Retinoid Receptor
Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.
Products of "Retinoid Receptor"
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Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Formula:C24H28O2Purity:99% - 99.65%Color and Shape:White SolidMolecular weight:348.48Tarenflurbil
CAS:Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.Formula:C15H13FO2Purity:100% - 98%Color and Shape:SolidMolecular weight:244.26LY 178002
CAS:LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.Formula:C18H25NO2SPurity:98%Color and Shape:SolidMolecular weight:319.46LG100268
CAS:LG100268 is a selective, and oral RXR agonist,inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.Formula:C24H29NO2Purity:99.83%Color and Shape:SolidMolecular weight:363.49LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formula:C23H26O3Purity:98.65%Color and Shape:SolidMolecular weight:350.45Ref: TM-T11844
2mg47.00€5mg70.00€10mg97.00€25mg167.00€50mg249.00€100mg369.00€200mg545.00€1mL*10mM (DMSO)77.00€CD2665
CAS:CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.Formula:C31H34O5Purity:99.67%Color and Shape:SolidMolecular weight:486.6trifarotene
CAS:Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.Formula:C29H33NO4Purity:99.78%Color and Shape:SolidMolecular weight:459.58AC-55649
CAS:AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.Formula:C21H26O2Purity:99.84%Color and Shape:SolidMolecular weight:310.43ER 50891
CAS:ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.Formula:C29H24N2O2Purity:99.49%Color and Shape:SolidMolecular weight:432.51HX 531
CAS:HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.Formula:C29H29N3O4Purity:98.59% - 99.43%Color and Shape:SolidMolecular weight:483.56MM 11253
CAS:MM 11253 is a RARγ antagonist with IC50 of 44nM.Formula:C28H30O2S2Purity:98.62%Color and Shape:SolidMolecular weight:462.67BMS 753
CAS:BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).Formula:C21H21NO4Purity:98.4%Color and Shape:SolidMolecular weight:351.4Fluorobexarotene
CAS:Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.Formula:C24H27FO2Purity:99.23%Color and Shape:SolidMolecular weight:366.47Ref: TM-T11303
1mg173.00€5mg439.00€10mg648.00€25mg1,017.00€50mg1,378.00€100mg1,853.00€500mg3,695.00€1mL*10mM (DMSO)354.00€Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Ref: TM-T6696
5mg38.00€10mg49.00€25mg88.00€50mg147.00€100mg256.00€200mg334.00€500mg563.00€1mL*10mM (DMSO)55.00€AGN 196996
CAS:AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).Formula:C24H20BrNO5Purity:≥98%Color and Shape:SolidMolecular weight:482.32Ref: TM-T10261
1mg59.00€5mg131.00€10mg190.00€25mg329.00€50mg477.00€100mg702.00€1mL*10mM (DMSO)138.00€Ch55
CAS:Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.Formula:C24H28O3Purity:99.01%Color and Shape:SolidMolecular weight:364.48Ref: TM-T14946
1mg43.00€5mg90.00€10mg130.00€25mg264.00€50mg414.00€100mg645.00€200mg895.00€1mL*10mM (DMSO)88.00€Isotretinoin
CAS:Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promoteFormula:C20H28O2Purity:98.06% - 99.61%Color and Shape:Reddish-Orange Plates From Isopropyl Alcohol (Ntp 1992)Molecular weight:300.44BMS453
CAS:BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.Formula:C27H24O2Purity:99.78%Color and Shape:SolidMolecular weight:380.48UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purity:99.82%Color and Shape:SolidMolecular weight:436.58Ref: TM-T17209
1mg35.00€2mg52.00€5mg74.00€10mg119.00€25mg243.00€50mg406.00€100mg607.00€1mL*10mM (DMSO)86.00€K-8012
CAS:K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formula:C23H23FN4Purity:98.24%Color and Shape:SolidMolecular weight:374.45Ref: TM-T24240
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)266.00€
