Aminopeptidase
Aminopeptidases are a group of enzymes that catalyze the cleavage of amino acids from the N-terminus of peptides and proteins, playing a crucial role in protein maturation and degradation. These enzymes are involved in various physiological processes, including antigen processing, peptide hormone regulation, and cellular homeostasis. Inhibitors of aminopeptidases are of interest in the treatment of diseases such as cancer, inflammation, and infectious diseases. At CymitQuimica, we provide a variety of aminopeptidase inhibitors to support your research in proteomics, drug development, and disease treatment.
Products of "Aminopeptidase"
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ERAP1-IN-1
CAS:ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.Formula:C20H21F3N2O5SPurity:98.60%Color and Shape:SolidMolecular weight:458.45Ref: TM-T11221
1mg87.00€5mg170.00€10mg273.00€25mg449.00€50mg615.00€100mg843.00€200mg1,130.00€1mL*10mM (DMSO)170.00€ARM1
CAS:ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase.Formula:C16H14N2SPurity:99.28%Color and Shape:SolidMolecular weight:266.36Ref: TM-T21859
5mg50.00€10mg80.00€25mg145.00€50mg210.00€100mg309.00€200mg444.00€1mL*10mM (DMSO)52.00€QGC583
CAS:QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.Formula:C13H20NO5PColor and Shape:SolidMolecular weight:301.28SC-57461A
CAS:SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor.Formula:C20H26ClNO3Purity:99.91%Color and Shape:SolidMolecular weight:363.9Aminopeptidase-IN-1
CAS:Aminopeptidase-IN-1: potent IRAP blocker, Ki 7.7 μM, useful for cognitive/memory disorder research.Formula:C18H16N2O6Purity:98.37%Color and Shape:SolidMolecular weight:356.33SC-22716
CAS:SC-22716 is a LTA4 hydrolase inhibitor.SC-22716 has anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.Formula:C18H21NOPurity:99.91%Color and Shape:SolidMolecular weight:267.37Tosedostat
CAS:Tosedostat (CHR-2797), an oral M1 aminopeptidase inhibitor, turns into CHR-79888, blocks tumor cell proteins, causing cell death.Formula:C21H30N2O6Purity:98.14% - 99.4%Color and Shape:SolidMolecular weight:406.47SDUY817
SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24Acebilustat
CAS:Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.Formula:C29H27N3O4Purity:99.47% - 99.59%Color and Shape:SolidMolecular weight:481.54Ref: TM-T3715
2mg38.00€5mg58.00€10mg80.00€25mg145.00€50mg225.00€100mg334.00€200mg467.00€1mL*10mM (DMSO)65.00€L(+)-Leucinol
CAS:L(+)-Leucinol is a potent inhibitor of leucine aminopeptidase.Formula:C6H15NOPurity:98%Color and Shape:Clear Colorless To Slightly Yellow LiquidMolecular weight:117.19DG051
CAS:DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM).Formula:C21H25Cl2NO4Purity:98.26%Color and Shape:SolidMolecular weight:426.33Ref: TM-TQ0047
1mg37.00€5mg111.00€10mg187.00€25mg399.00€50mg635.00€100mg1,017.00€200mg1,359.00€1mL*10mM (DMSO)124.00€Puromycin aminonucleoside
CAS:Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.Formula:C12H18N6O3Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:294.31Apstatin TFA
Apstatin TFA is a potent inhibitor of aminopeptidase P (APP), with Ki values of 2.6 µM for rat APP and 0.64 µM for human APP. This compound also exhibits cardioprotective properties.Formula:C25H34F3N5O7Color and Shape:SolidMolecular weight:573.56Methyl arachidate
CAS:Methyl arachidate (Methyl Icosanoate) is an esterified form of arachidic acidFormula:C21H42O2Purity:≥95%Color and Shape:White PowderMolecular weight:326.56LYS006 hydrochloride
CAS:LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 value of 2 nM. It is applicable in the study of inflammatory and autoimmune diseases. For further details, please refer to compound 29 in patent document WO2015092740A1.Formula:C16H15Cl2FN6O3Color and Shape:SolidMolecular weight:429.23Firibastat
CAS:Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33.Formula:C8H20N2O6S4Purity:99.88%Color and Shape:SolidMolecular weight:368.51Bestatin hydrochloride
CAS:Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.Formula:C16H25ClN2O4Purity:100% - 98%Color and Shape:SolidMolecular weight:344.84Ref: TM-T3529
5mg51.00€10mg74.00€25mg106.00€50mg168.00€100mg279.00€200mg426.00€500mg692.00€1mL*10mM (DMSO)57.00€ERAP1 modulator-1
CAS:ERAP1 modulator-1 (Compound 1) is a regulator of endoplasmic reticulum aminopeptidase 1 (ERAP1) with an IC50 of less than 250 nM.Formula:C23H23F3N2O5SColor and Shape:SolidMolecular weight:496.5Actinonin
CAS:Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. It also induces apoptosis and inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase, as well as MMP-1, MMP-3, MMP-8, MMP-9, and meprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin exhibits antiproliferative and antitumor activities [1][2][3][4][5].Formula:C19H35N3O5Color and Shape:SolidMolecular weight:385.5SDUY816
SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24
