P450
Cytochrome P450 enzymes are a large family of enzymes involved in the metabolism of various endogenous and exogenous compounds, including drugs, toxins, and hormones. P450 inhibitors are widely used to study drug metabolism, pharmacokinetics, and the role of these enzymes in disease states such as cancer and liver disorders. At CymitQuimica, we provide a broad selection of P450 inhibitors to support your research in pharmacology, toxicology, and metabolic regulation.
Products of "P450"
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BI 653048 phosphate
CAS:BI 653048 phosphate is a selective and orally active agonist of nonsteroidal glucocorticoid (GC)(IC50 : 55 nM).Formula:C23H28F4N3O8PSPurity:98%Color and Shape:SolidMolecular weight:613.52Canadine
CAS:Canadine has antioxidant activity with low-toxic effect.Formula:C20H21NO4Purity:98%Color and Shape:SolidMolecular weight:339.39Licopyranocoumarin
CAS:Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrialFormula:C21H20O7Purity:98%Color and Shape:SolidMolecular weight:384.38BMS-819881
CAS:BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM and it also is selective and potent forFormula:C24H21ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:468.95Uniconazole
CAS:Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM).Formula:C15H18ClN3OPurity:99.94%Color and Shape:White-Light Brown CrystallineMolecular weight:291.78BI 653048
CAS:BI 653048 is a selective and orally active agonist of nonsteroidal glucocorticoid (IC50: 55 nM). BI 653048 is also an HCV NS3 protease inhibitor.Formula:C23H25F4N3O4SPurity:98%Color and Shape:SolidMolecular weight:515.52Casopitant mesylate
CAS:Casopitant mesylate (GW679769B): Selective, brain-permeable NK1 receptor blocker, oral antiemetic.Formula:C31H39F7N4O5SPurity:98%Color and Shape:SolidMolecular weight:712.721-Ethynylpyrene
CAS:1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).Formula:C18H10Purity:98.89%Color and Shape:SolidMolecular weight:226.272,3',4,6-Tetrahydroxybenzophenone
CAS:2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity.Formula:C13H10O5Color and Shape:SolidMolecular weight:246.22Humantenirine
CAS:Humantenirine is a natural product of Gelsemium, Loganiaceae.Formula:C21H26N2O4Purity:98%Color and Shape:SolidMolecular weight:370.44CRTH2-IN-1
CAS:CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.Formula:C21H21FN2O4SPurity:98%Color and Shape:SolidMolecular weight:416.47(S)-Mephenytoin
CAS:(S)-Mephenytoin: (+)-enantiomer, anticonvulsant, CYP2C19 substrate for analyzing CYP450 metabolism.Formula:C12H14N2O2Purity:99.05% - 99.82%Color and Shape:SolidMolecular weight:218.25Ref: TM-T21529
1mg56.00€5mg119.00€10mg187.00€25mg376.00€50mg562.00€100mg802.00€1mL*10mM (DMSO)131.00€Norfluoxetine Hydrochloride
CAS:Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.Formula:C16H17ClF3NOPurity:99.75%Color and Shape:SolidMolecular weight:331.76Ref: TM-T21029
1mg48.00€5mg135.00€10mg205.00€25mg369.00€50mg502.00€100mg727.00€200mg1,017.00€1mL*10mM (DMSO)99.00€GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formula:C24H16Cl2F2N6OPurity:98.59%Color and Shape:SolidMolecular weight:513.33Ref: TM-T4488
1mg47.00€2mg59.00€5mg92.00€10mg117.00€25mg172.00€50mg271.00€100mg454.00€1mL*10mM (DMSO)95.00€Climbazole
CAS:Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.Formula:C15H17ClN2O2Purity:98.23%Color and Shape:White Solid CrystallineMolecular weight:292.76Methysticin
CAS:Methysticin, a major kavalactone extracted from kava, can induce CYP1A1.Formula:C15H14O5Purity:98%Color and Shape:SolidMolecular weight:274.27Cephaeline dihydrochloride
CAS:(-)-Cephaeline (dihydrochloride) is an enantiomer of Cephaeline. Cephaeline is a selective CYP2D6 inhibitor (IC50: 121 μM).Formula:C28H40Cl2N2O4Color and Shape:SolidMolecular weight:539.546',7'-Dihydroxybergamottin
CAS:6',7'-Dihydroxybergamottin (DHB) inhibits CYP3A4 and POR; affects nifedipine oxidation.Formula:C21H24O6Purity:98%Color and Shape:SolidMolecular weight:372.41Dipterocarpol
CAS:Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng.Formula:C30H50O2Purity:98%Color and Shape:SolidMolecular weight:442.7282-Hydroxy-1-Methoxyaporphine
CAS:2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.Formula:C18H19NO2Purity:98%Color and Shape:SolidMolecular weight:281.355
