HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
Products of "HMG-CoA Reductase"
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Found 15 products on this category.
Anhydrosimvastatin
CAS:Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.Formula:C25H36O4Purity:99.63%Color and Shape:SolidMolecular weight:400.55Ref: TM-T10324
1mg137.00€5mg298.00€10mg430.00€25mg652.00€50mg900.00€100mg1,206.00€1mL*10mM (DMSO)328.00€Apomine
CAS:Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂,可在体外促进骨髓瘤细胞的凋亡,并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。Formula:C28H52O7P2Purity:100%Color and Shape:SolidMolecular weight:562.66Ref: TM-T26644
1mg120.00€5mg264.00€10mg376.00€25mg630.00€50mg880.00€100mg1,169.00€1mL*10mM (DMSO)325.00€Monacolin J
CAS:Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formula:C19H28O4Purity:98.06%Color and Shape:SolidMolecular weight:320.42Ref: TM-T12092
1mg79.00€5mg160.00€10mg235.00€25mg398.00€50mg567.00€100mg820.00€1mL*10mM (DMSO)170.00€Atorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formula:C33H35FN2O5Purity:99.37% - 99.69%Color and Shape:SolidMolecular weight:558.642'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.Formula:C23H34O5Purity:98%Color and Shape:SolidMolecular weight:390.51Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purity:99.84%Color and Shape:White Crystalline PowderMolecular weight:468.58Fluvastatin
CAS:Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.Formula:C24H26FNO4Purity:98.94%Color and Shape:SolidMolecular weight:411.47Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Formula:C33H33FN2O4Purity:98.16%Color and Shape:SolidMolecular weight:540.62HMG499
CAS:HMG499 inhibits HMG-CoA reductase (IC50: 0.41μM), reduces statin-induced HMGCR, lowers cholesterol, and lessens atherosclerosis.Formula:C33H54O3Purity:98%Color and Shape:SolidMolecular weight:498.78SR12813
CAS:SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formula:C24H42O7P2Purity:99.43%Color and Shape:SolidMolecular weight:504.53Tert-Buthyl Pitavastatin
CAS:Tert-Buthyl Pitavastatin is a metabolite of Pitavastatin, a potent HMG-CoA reductase inhibitor.Formula:C29H32FNO4Purity:99.57%Color and Shape:SolidMolecular weight:477.57Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFormula:C24H31FO3Purity:98.08%Color and Shape:SolidMolecular weight:386.57-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purity:97.59% - 99.46%Color and Shape:SolidMolecular weight:400.65Pitavastatin lactone
CAS:Pitavastatin lactone, a major human metabolite, potently inhibits HMG-CoA reductase with minimal hepatic microsome metabolism.Formula:C25H22FNO3Purity:98.20%Color and Shape:White To Off-White PowderMolecular weight:403.45Ref: TM-T12490
5mg47.00€10mg65.00€25mg126.00€50mg188.00€100mg283.00€200mg424.00€1mL*10mM (DMSO)64.00€Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Formula:C14H23NO3Purity:98.28% - 98.47%Color and Shape:SolidMolecular weight:253.34
