PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Products of "PDE"
Sort by
Propentofylline
CAS:Propentofylline (Hextol) has neuroprotective, antiproliferative and anti-inflammatory activities and can be used in the study of Alzheimer's disease.Formula:C15H22N4O3Purity:99.11% - 99.42%Color and Shape:Off-White SolidMolecular weight:306.36Ref: TM-T19812
1mg69.00€5mg145.00€10mg212.00€25mg358.00€50mg527.00€100mg750.00€1mL*10mM (DMSO)157.00€cis-Tadalafil
CAS:Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.Formula:C22H19N3O4Purity:≥98%Color and Shape:SolidMolecular weight:389.4Anti-ALDH7A1 Antibody (3P955)
Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidThioquinapiperifil dihydrochloride
CAS:Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Formula:C24H29ClN6OSPurity:98.73%Color and Shape:SolidMolecular weight:485.05Ref: TM-T9773
1mg84.00€5mg178.00€10mg266.00€25mg434.00€50mg562.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)205.00€Homo Sildenafil
CAS:Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.Formula:C23H32N6O4SPurity:99.88%Color and Shape:White SolidMolecular weight:488.6Ref: TM-T8919
2mg42.00€5mg64.00€10mg92.00€25mg187.00€50mg281.00€100mg393.00€200mg552.00€1mL*10mM (DMSO)78.00€Ketotifen fumarate
CAS:Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.Formula:C23H23NO5SPurity:99.25% - 99.73%Color and Shape:SolidMolecular weight:425.5Mardepodect
CAS:Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.Formula:C25H20N4OPurity:98.82% - 99.81%Color and Shape:SolidMolecular weight:392.45Ref: TM-T16499
1mg43.00€2mg55.00€5mg92.00€10mg150.00€25mg245.00€50mg365.00€100mg547.00€1mL*10mM (DMSO)92.00€Lirimilast
CAS:Lirimilast: oral PDE4 inhibitor (IC50: 49 nM), anti-inflammatory, treats asthma/COPD.Formula:C17H12Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:443.26PDE10-IN-1
CAS:PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.Formula:C21H19N7Purity:99.65%Color and Shape:SolidMolecular weight:369.42N-Methylbenzamide
CAS:N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.Formula:C8H9NOPurity:99.83%Color and Shape:Physical Description Off-White Crystalline Solid (Ntp 1992)Molecular weight:135.16Anti-ALDH7A1 Antibody (5P692)
Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.Color and Shape:Odour LiquidBAY 73-6691
CAS:BAY 73-6691 is an inhibitor of brain penetrant PDE9A.Formula:C15H12ClF3N4OColor and Shape:SolidMolecular weight:356.73Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Formula:C22H28BrN5O5Purity:98.64% - 99.16%Color and Shape:SolidMolecular weight:522.39Amino Tadalafil
CAS:Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.Formula:C21H18N4O4Purity:99.45%Color and Shape:White PowderMolecular weight:390.39TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurity:98%Color and Shape:SolidMolecular weight:310.35ATX inhibitor 1
CAS:ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).Formula:C21H23Cl2N2O6PPurity:99.52%Color and Shape:SolidMolecular weight:501.3PF-8380
CAS:PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).Formula:C22H21Cl2N3O5Purity:98.70% - 99.25%Color and Shape:SolidMolecular weight:478.33Vardenafil
CAS:Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.Formula:C23H32N6O4SPurity:99.88%Color and Shape:SolidMolecular weight:488.6Nauclefine
CAS:Nauclefine, a plant alkaloid, triggers cancer cell death through PDE3A-SLFN12, binding but not inhibiting PDE3A.Formula:C18H13N3OPurity:99.92%Color and Shape:SolidMolecular weight:287.32BAY 73-6691 racemate
CAS:BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.Formula:C15H12ClF3N4OColor and Shape:SolidMolecular weight:356.73Autotaxin-IN-1
CAS:Autotaxin-IN-1: strong inhibitor for osteoarthritis pain; IC50=2.2 nM; good PK and PK/PD.Formula:C21H23N7O2Purity:98%Color and Shape:SolidMolecular weight:405.45NSP-805
CAS:NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.Formula:C17H19N3O2Purity:99.10%Color and Shape:SolidMolecular weight:297.35Ref: TM-T12267
1mg52.00€5mg116.00€10mg187.00€25mg325.00€50mg467.00€100mg645.00€200mg872.00€1mL*10mM (DMSO)128.00€MK-8189
CAS:MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.Formula:C19H22N6OSPurity:100% - 99.67%Color and Shape:SolidMolecular weight:382.48Tovinontrine
CAS:Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.Formula:C21H26N6O2Purity:98.14%Color and Shape:SolidMolecular weight:394.47FCPR03
CAS:FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.Formula:C15H19F2NO3Purity:100.00%Color and Shape:SolidMolecular weight:299.31Ref: TM-T39341
1mg52.00€2mg75.00€5mg116.00€10mg183.00€25mg311.00€50mg444.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)128.00€T-0156
CAS:T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.Formula:C31H29N5O7Purity:100% - 98.42%Color and Shape:SoildMolecular weight:583.59Deltasonamide 2
CAS:Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.Formula:C30H39ClN6O4S2Purity:98%Color and Shape:SolidMolecular weight:647.25Imazodan
CAS:Imazodan is a compound with positive inotropic activity and is a type III phosphodiesterase inhibitor that can be used to study heart failure.Formula:C13H12N4OPurity:98.56% - 99.36%Color and Shape:SolidMolecular weight:240.26Imazodan hydrochloride
CAS:Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure.Formula:C13H13ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:276.72Roflumilast
CAS:Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potentialFormula:C17H14Cl2F2N2O3Purity:100.00% - 99.76%Color and Shape:SolidMolecular weight:403.21BRL-50481
CAS:BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.Formula:C9H12N2O4SPurity:99.66%Color and Shape:SolidMolecular weight:244.27Autotaxin-IN-3
CAS:Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.Formula:C22H21N9O2Purity:98.49% - 99.21%Color and Shape:SolidMolecular weight:443.46Ref: TM-T10415
2mg46.00€5mg70.00€10mg101.00€25mg183.00€50mg284.00€100mg455.00€200mg625.00€1mL*10mM (DMSO)78.00€GEBR-7b
CAS:GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.Formula:C13H16O3Purity:99.54%Color and Shape:SolidMolecular weight:220.26PDE5-IN-2
CAS:PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)Formula:C25H21N3O6SPurity:98%Color and Shape:SolidMolecular weight:491.52Gisadenafil
CAS:Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.Formula:C23H33N7O5SPurity:98.25% - 99.06%Color and Shape:SolidMolecular weight:519.62Ref: TM-T15381
1mg185.00€5mg415.00€10mg613.00€25mg938.00€50mg1,311.00€100mg1,768.00€1mL*10mM (DMSO)520.00€Pumafentrine
CAS:Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.Formula:C29H39N3O3Purity:99.79%Color and Shape:SolidMolecular weight:477.64PF-05085727
CAS:PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.Formula:C20H18F3N7Purity:98%Color and Shape:SolidMolecular weight:413.4OPC18750 HCl
CAS:OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.Formula:C20H23ClN2O4Purity:98.92%Color and Shape:SoildMolecular weight:390.86Ref: TM-T83974
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€1mL*10mM (DMSO)47.00€[11C]MP 10
CAS:[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.Formula:C25H20N4OPurity:99.87%Color and Shape:SolidMolecular weight:391.45YM976
CAS:YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)Formula:C17H16ClN3OPurity:99.84%Color and Shape:SolidMolecular weight:313.78PF-00489791
CAS:PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.Formula:C20H28N8O4SPurity:100%Color and Shape:SolidMolecular weight:476.55K134
CAS:K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.Formula:C22H29N3O4Purity:98%Color and Shape:SolidMolecular weight:399.48WAY127093B racemate
CAS:WAY127093B racemate is the racemate of WAY127093B. WAY127093B is a phosphodiesterase IV inhibitor with oral activity in rats and guinea pigs.Formula:C23H28N4O4Purity:98.63%Color and Shape:SolidMolecular weight:424.49Ref: TM-T13331
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)170.00€Avanafil
CAS:Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.Formula:C23H26ClN7O3Purity:98% - 99.03%Color and Shape:White SolidMolecular weight:483.95Cilomilast
CAS:Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.Formula:C20H25NO4Purity:97.37% - 99.43%Color and Shape:White SolidMolecular weight:343.42PF-04957325
CAS:PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.Formula:C14H15F3N8OSPurity:99.02%Color and Shape:SolidMolecular weight:400.38Ref: TM-T12422
1mg137.00€5mg235.00€10mg354.00€25mg610.00€50mg885.00€100mg1,320.00€1mL*10mM (DMSO)207.00€MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Formula:C19H16Cl3FN4OPurity:98.09% - 98.94%Color and Shape:SolidMolecular weight:441.71Ref: TM-T12103
1mg145.00€2mg207.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€500mg3,125.00€1mL*10mM (DMSO)378.00€AMG 579
CAS:AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).Formula:C25H23N5O3Purity:99.35%Color and Shape:SolidMolecular weight:441.48Ref: TM-T14217
1mg35.00€2mg47.00€5mg73.00€10mg105.00€25mgTo inquire50mgTo inquire1mL*10mM (DMSO)82.00€Vardenafil hydrochloride trihydrate
CAS:Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.Formula:C23H32N6O4S·HCl·3H2OPurity:99.77%Color and Shape:SolidMolecular weight:579.11Ref: TM-T4097
5mg47.00€10mg70.00€25mg125.00€50mg187.00€100mg298.00€200mg444.00€500mg715.00€1mL*10mM (DMSO)63.00€Enpp-1-IN-1
CAS:Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)Formula:C17H17N3O3SPurity:97.52%Color and Shape:SolidMolecular weight:343.4Ref: TM-T7888
1mg133.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)303.00€N-Ethyl tadalafil
CAS:N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.Formula:C23H21N3O4Purity:99.58%Color and Shape:SolidMolecular weight:403.43BI 1015550
CAS:Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and quality-assured.Formula:C20H25ClN6O2SPurity:100% - 99.71%Color and Shape:SoildMolecular weight:448.97Deltasonamide 2 (TFA)
CAS:Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.Formula:C32H40ClF3N6O6S2Purity:98%Color and Shape:SolidMolecular weight:761.28Carbodenafil
CAS:Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).Formula:C24H32N6O3Purity:98.96%Color and Shape:SolidMolecular weight:452.55Autotaxin-IN-5
CAS:Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.Formula:C30H29N9O2Purity:98%Color and Shape:SolidMolecular weight:547.61Enpp/Carbonic anhydrase-IN-1
CAS:Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase.Formula:C23H25NO4SPurity:100%Color and Shape:SoildMolecular weight:411.51GSK356278
CAS:GSK356278: selective PDE4A/B/D inhibitor, pIC50~8.7, anti-inflammatory, anxiolytic, cognition-enhancing.Formula:C21H25N7O2SPurity:99.43% - 99.79%Color and Shape:SolidMolecular weight:439.53CP671305
CAS:CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.Formula:C23H19FN2O7Purity:99.39%Color and Shape:SolidMolecular weight:454.42,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide
CAS:2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide is a PDE inhibitor.Formula:C9H9Cl2F2NO3SPurity:98.60%Color and Shape:SolidMolecular weight:320.14Ref: TM-T50062
1mg84.00€2mg111.00€5mg172.00€10mg249.00€25mg426.00€50mg627.00€100mg893.00€1mL*10mM (DMSO)172.00€ent-Tadalafil
CAS:ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).Formula:C22H19N3O4Purity:98%Color and Shape:SolidMolecular weight:389.4Ro 20-1724
CAS:Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Formula:C15H22N2O3Purity:98% - 99.14%Color and Shape:SolidMolecular weight:278.35Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formula:C40H37N5OPurity:99.06%Color and Shape:SolidMolecular weight:603.75SEP-0372814
CAS:SEP-0372814 is a potent inhibitor of PDE10.Formula:C21H19N7Purity:99.29%Color and Shape:SolidMolecular weight:369.42BC 11-38
CAS:BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Formula:C15H16N2OS2Purity:97.71% - 98.72%Color and Shape:SolidMolecular weight:304.43Ref: TM-T21865
1mg35.00€5mg70.00€10mg97.00€25mg202.00€50mg329.00€100mg527.00€200mg747.00€1mL*10mM (DMSO)81.00€Zardaverine
CAS:Zardaverine (BY 290) is a PDE3/4 inhibitor with anti-hepatocarcinogenic activity and is used in the study of acute renal failure and chronic airflow obstructionFormula:C12H10F2N2O3Purity:99.11%Color and Shape:SolidMolecular weight:268.22WAY-313170
CAS:WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.Formula:C19H17ClN2O2S2Purity:99.3%Color and Shape:SolidMolecular weight:404.93RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFormula:C19H14ClN5O4Purity:99.25%Color and Shape:SolidMolecular weight:411.8Ref: TM-T23256
2mg34.00€5mg52.00€10mg85.00€25mg170.00€50mg259.00€100mg374.00€200mg545.00€1mL*10mM (DMSO)65.00€ITI-214
CAS:ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits potent PDE1 inhibitory activity.Formula:C29H29FN7O5PPurity:98.21%Color and Shape:SolidMolecular weight:605.56Ref: TM-T11689
1mg74.00€2mg97.00€5mg166.00€10mg303.00€25mg533.00€50mg750.00€100mg1,064.00€1mL*10mM (DMSO)217.00€PF-05180999
CAS:α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.Formula:C19H17F3N8Purity:99.43%Color and Shape:SolidMolecular weight:414.39Ziritaxestat
CAS:Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.Formula:C30H33FN8O2SPurity:97% - 99.85%Color and Shape:SolidMolecular weight:588.7UK 227786
CAS:UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.Formula:C22H22Cl2N4O4Purity:100%Color and Shape:SoildMolecular weight:477.34Ref: TM-T11220L
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)304.00€Arofylline
CAS:Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.Formula:C14H13ClN4O2Purity:97.98%Color and Shape:SolidMolecular weight:304.73Verofylline
CAS:Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for theFormula:C12H18N4O2Purity:97.97% - 99.55%Color and Shape:SolidMolecular weight:250.3Siguazodan
CAS:Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.Formula:C14H16N6OPurity:99.63% - 99.77%Color and Shape:SolidMolecular weight:284.32Ref: TM-T12913
1mg42.00€5mg88.00€10mg127.00€25mg264.00€50mg424.00€100mg655.00€200mg924.00€1mL*10mM (DMSO)87.00€GSK256066 Trifluoroacetate
CAS:GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.Formula:C29H27F3N4O7SColor and Shape:SolidMolecular weight:632.61THPP-1
CAS:THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).Formula:C23H21ClN6O3Purity:99.46%Color and Shape:SolidMolecular weight:464.9CI-1044
CAS:CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).Formula:C23H19N5O2Color and Shape:SolidMolecular weight:397.43Anti-ALDH7A1 Antibody-FITC (5P692)
Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.Color and Shape:Odour LiquidML-030
CAS:ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.Formula:C20H20N4O4SPurity:97.93%Color and Shape:SolidMolecular weight:412.46Nortadalafil
CAS:Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.Formula:C21H17N3O4Purity:99.42%Color and Shape:SolidMolecular weight:375.38Ref: TM-T6147
1mg37.00€2mg52.00€5mg79.00€10mg111.00€25mg202.00€50mg354.00€100mg567.00€200mg805.00€500mg1,198.00€1mL*10mM (DMSO)87.00€Olprinone
CAS:Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuateFormula:C14H10N4OPurity:99.68%Color and Shape:SolidMolecular weight:250.26Dovramilast
CAS:Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.Formula:C24H28N2O6SPurity:98.75% - 99.74%Color and Shape:SolidMolecular weight:472.55Anagrelide
CAS:Anagrelide (Xagrid) is a Platelet-reducing Agent.Formula:C10H7Cl2N3OPurity:100%Color and Shape:SolidMolecular weight:256.09Balipodect
CAS:Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.Formula:C23H17FN6O2Purity:98.32% - 98.97%Color and Shape:SolidMolecular weight:428.42Ref: TM-T1745
1mg38.00€2mg49.00€5mg79.00€10mg93.00€25mg156.00€50mg256.00€100mg444.00€1mL*10mM (DMSO)79.00€TPN171
CAS:TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonaryFormula:C24H35N5O3Purity:100%Color and Shape:SolidMolecular weight:441.57PQ-10
CAS:PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.Formula:C22H21N5O3Purity:99.30%Color and Shape:SolidMolecular weight:403.43Ref: TM-T24656
2mg34.00€5mg52.00€10mg85.00€25mg170.00€50mg259.00€100mg374.00€200mg545.00€1mL*10mM (DMSO)57.00€Mirodenafil dihydrochloride
CAS:Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H39Cl2N5O5SPurity:99.64% - 99.78%Color and Shape:SolidMolecular weight:604.59Bay 60-7550
CAS:Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.Formula:C27H32N4O4Purity:98.14%Color and Shape:SolidMolecular weight:476.57ENPP1 Inhibitor C
CAS:ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.Formula:C15H18N6Color and Shape:SolidMolecular weight:282.34Vardenafil dihydrochloride
CAS:Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.Formula:C23H34Cl2N6O4SPurity:98%Color and Shape:SolidMolecular weight:561.52Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formula:C12H12N2O2SPurity:95.52%Color and Shape:SolidMolecular weight:248.3KD-027
CAS:KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.Formula:C25H35N7O6SPurity:99.55%Color and Shape:SolidMolecular weight:561.65MY-5445
CAS:MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).Formula:C20H14ClN3Purity:99.77%Color and Shape:SolidMolecular weight:331.8BW-A 78U
CAS:BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.Formula:C13H12FN5Purity:99.45%Color and Shape:SolidMolecular weight:257.27Ref: TM-T5101
1mg39.00€5mg101.00€10mg153.00€25mg249.00€50mg359.00€100mg507.00€200mg695.00€1mL*10mM (DMSO)44.00€Piclamilast
CAS:Piclamilast (RP 73401) is a PDE4 inhibitor.Formula:C18H18Cl2N2O3Purity:98.28%Color and Shape:SolidMolecular weight:381.25Filaminast
CAS:Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.Formula:C15H20N2O4Purity:98.44% - 99.64%Color and Shape:SolidMolecular weight:292.33Ref: TM-T31792
1mg226.00€5mg552.00€10mg735.00€25mg1,111.00€50mg1,491.00€100mg2,005.00€200mg2,707.00€1mL*10mM (DMSO)500.00€Senazodan hydrochloride
CAS:Senazodan hydrochloride (Senazodan HCl) is a Ca2+ sensitizer and phosphodiesterase 3 (PDE3) inhibitor used in the study of cardiovascular diseases.Formula:C15H15ClN4OPurity:99.93%Color and Shape:SolidMolecular weight:302.76Ensifentrine
CAS:Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), thatFormula:C26H31N5O4Purity:98.45% - 99.94%Color and Shape:SolidMolecular weight:477.56Ref: TM-T25376
1mg35.00€5mg96.00€10mg160.00€25mg329.00€50mg533.00€100mg847.00€200mg1,159.00€1mL*10mM (DMSO)105.00€Lodenafil
CAS:Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)Formula:C23H32N6O5SPurity:99.92%Color and Shape:SolidMolecular weight:504.6Ref: TM-T7346
2mg35.00€5mg50.00€10mg81.00€25mg129.00€50mg187.00€100mg259.00€200mg373.00€1mL*10mM (DMSO)56.00€BAY 2666605
CAS:BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.Formula:C17H12F4N2O2Purity:99.98%Color and Shape:SolidMolecular weight:352.28Ref: TM-T9805
1mg97.00€5mg235.00€10mg376.00€25mg828.00€50mg1,320.00€100mg2,118.00€1mL*10mM (DMSO)259.00€
![[11C]MP 10](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT6042.webp&w=3840&q=75)
