GABA Receptor
GABA receptors are the primary inhibitory neurotransmitter receptors in the central nervous system, playing a critical role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. GABA receptor dysfunction is implicated in various neurological and psychiatric disorders, including epilepsy, anxiety, and depression. At CymitQuimica, we provide a comprehensive range of GABA receptor modulators to support your research in neurobiology, mental health, and therapeutic development.
Products of "GABA Receptor"
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Kavain
CAS:Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation ofFormula:C14H14O3Purity:99.35% - ≥95%Color and Shape:SolidMolecular weight:230.26Radequinil
CAS:Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).Formula:C18H14N4O3Purity:98%Color and Shape:SolidMolecular weight:334.33Riluzole
CAS:Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.Formula:C8H5F3N2OSPurity:99.71% - 99.88%Color and Shape:PowderMolecular weight:234.2Phenibut (hydrochloride)
CAS:Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors.Formula:C10H14ClNO2Purity:99.93%Color and Shape:White Crystalline PowderMolecular weight:215.68Chlormezanone
CAS:Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.Formula:C11H12ClNO3SPurity:99.89% - 99.97%Color and Shape:Crystals SolidMolecular weight:273.74Chlorothymol
CAS:Chlorothymol (AI3-00120) is a disinfectant used in oral.Formula:C10H13ClOPurity:99.50%Color and Shape:White Crystals Or PowderMolecular weight:184.66Ref: TM-T20242
5mg48.00€10mg66.00€25mg97.00€50mg154.00€100mg216.00€200mg324.00€500mg543.00€1mL*10mM (DMSO)48.00€Saclofen
CAS:Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Formula:C9H12ClNO3SPurity:99.17%Color and Shape:White Crystalline SolidMolecular weight:249.71(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.Formula:C21H20ClNO6Purity:98%Color and Shape:SolidMolecular weight:417.84Tuclazepam
CAS:Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.Formula:C17H16Cl2N2OColor and Shape:SolidMolecular weight:335.23Brexanolone caprilcerbate
CAS:Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formula:C48H78O12Color and Shape:SolidMolecular weight:847.13Temgicoluril
CAS:Temgicoluril (mebikar) acts on GABA Receptor.Formula:C8H14N4O2Purity:99.80%Color and Shape:SolidMolecular weight:198.22Darigabat
CAS:Darigabat (PF-06372865) is a GABAA receptor modulator with anxiolytic activity that inhibits α2, α1 PAM, and α2 PAM.Formula:C22H21FN4O3SPurity:98.42% - 99.29%Color and Shape:SolidMolecular weight:440.49ELB-139
CAS:ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.Formula:C14H16ClN3OPurity:100%Color and Shape:SolidMolecular weight:277.75Ru-32514
CAS:Ru-32514 is a benzodiazepine receptor agonist.Formula:C18H17N3O2Purity:98.74%Color and Shape:SolidMolecular weight:307.35TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Formula:C20H22FN7OPurity:99.06%Color and Shape:SolidMolecular weight:395.43Ref: TM-T17144
1mg227.00€5mg550.00€10mg825.00€25mg1,216.00€50mg1,644.00€100mg2,213.00€1mL*10mM (DMSO)605.00€2'-O-Methylisoliquiritigenin
CAS:2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-Formula:C16H14O4Purity:98.75%Color and Shape:SolidMolecular weight:270.28GABAB receptor antagonist 1
CAS:(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selectiveFormula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38rac-BHFF
CAS:rac-BHFF, a GABA B receptor modulator, boosts GABA potency >15x, efficacy >149%, has anxiolytic effects, and is orally active.Formula:C17H21F3O3Purity:100% - 98.43%Color and Shape:SolidMolecular weight:330.34Ref: TM-T4176
2mg43.00€5mg60.00€10mg96.00€25mg187.00€50mg311.00€100mg472.00€200mg657.00€1mL*10mM (DMSO)71.00€COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.56%Color and Shape:SolidMolecular weight:337.82Ref: TM-T36520
1mg52.00€2mg75.00€5mg116.00€10mg178.00€25mg324.00€50mg452.00€100mg620.00€200mg843.00€1mL*10mM (DMSO)128.00€Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:100%Color and Shape:SolidMolecular weight:352.73Cirsimaritin
CAS:Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.Formula:C17H14O6Purity:99.59%Color and Shape:SolidMolecular weight:314.29Afoxolaner
CAS:Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.Formula:C26H17ClF9N3O3Purity:99.10% - 99.38%Color and Shape:SolidMolecular weight:625.87E2730
CAS:E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Formula:C9H8F4N2O2SPurity:98.22% - 98.54%Color and Shape:SolidMolecular weight:284.23AZD 3043
CAS:AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Formula:C19H29NO5Purity:98.19% - ≥98%Color and Shape:SolidMolecular weight:351.44Alpidem
CAS:Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.Formula:C21H23Cl2N3OPurity:100% - 99.49%Color and Shape:White To Off-White SolidMolecular weight:404.33TP003
CAS:TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.Formula:C23H16F3N3OPurity:98.00%Color and Shape:SolidMolecular weight:407.39Lirequinil
CAS:Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Formula:C26H25ClN2O3Purity:98.06%Color and Shape:SolidMolecular weight:448.94CL 218872
CAS:CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.Formula:C13H9F3N4Purity:99.92%Color and Shape:SolidMolecular weight:278.233-Methylglutaconic acid
CAS:3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:144.13Acamprosate calcium
CAS:Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.Formula:C10H20CaN2O8S2Purity:98% - 99.93%Color and Shape:White Odorless Or Nearly Odorless PowderMolecular weight:400.48(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16Pazinaclone
CAS:Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.Formula:C25H23ClN4O4Purity:98.12% - 99%Color and Shape:SolidMolecular weight:478.93Suritozole
CAS:Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptorFormula:C10H10FN3SPurity:99.25%Color and Shape:SolidMolecular weight:223.27Ref: TM-T8568
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)158.00€Pipequaline
CAS:Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.Formula:C22H24N2Purity:98%Color and Shape:SolidMolecular weight:316.44Acetoxyvalerensre
CAS:Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.Formula:C17H24O4Purity:98.22%Color and Shape:SolidMolecular weight:292.37Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36NO 711
CAS:NO 711(NNC-711 free acid) is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.Formula:C21H22N2O3Purity:99.83%Color and Shape:SolidMolecular weight:350.41Bicuculline
CAS:Bicuculline, a plant-derived GABAA receptor antagonist, identified in 1932, reacts to light.Formula:C20H17NO6Purity:98% - ≥98%Color and Shape:Light Yellow PowderMolecular weight:367.35Loreclezole
CAS:Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.Formula:C10H6Cl3N3Purity:99.78%Color and Shape:SolidMolecular weight:274.53GABA-IN-4
CAS:GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.Formula:C17H13ClN2O2Color and Shape:SolidMolecular weight:312.75Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormula:C8H16O2·C8H15O2·NaPurity:99.84%Color and Shape:A White Powder With A Characteristic OdorMolecular weight:310.41Ref: TM-T6474
10mg39.00€25mg55.00€50mg79.00€100mg116.00€200mg188.00€500mg335.00€1mL*10mM (DMSO)55.00€Progabide
CAS:Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.Formula:C17H16ClFN2O2Purity:99.7%Color and Shape:SolidMolecular weight:334.77Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.17Etifoxine hydrochloride
CAS:Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.Formula:C17H18Cl2N2OPurity:99.36%Color and Shape:SolidMolecular weight:337.24Panadiplon
CAS:Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment ofFormula:C18H17N5O2Purity:100% - 99.75%Color and Shape:SolidMolecular weight:335.36L-838417
CAS:L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disordersFormula:C19H19F2N7OPurity:98.12% - 99.82%Color and Shape:SolidMolecular weight:399.4Pivagabine
CAS:Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.Formula:C9H17NO3Purity:99.87%Color and Shape:SolidMolecular weight:187.24Ref: TM-T12492
1mg35.00€2mg48.00€5mg70.00€10mg104.00€25mg167.00€50mg249.00€100mg369.00€500mg837.00€1mL*10mM (DMSO)50.00€Bifenazate
CAS:Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.Formula:C17H20N2O3Purity:99.44%Color and Shape:Solid CrystallineMolecular weight:300.35Thiocolchicoside
CAS:Thiocolchicoside, a muscle relaxant, has anti-inflammatory and analgesic properties; not for seizure-prone people.Formula:C27H33NO10SPurity:99.11% - 99.39%Color and Shape:SolidMolecular weight:563.62Xilmenolone
CAS:Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59
