Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Products of "Lipoxygenase"
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ALOX15-IN-2
CAS:ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Formula:C23H29N3O4SPurity:99.32%Color and Shape:SolidMolecular weight:443.56Ref: TM-T62606
1mg48.00€5mg96.00€10mg169.00€25mg329.00€50mg567.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)105.00€h15-LOX-2 inhibitor 3
CAS:Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.Formula:C22H13N5O3Color and Shape:SolidMolecular weight:395.37PD-146176
CAS:Controlled ProductApplications PD-146176 is a potent and selective 15-LO inhibitor.Formula:C15H11NSColor and Shape:NeatMolecular weight:237.32COX-2/15-LOX-IN-3
COX-2/15-LOX-IN-3 (compound 5k) serves as a dual inhibitor for COX-2 and 15-LOX, demonstrating inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM,Formula:C25H24FN3O3SPurity:98%Color and Shape:SolidMolecular weight:465.5411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg60.00€5mg137.00€10mg210.00€25mg356.00€50mg525.00€100mg750.00€1mL*10mM (DMSO)140.00€Utreloxastat
CAS:Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis .Formula:C18H28O2Purity:99.95%Color and Shape:SolidMolecular weight:276.41Ref: TM-T60507
1mg92.00€5mg216.00€10mg311.00€25mg533.00€50mg787.00€100mg1,378.00€200mg1,853.00€1mL*10mM (DMSO)235.00€Lipoxygenase
CAS:Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Color and Shape:Solid4-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24Shogaol
CAS:6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.Formula:C17H24O3Purity:98.26% - 99.39%Color and Shape:SolidMolecular weight:276.37Ref: TM-T6S1699
2mg43.00€5mg62.00€10mg92.00€25mg180.00€50mg283.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)67.00€Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.49%Color and Shape:Yellowish SolidMolecular weight:379.88Ref: TM-T6568
5mg47.00€10mg70.00€25mg126.00€50mg187.00€100mg279.00€200mg415.00€500mg658.00€1mL*10mM (DMSO)50.00€Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purity:99.78%Color and Shape:SolidMolecular weight:301.72Ref: TM-T19679
1mg202.00€5mg472.00€10mg707.00€25mg1,035.00€50mg1,311.00€100mg1,663.00€1mL*10mM (DMSO)469.00€5-LOX-IN-1
CAS:5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.Formula:C20H18N2O2SPurity:97.45%Color and Shape:SolidMolecular weight:350.433-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formula:C32H50O5Purity:98.24%Color and Shape:SolidMolecular weight:514.74SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurity:98% - 99.68%Color and Shape:SolidMolecular weight:297.35CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46Ref: TM-T8950
1mg48.00€2mg63.00€5mg93.00€10mg139.00€25mg274.00€50mg425.00€100mg625.00€500mg1,311.00€1mL*10mM (DMSO)97.00€Bunaprolast
CAS:Bunaprolast (U66858) is a novel and potent leukotriene B4 (LTB4) inhibitor.Bunaprolast exhibits oxidative degradation activity and inhibits lipoxygenase andFormula:C17H20O3Purity:99.9%Color and Shape:SolidMolecular weight:272.34LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formula:C21H25FN4O2SColor and Shape:SolidMolecular weight:416.51CCT365623 hydrochloride
CAS:CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.Formula:C18H18ClNO4S3Purity:98%Color and Shape:SolidMolecular weight:443.99
