (Bisaramil) is an antiarrhythmic compound that inhibits free radical production.Formula:C17H24Cl2N2O2Purity:98.90% - 99.64%Color and Shape:SolidMolecular weight:359.29ICA-27243
CAS:ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.Formula:C12H7ClF2N2OPurity:99.54%Color and Shape:SolidMolecular weight:268.65
