5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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(E)-3,4,5-Trimethoxycinnamic acid
CAS:(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.Formula:C12H14O5Purity:99.83%Color and Shape:SolidMolecular weight:238.24Clovoxamine
CAS:Clovoxamine fumarate (DU 23811 fumarate) is a 5-HT reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activity.Formula:C14H21ClN2O2Purity:98.88% - 99.16%Color and Shape:SolidMolecular weight:284.78Mosapride
CAS:Mosapride (AS-4370) is a selective 5HT4 agonistFormula:C21H25ClFN3O3Purity:99.56%Color and Shape:White To Off-White Crystalline SolidMolecular weight:421.89SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Formula:C28H31ClN4O4Purity:98.40% - 99.23%Color and Shape:SolidMolecular weight:523.02Lafutidine
CAS:Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.Formula:C22H29N3O4SPurity:99.94%Color and Shape:Yellowish White Crystalline PowderMolecular weight:431.55Vilazodone
CAS:Vilazodone (SB659746A): an SSRI and 5-HT-1A agonist, boosts serotonin to treat depression and anxiety.Formula:C26H27N5O2Purity:99.61%Color and Shape:Light Yellow SolidMolecular weight:441.52Agomelatine (L(+)-Tartaric acid)
CAS:Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, andFormula:C19H23NO8Color and Shape:SolidMolecular weight:393.39LP-211
CAS:LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.Formula:C30H34N4OPurity:98.65%Color and Shape:SolidMolecular weight:466.62Ref: TM-T5387
2mg47.00€5mg70.00€10mg96.00€25mg180.00€50mg305.00€100mg487.00€200mg695.00€1mL*10mM (DMSO)77.00€Usmarapride free base
CAS:Usmarapride free base (SUVN-D4010 free base) is a partial agonist of 5-HT4 receptors, used in Alzheimer's disease research.Formula:C21H29N5O2Purity:99.91% - 99.91%Color and Shape:SolidMolecular weight:383.49Glemanserin
CAS:Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.Formula:C20H25NOPurity:99.52%Color and Shape:SolidMolecular weight:295.42Ref: TM-T22964
1mg40.00€5mg88.00€10mg126.00€25mg273.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)88.00€DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99% - 99.89%Color and Shape:SolidMolecular weight:443.37Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Formula:C16H19NOPurity:99.12%Color and Shape:SolidMolecular weight:241.33Ref: TM-T67956
1mg97.00€5mg217.00€10mg325.00€25mg557.00€50mg797.00€100mg1,103.00€500mg2,205.00€1mL*10mM (DMSO)188.00€RG-12915
CAS:RG-12915 is a selective antagonist of 5-HT3(IC50 value of 0.16 nM).Formula:C20H25ClN2O2Purity:98%Color and Shape:SolidMolecular weight:360.88VUF 10166
CAS:VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.Formula:C13H15ClN4Purity:99.66%Color and Shape:SolidMolecular weight:262.74Trazodone hydrochloride
CAS:Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent.Formula:C19H23Cl2N5OPurity:99.50% - 99.52%Color and Shape:SolidMolecular weight:408.335-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFormula:C17H22F2N6OPurity:98%Color and Shape:SolidMolecular weight:364.39Cariprazine
CAS:Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderateFormula:C21H32Cl2N4OPurity:99.68% - 99.87%Color and Shape:SolidMolecular weight:427.41Ref: TM-T4577
1mg51.00€5mg108.00€10mg180.00€25mg316.00€50mg472.00€100mg658.00€200mg938.00€1mL*10mM (DMSO)108.00€Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:99.11% - 99.13%Color and Shape:SolidMolecular weight:233.35Cyamemazine
CAS:Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Formula:C19H21N3SPurity:97.01%Color and Shape:SolidMolecular weight:323.46Ziprasidone hydrochloride
CAS:Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychoticFormula:C21H22CL2N4OSPurity:97.97% - 99.82%Color and Shape:SolidMolecular weight:449.4p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purity:99.78%Color and Shape:SolidMolecular weight:507.43Citalopram
CAS:Citalopram (Lu 10-171), a serotonin and 5-HT reuptake inhibitor.Citalopram has antidepressant activity and may be used to study dementia.Formula:C20H21FN2OPurity:99.89%Color and Shape:SolidMolecular weight:324.39AGH-107
CAS:AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.Formula:C13H12IN3Color and Shape:SolidMolecular weight:337.162-Methyl-5-HT
CAS:2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H14N2OPurity:95.64%Color and Shape:SolidMolecular weight:190.24Ref: TM-T10075
5mg50.00€10mg88.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)52.00€Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.845HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Formula:C20H22BrN3O2SPurity:98.48% - 98.95%Color and Shape:SolidMolecular weight:448.38Remlifanserin
CAS:Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).Formula:C24H29F2N3O2Color and Shape:SolidMolecular weight:429.50S 14506 hydrochloride
CAS:S 14506 hydrochloride is a 5-HT1A receptor full agonist.Formula:C24H27ClFN3O2Purity:99.5%Color and Shape:SolidMolecular weight:443.945-HT3 antagonist 2
CAS:5-HT3 antagonist 2 is an antagonist of 5-HT3 receptor.Formula:C18H21N3OPurity:98%Color and Shape:SolidMolecular weight:295.38Ocaperidone
CAS:Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.Formula:C24H25FN4O2Purity:99.33%Color and Shape:SolidMolecular weight:420.484-hydroxy DiPT hydrochloride
CAS:4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.Formula:C16H25ClN2OColor and Shape:SolidMolecular weight:296.84Renzapride
CAS:Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist used in the study of irritable bowel syndrome.Formula:C16H22ClN3O2Purity:98.97% - 99.09%Color and Shape:SolidMolecular weight:323.82GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Formula:C25H28N4O2Purity:99.76%Color and Shape:SolidMolecular weight:416.52Ref: TM-T8737
1mg43.00€2mg56.00€5mg88.00€10mg119.00€25mg235.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)87.00€Pardoprunox hydrochloride
CAS:Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1)Formula:C12H16ClN3O2Purity:98.73% - 99.13%Color and Shape:SolidMolecular weight:269.73LY266097 hydrochloride
CAS:LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression research.Formula:C21H24Cl2N2O2Purity:99.63%Color and Shape:SolidMolecular weight:407.33Alosetron hydrochloride
CAS:Alosetron hydrochloride (GR 68755), a selective 5-HT3 receptor antagonist, can block the actions of serotonin at 5-HT3 sites in the peripheral nervous system.Formula:C17H19ClN4OPurity:99.90%Color and Shape:Off-White PowderMolecular weight:330.81(Rac)-WAY-161503
CAS:(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.Formula:C11H11Cl2N3OPurity:98.08%Color and Shape:SolidMolecular weight:272.13Org-13011 fumarate
CAS:Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.Formula:C22H29F3N4O5Purity:98.61%Color and Shape:SolidMolecular weight:486.48Azaphen dihydrochloride monohydrate
CAS:Azaphen dihydrochloride monohydrate is a 5-hydroxytryptamine reabsorption inhibitor with antidepressant activity and can be used to study neurological diseases.Formula:C16H23Cl2N5O2Purity:99.85%Color and Shape:SolidMolecular weight:388.29Metadoxine
CAS:Metadoxine (Metadoxil) is a neurotransmitter stimulant.Formula:C8H11NO3·C5H7NO3Purity:99.19%Color and Shape:Off-White PowderMolecular weight:298.29Geissoschizine methyl ether
CAS:Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.Formula:C22H26N2O3Purity:99.68% - 99.86%Color and Shape:SolidMolecular weight:366.45Ref: TM-TN1032
1mg137.00€5mg404.00€10mg587.00€25mg914.00€50mg1,225.00€100mg1,663.00€1mL*10mM (DMSO)375.00€Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Formula:C22H28FNO3Purity:98.94% - 99.95%Color and Shape:SolidMolecular weight:373.46Methiothepin maleate
CAS:Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.Formula:C24H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:472.62Tianeptine
CAS:Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂,具有抗抑郁、抗焦虑和神经保护作用,可用于缓解疼痛的研究。Formula:C21H25ClN2O4SPurity:99.04%Color and Shape:SolidMolecular weight:436.95SB 271046 hydrochloride
CAS:SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist and is > 200-fold selective over 55 other receptors, enzymes and ion channels.Formula:C20H22ClN3O3S2·HClPurity:99.57%Color and Shape:SolidMolecular weight:488.455-Methyltryptamine hydrochloride
CAS:5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.Formula:C11H15ClN2Purity:99.45%Color and Shape:SolidMolecular weight:210.703Dolasetron
CAS:Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.Formula:C19H20N2O3Purity:99.84% - 99.86%Color and Shape:White PowderMolecular weight:324.37Harmine hydrochloride
CAS:Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.Formula:C13H13ClN2OPurity:100% - 99.45%Color and Shape:Yellow To Slightly Green Crystalline PowderMolecular weight:248.71Almotriptan Malate
CAS:Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55A-582941 dihydrochloride
CAS:A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partialFormula:C17H22Cl2N4Purity:99.55%Color and Shape:SolidMolecular weight:353.29Ref: TM-T22016
1mg42.00€5mg88.00€10mg120.00€25mg235.00€50mg354.00€100mg533.00€200mg743.00€1mL*10mM (DMSO)87.00€
