Proton pump
Proton pumps are membrane proteins that actively transport protons (H+) across the cell membrane or organelle membranes, creating a proton gradient that is essential for various cellular processes. The most well-known proton pump is the H+/K+ ATPase, found in the stomach lining, which is responsible for acid secretion. Proton pumps are also critical in cellular respiration and pH regulation. Dysregulation of proton pump activity is associated with conditions such as acid reflux, ulcers, and metabolic acidosis. At CymitQuimica, we provide a selection of proton pump inhibitors and modulators to support your research in gastroenterology, metabolism, and cellular bioenergetics.
Products of "Proton pump"
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Found 41 products on this category.
Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Diphyllin
CAS:Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.Formula:C21H16O7Purity:99.91% - 99.98%Color and Shape:SolidMolecular weight:380.35Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35V-ATPase-IN-1
CAS:V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.Formula:C21H20ClNO2Color and Shape:SolidMolecular weight:353.84Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.63%Color and Shape:SolidMolecular weight:366.46Rabeprazole Sulfide
CAS:Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.Formula:C18H21N3O2SPurity:99.34% - 99.80%Color and Shape:Off-White Crystalline PowderMolecular weight:343.44Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Formula:C10H8N2O2S2ZnPurity:99.47% - 99.64%Color and Shape:Off-White To Tan PowderMolecular weight:317.71Ilaprazole sodium hydrate
CAS:Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.Formula:C19H21N4NaO4SPurity:99.2%Color and Shape:SolidMolecular weight:424.45ATP4A Protein, Human, Recombinant (His & Myc)
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:54.6 kDa (predicted)Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42Esomeprazole Sodium
CAS:Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Formula:C17H18N3O3S·NaPurity:100% - 98.17%Color and Shape:SolidMolecular weight:367.4Pumaprazole
CAS:Pumaprazole (BY-841) is an antagonist of a reversible proton pump.Formula:C19H22N4O2Purity:99.6%Color and Shape:SolidMolecular weight:338.4Ref: TM-T16682
1mg92.00€5mg188.00€10mg311.00€25mg635.00€50mg1,017.00€100mg1,644.00€200mg2,213.00€1mL*10mM (DMSO)215.00€Ilaprazole sodium
CAS:Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.Formula:C19H17N4NaO2SPurity:99.06%Color and Shape:SolidMolecular weight:388.42Ref: TM-T1756
1mg37.00€2mg52.00€5mg77.00€10mg92.00€25mg188.00€50mg305.00€100mg487.00€1mL*10mM (DMSO)79.00€Levolansoprazole
CAS:Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM).Formula:C16H14F3N3O2SPurity:98.62%Color and Shape:SolidMolecular weight:369.36Ref: TM-T20714
1mg135.00€2mg188.00€5mg329.00€10mg467.00€25mg677.00€50mg929.00€100mg1,244.00€200mg1,681.00€1mL*10mM (DMSO)331.00€Esomeprazole Magnesium trihydrate
CAS:Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophagealFormula:C34H42MgN6O9S2Purity:98.52%Color and Shape:Off-White PowderMolecular weight:767.17Bamaquimast
CAS:Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.Formula:C16H21N3O3Purity:98.40%Color and Shape:SolidMolecular weight:303.36WY-47766
CAS:WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.Formula:C14H13N3O2SPurity:98.11% - 99.75%Color and Shape:SolidMolecular weight:287.34Vonoprazan
CAS:Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer andFormula:C17H16FN3O2SPurity:99.92%Color and Shape:SolidMolecular weight:345.39Esomeprazole
CAS:Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.Formula:C17H19N3O3SPurity:98.20%Color and Shape:SolidMolecular weight:345.42Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:99.28% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.375-Hydroxylansoprazole
CAS:5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.Formula:C16H14F3N3O3SPurity:99.00%Color and Shape:SolidMolecular weight:385.36KM 91104
CAS:KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.Formula:C14H12N2O4Purity:99.04%Color and Shape:SolidMolecular weight:272.26Ref: TM-T9230
1mg88.00€5mg169.00€10mg259.00€25mg520.00€50mg753.00€100mg1,035.00€500mg2,110.00€1mL*10mM (DMSO)234.00€Thonzonium Bromide
CAS:Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).Formula:C32H55BrN4OPurity:98.48% - 99.94%Color and Shape:SolidMolecular weight:591.71Saviprazole
CAS:Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.Formula:C15H10F7N3O2S2Purity:97.07% - 97.73%Color and Shape:SolidMolecular weight:461.38(R)-Lansoprazole
CAS:(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitorFormula:C16H14F3N3O2SPurity:98.09% - 98.99%Color and Shape:Brown SolidMolecular weight:369.36Abscisic Acid
CAS:Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.Formula:C15H20O4Purity:99.60% - 99.64%Color and Shape:White PowderMolecular weight:264.32Tenatoprazole
CAS:Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).Formula:C16H18N4O3SPurity:99.57%Color and Shape:White Crystalline PowderMolecular weight:346.4Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.57%Color and Shape:Clear In WaterMolecular weight:367.4Abeprazan hydrochloride
CAS:Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPaseFormula:C19H18ClF3N2O3SPurity:98.62%Color and Shape:SolidMolecular weight:446.87Tegoprazan
CAS:Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.Formula:C20H19F2N3O3Purity:98.22%Color and Shape:SolidMolecular weight:387.38Ref: TM-T17030
1mg52.00€5mg120.00€10mg180.00€25mg298.00€50mg393.00€100mg512.00€200mg727.00€1mL*10mM (DMSO)133.00€Ilaprazole
CAS:Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.Formula:C19H18N4O2SPurity:99.08%Color and Shape:SolidMolecular weight:366.44Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.4% - 99.54%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg73.00€5mg155.00€10mg219.00€25mg465.00€50mg692.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)266.00€S-Pantoprazole sodium trihydrate
CAS:S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as aFormula:C16H20F2N3NaO7SPurity:98%Color and Shape:SolidMolecular weight:459.4Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurity:99.18% - 99.84%Color and Shape:White Crystalline PowderMolecular weight:369.36EN6
CAS:EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formula:C19H14F2N4O2Purity:95.16% - 97.04%Color and Shape:SolidMolecular weight:368.34Ref: TM-T11191
1mg47.00€5mg88.00€10mg137.00€25mg205.00€50mg264.00€100mg400.00€500mg909.00€1mL*10mM (DMSO)70.00€Vonoprazan Fumarate
CAS:Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.Formula:C21H20FN3O6SPurity:≥98%Color and Shape:SolidMolecular weight:461.46Omeprazole metabolite Omeprazole sulfone
CAS:Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.Formula:C17H19N3O4SPurity:99.61%Color and Shape:SolidMolecular weight:361.42Ref: TM-T12309
1mg49.00€2mg65.00€5mg97.00€10mg154.00€25mg298.00€50mg445.00€100mg642.00€500mg1,320.00€1mL*10mM (DMSO)120.00€Esomeprazole Magnesium
CAS:Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Formula:C34H36MgN6O6S2Purity:98.76% - 98.84%Color and Shape:SolidMolecular weight:713.12Pantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormula:C16H14F2N3NaO4SH2OPurity:98.32%Color and Shape:SolidMolecular weight:432.37Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurity:98% - 99.36%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42Omeprazole sulfide
CAS:Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.Formula:C17H19N3O2SPurity:98.83%Color and Shape:White To Slightly Collored Solid Solid CrystallineMolecular weight:329.42
