5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColor and Shape:SolidMolecular weight:335.44AC-90179 HCl
CAS:AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.Formula:C23H31ClN2O2Purity:99.14%Color and Shape:SolidMolecular weight:402.96Ref: TM-T26543
1mg52.00€2mg74.00€5mg96.00€10mg137.00€25mg215.00€50mg391.00€100mg582.00€1mL*10mM (DMSO)127.00€Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formula:C16H20ClNOPurity:98.98% - 99.19%Color and Shape:SoildMolecular weight:277.79Ref: TM-T67956L
1mg97.00€5mg217.00€10mg325.00€25mg557.00€50mg797.00€100mg1,103.00€1mL*10mM (DMSO)208.00€Asenapine Maleate
CAS:Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually.Formula:C21H20ClNO5Purity:99.28%Color and Shape:SolidMolecular weight:401.84Ref: TM-T1951
5mg35.00€10mg51.00€25mg80.00€50mg96.00€100mg135.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)55.00€RS-127445
CAS:RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.Formula:C17H16FN3Purity:99.32%Color and Shape:SolidMolecular weight:281.33AVN-492
CAS:AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).Formula:C17H21N5O2SPurity:99.81%Color and Shape:SolidMolecular weight:359.45Ref: TM-T5179
1mg39.00€2mg49.00€5mg81.00€10mg120.00€25mg236.00€50mg354.00€100mg510.00€1mL*10mM (DMSO)89.00€Befiradol hydrochloride
CAS:Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formula:C20H23Cl2F2N3OPurity:99.1%Color and Shape:SolidMolecular weight:430.32Levodropropizine
CAS:Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.Formula:C13H20N2O2Purity:100% - 99.93%Color and Shape:White Or Off White Crystalline PowderMolecular weight:236.31R 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurity:98.55%Color and Shape:SolidMolecular weight:459.58AVN-322
CAS:AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment.Formula:C17H20ClN5O2SPurity:98.83%Color and Shape:SolidMolecular weight:393.89BW 723C86
CAS:BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.Formula:C16H19ClN2OSPurity:99.35%Color and Shape:SolidMolecular weight:322.85Pardoprunox
CAS:Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Formula:C12H15N3O2Purity:98%Color and Shape:SolidMolecular weight:233.27CI 169369
CAS:CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.Formula:C19H21ClN2SPurity:100%Color and Shape:SoildMolecular weight:344.9Paroxetine hydrochloride
CAS:Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formula:C19H21ClFNO3Purity:98% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:365.8265-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5Cannabidiolic acid methyl ester
CAS:Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formula:C23H32O4Color and Shape:SolidMolecular weight:372.5Nefazodone hydrochloride
CAS:Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.Formula:C25H33Cl2N5O2Purity:99% - 99.86%Color and Shape:White SolidMolecular weight:506.47Ref: TM-T3275
5mg47.00€10mg70.00€25mg120.00€50mg216.00€100mg325.00€200mg472.00€500mg775.00€1mL*10mM (DMSO)77.00€LY334370
CAS:LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nMFormula:C21H22FN3OPurity:99.32%Color and Shape:SolidMolecular weight:351.42CJ 033466
CAS:CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.Formula:C19H28ClN5OPurity:98.41%Color and Shape:SolidMolecular weight:377.91Ref: TM-T22671
1mg48.00€5mg101.00€10mg170.00€25mg270.00€50mg386.00€100mg520.00€1mL*10mM (DMSO)158.00€4-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.28Intepirdine
CAS:Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.Formula:C19H19N3O2SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:353.44Lesopitron HCl
CAS:Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.Formula:C15H22Cl2N6Purity:97.05% - 98.18%Color and Shape:SoildMolecular weight:357.28Minesapride
CAS:Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.Formula:C21H31ClN4O5Purity:99% - 99.35%Color and Shape:SolidMolecular weight:454.95Ref: TM-T28043L
1mg115.00€5mg245.00€10mg363.00€25mg562.00€50mg802.00€100mg1,111.00€200mg1,491.00€1mL*10mM (DMSO)284.00€LP44 hydrochloride
CAS:LP44 hydrochloride is a 5-HT7 agonist with analgesic effects on formalin-induced orofacial pain in mice and can be used to study neuroinflammation.Formula:C27H38ClN3OSPurity:98.06%Color and Shape:SolidMolecular weight:488.13Methiothepin mesylate
CAS:Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.Formula:C21H28N2O3S3Purity:98% - 99.92%Color and Shape:SolidMolecular weight:452.65Pheniramine maleate
CAS:Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formula:C16H20N2·C4H4O4Purity:99.85%Color and Shape:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CMolecular weight:356.42Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Formula:C16H20N2O2SColor and Shape:SolidMolecular weight:304.41Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formula:C22H23N3O3SPurity:98.60%Color and Shape:SolidMolecular weight:409.5Ref: TM-T30798
1mg81.00€5mg170.00€10mg274.00€25mg543.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)198.00€SEP-363856 hydrochloride
CAS:SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.Formula:C9H14ClNOSPurity:99.86% - 99.99%Color and Shape:SolidMolecular weight:219.73Ref: TM-T12899L
1mg70.00€2mg92.00€5mg154.00€10mg243.00€25mg425.00€50mg628.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)169.00€AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColor and Shape:SolidMolecular weight:268.78Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.23% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg145.00€2mg215.00€5mg314.00€10mg474.00€25mg808.00€50mg1,111.00€100mg1,501.00€1mL*10mM (DMSO)324.00€Serotonin
CAS:Serotonin (5-hydroxytryptamine) is a natural product from animalsFormula:C10H12N2OPurity:95.94% - 99.92%Color and Shape:SolidMolecular weight:176.22Ref: TM-TN2437
1mg78.00€5mg139.00€10mg202.00€25mg360.00€50mg540.00€100mg810.00€500mg1,596.00€1mL*10mM (DMSO)117.00€m-Chlorophenylbiguanide hydrochloride
CAS:m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.Formula:C8H11Cl2N5Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:248.11Viloxazine
CAS:Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFormula:C13H19NO3Purity:99.8%Color and Shape:SolidMolecular weight:237.29Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formula:C17H18F3NOPurity:99.07% - 99.28%Color and Shape:SolidMolecular weight:309.332-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Bromperidol
CAS:Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.Formula:C21H23BrFNO2Purity:99.89%Color and Shape:Tan SolidMolecular weight:420.32Cinitapride
CAS:Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.Formula:C21H30N4O4Purity:98.99%Color and Shape:SolidMolecular weight:402.49Ref: TM-T21385
1mg78.00€5mg163.00€10mg253.00€25mg505.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)187.00€p-MPPF
CAS:p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H27FN4O2Purity:99.79%Color and Shape:SolidMolecular weight:434.51Mirtazapine
CAS:Mirtazapine is a unique tetracyclic antidepressant, may cause temporary liver enzyme elevation, and is linked to rare liver injury.Formula:C17H19N3Purity:99.98%Color and Shape:SolidMolecular weight:265.35PRX933 hydrochloride
CAS:PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Formula:C16H22ClN5O2Purity:97.99% - 99.72%Color and Shape:SolidMolecular weight:351.84Ref: TM-T12565
1mg356.00€5mg568.00€10mg907.00€25mg1,339.00€50mg1,815.00€100mg2,432.00€1mL*10mM (DMSO)652.00€Iprindole
CAS:Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].Formula:C19H28N2Purity:99.06%Color and Shape:SolidMolecular weight:284.44Ref: TM-T37015
2mg37.00€5mg52.00€10mg80.00€25mg154.00€50mg266.00€100mg455.00€200mg652.00€1mL*10mM (DMSO)84.00€MDL 100009
CAS:MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Formula:C22H28FNO3Purity:98.96%Color and Shape:SolidMolecular weight:373.46Ref: TM-T22359
1mg148.00€2mg188.00€5mg283.00€10mg424.00€25mg655.00€50mg883.00€100mg1,169.00€200mg1,596.00€1mL*10mM (DMSO)335.00€Tropisetron
CAS:Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Formula:C17H20N2O2Purity:99.95%Color and Shape:White SolidMolecular weight:284.35Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Formula:C22H33FN2O2Color and Shape:SolidMolecular weight:376.51GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formula:C23H27N3O2Purity:99.9%Color and Shape:SolidMolecular weight:377.48Sertindole
CAS:Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formula:C24H26ClFN4OPurity:99.74%Color and Shape:Off-White To Pale Yellow SolidMolecular weight:440.94Xanthotoxol
CAS:Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.Formula:C11H6O4Purity:99.97%Color and Shape:SolidMolecular weight:202.16SKF-83566
CAS:SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Formula:C17H18BrNOPurity:95.00% - 99.82%Color and Shape:SolidMolecular weight:332.23
