PKM
Pyruvate Kinase M2 (PKM) is an isoform of pyruvate kinase that plays a crucial role in glycolysis, converting phosphoenolpyruvate to pyruvate. PKM2 is involved in the regulation of metabolic reprogramming in cancer cells, making it a potential target for cancer therapy. Inhibitors of PKM2 can alter metabolic pathways, reduce tumor growth, and induce cell death in cancer cells. At CymitQuimica, we provide PKM2 inhibitors to support your research in cancer metabolism, oncology, and therapeutic development.
Products of "PKM"
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Found 10 products on this category.
DASA-58
CAS:DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Formula:C19H23N3O6S2Purity:96.96% - 99.28%Color and Shape:SolidMolecular weight:453.53PKM2-IN-1
CAS:PKM2-IN-1 (compound 3k) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.Formula:C18H19NO2S2Purity:99.49% - 99.68%Color and Shape:SolidMolecular weight:345.48Ref: TM-T4170
1mg40.00€2mg51.00€5mg85.00€10mg115.00€25mg205.00€50mg354.00€100mg567.00€200mg810.00€500mg1,216.00€PKM2 activator 2
CAS:PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuatesFormula:C20H18F2N2O4S2Purity:100%Color and Shape:SolidMolecular weight:452.49Mitapivat sulfate hydrate
CAS:Mitapivat sulfate hydrate (AG 348 sulfate hydrate) is a pyruvate kinase (PK) allosteric activator, used to study pyruvate kinase deficiency.Formula:C24H26N4O3S1H2SO43H2OPurity:99.40%Color and Shape:SolidMolecular weight:526.6Mitapivat
CAS:Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.Formula:C24H26N4O3SPurity:99.47% - 99.83%Color and Shape:SolidMolecular weight:450.55TEPP-46
CAS:TEPP-46 (ML265) is an activator of pyruvate kinase M2 (PKM2), selective for PKM1, PKL and PKR. TEPP-46 has antitumor activity. Cost-effective and quality-assured.Formula:C17H16N4O2S2Purity:98.21% - 98.77%Color and Shape:SolidMolecular weight:372.46Ref: TM-T7214
1mg48.00€5mg96.00€10mg144.00€25mg235.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)96.00€PKM2 activator 5
CAS:PKM2 activator 5 is a novel and potent PKM2 activator (AC50: 0.316 µM) with potential anticancer activity for the study of cancer metabolism-related diseases.Formula:C18H19FN2O6S2Purity:98%Color and Shape:SolidMolecular weight:442.48Dimethylaminomicheliolide HCl
CAS:Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvateFormula:C17H28ClNO3Purity:99.55%Color and Shape:SoildMolecular weight:329.86PKR-IN-2
CAS:PKR-IN-2 is a activator of pyruvate kinase (PKR).Formula:C24H28N4O4SPurity:99.14%Color and Shape:SolidMolecular weight:468.57Ref: TM-T12499
1mg81.00€5mg145.00€10mg207.00€25mg334.00€50mg467.00€100mg655.00€200mg883.00€1mL*10mM (DMSO)149.00€PKM2 inhibitor G
CAS:PKM2 inhibitor G is a inhibitor of pyruvate kinase.Formula:C16H15NO3SPurity:99.54%Color and Shape:SoildMolecular weight:301.36Ref: TM-T67900
1mg185.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)404.00€
