5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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Pizotifen Malate
CAS:Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.Formula:C19H21NS·C4H6O5Purity:100%Color and Shape:SolidMolecular weight:429.53Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formula:C21H24N2O4SPurity:99%Color and Shape:SolidMolecular weight:400.49Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purity:96.74%Color and Shape:SolidMolecular weight:244.2(Rac)-Norcisapride
CAS:Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Formula:C14H20ClN3O3Purity:99.13%Color and Shape:SoildMolecular weight:313.78(S)-Amisulpride
CAS:(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.Formula:C17H27N3O4SPurity:98.38%Color and Shape:SolidMolecular weight:369.48Ref: TM-T26375
1mg50.00€2mg71.00€5mg114.00€10mg178.00€25mg340.00€50mg538.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)126.00€AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formula:C14H21BrN2OColor and Shape:SolidMolecular weight:313.23Ondansetron hydrochloride dihydrate
CAS:Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.Formula:C18H19N3O·HCl·2H2OPurity:99.92%Color and Shape:White Crystal PowderMolecular weight:365.86SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:464.87Ipsapirone
CAS:Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.Formula:C19H23N5O3SPurity:99.01%Color and Shape:SolidMolecular weight:401.485-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formula:C9H14N4Color and Shape:SolidMolecular weight:178.234SB-200646A
CAS:SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Formula:C15H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:302.76Adatanserin
CAS:Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist.Formula:C21H31N5OPurity:99.17%Color and Shape:SolidMolecular weight:369.5ST1936
CAS:ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.Formula:C13H17ClN2Purity:98.00%Color and Shape:SolidMolecular weight:236.74Ref: TM-T23396
1mg47.00€5mg117.00€10mg188.00€25mg334.00€50mg497.00€100mg720.00€200mg1,008.00€1mL*10mM (DMSO)130.00€Cyproheptadine hydrochloride
CAS:Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Formula:C21H21N·HClPurity:99.88% - 99.97%Color and Shape:SolidMolecular weight:323.86Tropanserin
CAS:Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Formula:C17H23NO2Purity:99.74%Color and Shape:SolidMolecular weight:273.37Sarizotan 2HCl
CAS:Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.Formula:C22H23Cl2FN2OPurity:98.83%Color and Shape:SoildMolecular weight:421.345-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Formula:C19H22FNO2Purity:98%Color and Shape:SolidMolecular weight:315.38Sulamserod hydrochloride
CAS:Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formula:C19H29Cl2N3O5SColor and Shape:SolidMolecular weight:482.42LY 344864
CAS:LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Formula:C23H24O6Purity:98.55% - 99.08%Color and Shape:SolidMolecular weight:396.43WAY 163909
CAS:WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).Formula:C14H18N2Purity:98%Color and Shape:SolidMolecular weight:214.315-HT7 agonist 1
CAS:5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).Formula:C19H20ClN3Purity:98.61%Color and Shape:SolidMolecular weight:325.84Ref: TM-T10170
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)255.00€YM-31636 free base
CAS:YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.Formula:C14H11N3SColor and Shape:SolidMolecular weight:253.325-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Formula:C19H22N2O2Purity:98%Color and Shape:SolidMolecular weight:310.39Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purity:99.55% - 99.55%Color and Shape:White To Off-White SolidMolecular weight:407.0425N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Color and Shape:SolidMolecular weight:382.84Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Formula:C18H19FN2O3SPurity:97.50% - 99.33%Color and Shape:SolidMolecular weight:362.42Venlafaxine hydrochloride
CAS:Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.Formula:C17H28ClNO2Purity:99.86%Color and Shape:White Crystalline PowderMolecular weight:313.863Adatanserin hydrochloride
CAS:Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formula:C21H32ClN5OPurity:99.64%Color and Shape:SolidMolecular weight:405.96Olopatadine hydrochloride
CAS:Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Formula:C21H23NO3·HClPurity:99.62% - 99.64%Color and Shape:White SolidMolecular weight:373.87Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37SR 57227 hydrochloride
CAS:SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Formula:C10H14ClN3·HClPurity:99.89%Color and Shape:SolidMolecular weight:248.15Ref: TM-T23394
5mg50.00€10mg74.00€25mg126.00€50mg210.00€100mg313.00€200mg445.00€1mL*10mM (DMSO)49.00€RS 56812 hydrochloride
CAS:5-HT3 partial agonistFormula:C18H22ClN3O2Purity:97.69%Color and Shape:SolidMolecular weight:347.84N-Desmethyl Pimavanserin
CAS:N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formula:C24H32FN3O2Purity:98.02%Color and Shape:SolidMolecular weight:413.53Urapidil
CAS:Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.Formula:C20H29N5O3Purity:100% - 99.85%Color and Shape:SolidMolecular weight:387.48Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.77%Color and Shape:SolidMolecular weight:359.47Pizotifen
CAS:Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.Formula:C19H21NSPurity:99.93%Color and Shape:SolidMolecular weight:295.44Ondansetron
CAS:Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.Formula:C18H19N3OPurity:99.92%Color and Shape:White To Yellow CrystalsMolecular weight:293.364-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Olanzapine
CAS:Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formula:C17H20N4SPurity:100% - ≥95%Color and Shape:Yellowish Crystalline PowderMolecular weight:312.43Desvenlafaxine succinate hydrate
CAS:Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).Formula:C20H33NO7Purity:99.26%Color and Shape:White Crystalline PowdeMolecular weight:399.48Dolasetron Mesylate hydrate
CAS:Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Formula:C20H26N2O7SPurity:99.86% - 99.9%Color and Shape:SolidMolecular weight:438.49cis-(Z)-Flupentixol dihydrochloride
CAS:cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Formula:C23H27Cl2F3N2OSPurity:98.07%Color and Shape:SolidMolecular weight:507.44Ebalzotan
CAS:NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.Formula:C19H30N2O2Purity:99.08% - 99.41%Color and Shape:SolidMolecular weight:318.45Relenopride
CAS:YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.Formula:C24H30ClFN4O4Purity:98.91% - 99.20%Color and Shape:SoildMolecular weight:492.97MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Formula:C19H29Cl2N3O3Purity:100.00%Color and Shape:SolidMolecular weight:418.36Ref: TM-T23007
1mg86.00€5mg157.00€10mg215.00€25mg472.00€50mg687.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)281.00€AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormula:C10H13N3OPurity:99.77%Color and Shape:SolidMolecular weight:191.23Naluzotan hydrochloride
CAS:Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 nM, Ki: ~5.1 nM), is used in anxiety and depression studies.Formula:C23H39ClN4O3SPurity:98.61%Color and Shape:SolidMolecular weight:487.1PNU 22394 hydrochloride
CAS:PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonistFormula:C13H17ClN2Purity:97.83%Color and Shape:SolidMolecular weight:236.74RS-67333
CAS:RS-67333 is a partial agonist of 5-HT4R with neuroprotective effects.Formula:C19H29ClN2O2Purity:99.24%Color and Shape:SolidMolecular weight:352.9
