GABA Receptor
GABA receptors are the primary inhibitory neurotransmitter receptors in the central nervous system, playing a critical role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. GABA receptor dysfunction is implicated in various neurological and psychiatric disorders, including epilepsy, anxiety, and depression. At CymitQuimica, we provide a comprehensive range of GABA receptor modulators to support your research in neurobiology, mental health, and therapeutic development.
Products of "GABA Receptor"
Sort by
Suriclone
CAS:Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.Formula:C20H20ClN5O3S2Purity:98.17% - 98.52%Color and Shape:SolidMolecular weight:477.99BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFormula:C19H20Cl2N2OPurity:99.24% - 99.86%Color and Shape:SolidMolecular weight:363.28Ref: TM-T26891
5mg40.00€10mg58.00€25mg109.00€50mg170.00€100mg273.00€200mg378.00€1mL*10mM (DMSO)78.00€Dipropofol
CAS:Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.Formula:C24H34O2Purity:99.6%Color and Shape:SolidMolecular weight:354.53AZD-6280
CAS:AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.Formula:C20H22N4O3Purity:98.99%Color and Shape:SolidMolecular weight:366.41Ref: TM-T7136
1mg227.00€5mg464.00€10mg677.00€25mg1,074.00€50mg1,501.00€100mg2,043.00€1mL*10mM (DMSO)510.00€DL-Menthol
CAS:DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (-)-menthol and (+)-menthod, which have been found in Cannabis.Formula:C10H20OPurity:99.74%Color and Shape:White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Molecular weight:156.27Methionine
CAS:Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptorFormula:C5H11NO2SPurity:99.13% - 99.62%Color and Shape:SolidMolecular weight:149.21Basmisanil
CAS:Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for theFormula:C21H20FN3O5SPurity:99.21% - ≥98%Color and Shape:SolidMolecular weight:445.46Ref: TM-T7165
2mg38.00€5mg56.00€10mg79.00€25mg123.00€50mg197.00€100mg376.00€500mg847.00€1mL*10mM (DMSO)52.00€Riluzole hydrochloride
CAS:Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).Formula:C8H6ClF3N2OSPurity:99.76%Color and Shape:SolidMolecular weight:270.66Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01(E)-3,4,5-Trimethoxycinnamic acid
CAS:(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.Formula:C12H14O5Purity:99.83%Color and Shape:SolidMolecular weight:238.24GS 39783
CAS:GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement andFormula:C15H23N5O2SPurity:99.94%Color and Shape:SolidMolecular weight:337.44Isonipecotic acid
CAS:Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.Formula:C6H11NO2Purity:99.82%Color and Shape:White To Faint Pink-Beige PowderMolecular weight:129.16Piperazine citrate
CAS:Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.Formula:C24H46N6O14Purity:≥98%Color and Shape:Crystals IndicationMolecular weight:642.65Lorediplon
CAS:Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.Formula:C20H15FN4O2SPurity:99.12% - 99.19%Color and Shape:SolidMolecular weight:394.42L-655708
CAS:L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.Formula:C18H19N3O4Purity:98.41%Color and Shape:PowderMolecular weight:341.36U 89843A
CAS:U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Formula:C16H23N5Purity:99.53%Color and Shape:SolidMolecular weight:285.39Arecaidine hydrochloride
CAS:Arecaidine hydrochloride may have carcinogenesis.Formula:C7H12ClNO2Purity:≥95% - ≥98%Color and Shape:SolidMolecular weight:177.63Ref: TM-T5799
2mg35.00€5mg50.00€10mg71.00€25mg105.00€50mg158.00€100mg225.00€200mg334.00€1mL*10mM (DMSO)51.00€Nerisopam
CAS:Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.Formula:C18H19N3O2Purity:97.27%Color and Shape:SolidMolecular weight:309.36Ref: TM-T28159
1mg93.00€5mg200.00€10mg303.00€25mg490.00€50mg710.00€100mg998.00€200mg1,349.00€1mL*10mM (DMSO)270.00€ONO-8590580
CAS:ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.Formula:C21H21FN6Purity:99.43%Color and Shape:SolidMolecular weight:376.43Ref: TM-TQ0040
1mg66.00€2mg93.00€5mg126.00€10mg170.00€25mg376.00€50mg562.00€100mg802.00€1mL*10mM (DMSO)140.00€SKF89976A hydrochloride
CAS:SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) andFormula:C22H26ClNO2Purity:98.72%Color and Shape:SolidMolecular weight:371.9Ref: TM-T12930
1mg35.00€5mg69.00€10mg95.00€25mg178.00€50mg283.00€100mg454.00€200mg650.00€1mL*10mM (DMSO)74.00€4-Acetamidobutanoic acid
CAS:4-Acetamidobutanoic acid, a GABA derivative in eukaryotes, found in blood, feces, urine, and human prostate.Formula:C6H11NO3Purity:99.79%Color and Shape:SolidMolecular weight:145.16U-89843A
CAS:U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].Formula:C16H24ClN5Purity:98%Color and Shape:SolidMolecular weight:321.85Broflanilide
CAS:Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.Formula:C25H14BrF11N2O2Purity:98.95%Color and Shape:SolidMolecular weight:663.29Ref: TM-T10618
1mg52.00€2mg74.00€5mg111.00€10mg180.00€25mg358.00€50mg588.00€100mg835.00€1mL*10mM (DMSO)131.00€Tracazolate hydrochloride
CAS:Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Formula:C16H25ClN4O2Purity:99.07%Color and Shape:SolidMolecular weight:340.85GABA receptor Antagonist 1
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.Purity:98%Color and Shape:Odour Solid6-(4-Methoxyphenyl)-3-pyridazinamine
CAS:6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonistFormula:C11H11N3OPurity:99.03%Color and Shape:SolidMolecular weight:201.22TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.36PZ-II-029
CAS:PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.Formula:C18H15N3O3Purity:99.72%Color and Shape:SolidMolecular weight:321.33Ref: TM-T28479
1mg52.00€5mg111.00€10mg170.00€25mg305.00€50mg472.00€100mg723.00€500mg1,454.00€1mL*10mM (DMSO)202.00€(R)-baclofen
CAS:(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.Formula:C10H12ClNO2Purity:98.94%Color and Shape:SolidMolecular weight:213.66NS-2710
CAS:NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.Formula:C22H20N4OPurity:98.10% - 99.82%Color and Shape:SolidMolecular weight:356.42NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formula:C22H24N2O3Purity:96.14%Color and Shape:SolidMolecular weight:364.44Ref: TM-T24540
1mg87.00€2mg124.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)202.00€LAU159
CAS:LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).Formula:C17H12ClN3O2Purity:98.70% - 99.38%Color and Shape:SolidMolecular weight:325.75Ref: TM-T11822
1mg116.00€2mg169.00€5mg230.00€10mg418.00€25mg690.00€50mg938.00€100mg1,311.00€500mg2,632.00€3α,21-Dihydroxy-5α-pregnan-20-one
CAS:3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.Formula:C21H34O3Purity:98.00%Color and Shape:SolidMolecular weight:334.49Rilmazolam
CAS:Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.Formula:C19H15Cl2N5OColor and Shape:SolidMolecular weight:400.262'MeO6MF
CAS:2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functionalFormula:C17H14O3Purity:99.28% - 99.63%Color and Shape:SolidMolecular weight:266.29Ref: TM-T8887
1mg51.00€5mg107.00€10mg160.00€25mg255.00€50mg359.00€100mg485.00€200mg662.00€1mL*10mM (DMSO)101.00€Tiagabine
CAS:Tiagabine (NO050328) is an Anti-epileptic Agent.Formula:C20H25NO2S2Purity:99.24%Color and Shape:White To Off-White Crystalline SolidMolecular weight:375.55MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23Propanidid
CAS:Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.Formula:C18H27NO5Purity:99.39%Color and Shape:SolidMolecular weight:337.41Ref: TM-T34146
1mg43.00€5mg85.00€10mg106.00€25mg173.00€50mg255.00€100mg373.00€200mg550.00€500mg803.00€Songorine
CAS:Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.Formula:C22H31NO3Purity:98% - 99.92%Color and Shape:SolidMolecular weight:357.49(2S)-6-Prenylnaringenin
CAS:(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.Formula:C20H20O5Purity:99.47%Color and Shape:SolidMolecular weight:340.37Amentoflavone
CAS:Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Formula:C30H18O10Purity:98.21% - 99.22%Color and Shape:Odourless Whitish SolidMolecular weight:538.46SCS
CAS:SCS is a GABAA receptor antagonist.Formula:C14H12N2O3Purity:98.89%Color and Shape:SolidMolecular weight:256.26Fengabine
CAS:Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.Formula:C17H17Cl2NOPurity:98.54%Color and Shape:SolidMolecular weight:322.23Desmethylflunitrazepam
CAS:Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.Formula:C15H10FN3O3Color and Shape:SolidMolecular weight:299.26Vigabatrin Hydrochloride
CAS:Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Formula:C6H11NO2·HClPurity:98%Color and Shape:SolidMolecular weight:165.62Pentetrazol
CAS:Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.Formula:C6H10N4Purity:100% - 99.95%Color and Shape:Bitter Taste Aqueous Solutions Neutral To Litmus (Ntp 1992)Molecular weight:138.17(R)-Baclofen hydrochloride
CAS:Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.Formula:C10H13Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:250.12L-DABA hydrobromide
CAS:L-DABA hydrobromide (L-2,4-Diaminobutyric acid hydrobromide) , GABA transaminase inhibitor with antitumor and anticonvulsant activity.Formula:C4H11BrN2O2Purity:99.11%Color and Shape:SolidMolecular weight:199.05GABAA receptor agent 1
CAS:GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.Formula:C13H8ClN3O2Purity:99.31%Color and Shape:SolidMolecular weight:273.67Ref: TM-T11349
1mg38.00€5mg84.00€10mg117.00€25mg226.00€50mg340.00€100mg495.00€200mg682.00€1mL*10mM (DMSO)90.00€Imidazenil
CAS:Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.Formula:C18H12BrFN4OPurity:98.4%Color and Shape:SolidMolecular weight:399.22
