5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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Azatadine dimaleate
CAS:Azatadine dimaleate (SCH10649) is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).Formula:C28H30N2O8Purity:100% - 99.70%Color and Shape:PowderMolecular weight:522.555-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67GR 113808
CAS:GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.Formula:C19H27N3O4SPurity:98.16%Color and Shape:SolidMolecular weight:393.5Pimavanserin
CAS:Pimavanserin is a potent 5-HT2A inverse agonist, used to treat Parkinson's psychosis.Formula:C25H34FN3O2Purity:97.84% - 99.69%Color and Shape:Pale Yellow To Pale Orange SolidMolecular weight:427.55Xaliproden hydrochloride
CAS:Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.Formula:C24H23ClF3NPurity:99.99%Color and Shape:SolidMolecular weight:417.89Ref: TM-T9272
1mg40.00€5mg85.00€10mg120.00€25mg235.00€50mg376.00€100mg540.00€200mg775.00€1mL*10mM (DMSO)96.00€PF-04995274
CAS:PF-04995274: potent, selective partial 5-HT4R agonist; EC50 0.26-0.47 nM; brain penetrant; may treat Alzheimer's cognitive issues.Formula:C23H32N2O6Purity:99.52%Color and Shape:SolidMolecular weight:432.51Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295Amperozide
CAS:Amperozide (FG 5606), an atypical antipsychotic, antagonizes 5-HT2A and modulates dopamine activity for schizophrenia treatment.Formula:C23H29F2N3OPurity:99.42%Color and Shape:SolidMolecular weight:401.49Ref: TM-T23733
1mg92.00€5mg188.00€10mg311.00€25mg525.00€50mg747.00€100mg1,017.00€500mg2,023.00€1mL*10mM (DMSO)339.00€Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formula:C38H44Cl2F2N2O7Purity:100%Color and Shape:SolidMolecular weight:749.67BRL-15572 dihydrochloride
CAS:BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.Formula:C25H27ClN2O·2HClPurity:99.74%Color and Shape:SolidMolecular weight:479.874-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formula:C10H15Cl2NColor and Shape:SolidMolecular weight:220.144F 4PP oxalate
CAS:4F 4PP oxalate is a 5-HT2A antagonist.Formula:C22H26FNO·C2H2O4Purity:97.34%Color and Shape:SolidMolecular weight:429.49Ref: TM-T22514
5mg46.00€10mg80.00€25mg131.00€50mg210.00€100mg313.00€200mg445.00€1mL*10mM (DMSO)49.00€Lintopride HCl
CAS:Lintopride HCl is a 5HT-4 antagonist.Formula:C14H20Cl2N4O2Purity:97.70% - 98.42%Color and Shape:SoildMolecular weight:347.24Ramosetron hydrochloride
CAS:Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.Formula:C17H18ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:315.8RS 42358-197
CAS:RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.Formula:C19H23ClN2OPurity:98.23%Color and Shape:SolidMolecular weight:330.85Ref: TM-T20739
1mg166.00€5mg371.00€10mg557.00€25mg827.00€50mg1,111.00€100mg1,491.00€200mg2,015.00€1mL*10mM (DMSO)369.00€Lesopitron dihydrochloride
CAS:Lesopitron dihydrochloride with IC50 of 125 nM in rat hippocampal membranes, is a full and selective 5-HT1A receptor agonist.Formula:C15H23Cl3N6Purity:98%Color and Shape:SolidMolecular weight:393.74RS 56812
CAS:RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formula:C18H21N3O2Purity:98.78%Color and Shape:SoildMolecular weight:311.38Eptapirone
CAS:Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.Formula:C16H23N7O2Purity:99.39% - 99.65%Color and Shape:SolidMolecular weight:345.4Talipexole dihydrochloride
CAS:Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical andFormula:C10H17Cl2N3SPurity:98.64%Color and Shape:Light Yellow SolidMolecular weight:282.23Ref: TM-T14490
2mg38.00€5mg56.00€10mg89.00€25mg154.00€50mg264.00€100mg424.00€200mg613.00€500mg949.00€1mL*10mM (DMSO)63.00€RS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purity:98.95%Color and Shape:SolidMolecular weight:426.86(-)-5-HT2C agonist-3
CAS:Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.Formula:C19H23ClFNO2Color and Shape:SolidMolecular weight:351.84SCH-23390 maleate
CAS:SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.864i
CAS:4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.Formula:C16H12ClN3OPurity:99.49%Color and Shape:SolidMolecular weight:297.74Flibanserin
CAS:Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.Formula:C20H21F3N4OPurity:99.37% - 99.93%Color and Shape:White PowderMolecular weight:390.4Flopropione
CAS:Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.Formula:C9H10O4Purity:99.93%Color and Shape:SolidMolecular weight:182.17PRX-08066 Maleic acid
CAS:PRX-08066 Maleic acid is the salt form of PRX-08066.PRX-08066 is a 5-HT receptor 2B antagonist that induces selective vasodilation of the pulmonary artery.Formula:C23H21ClFN5O4SPurity:97.59%Color and Shape:SolidMolecular weight:517.96Ref: TM-T6959
1mg90.00€5mg186.00€10mg252.00€25mg454.00€50mg660.00€100mg939.00€200mg1,276.00€1mL*10mM (DMSO)435.00€SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formula:C17H19Cl2NOPurity:98% - 99.51%Color and Shape:SolidMolecular weight:324.24Ref: TM-T4369
1mg39.00€2mg50.00€5mg78.00€10mg97.00€25mg195.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)78.00€F13714 fumarate
CAS:F13714 fumarate is a 5-HT1A receptor-biased agonist.Formula:C25H29ClF2N4O5Purity:98.86%Color and Shape:SolidMolecular weight:538.975-Carboxamidotryptamine maleate
CAS:5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.Formula:C15H17N3O5Purity:97.77%Color and Shape:SolidMolecular weight:319.316-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Color and Shape:SolidMolecular weight:234.31SEP-363856 mesylate
CAS:SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.Formula:C10H17NO4S2Color and Shape:SolidMolecular weight:279.38AAZ-A 154 mesylate
CAS:AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.Formula:C15H24N2O4SColor and Shape:SolidMolecular weight:328.43Ondansetron hydrochloride
CAS:Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiationFormula:C18H19N3O·HClPurity:99.78%Color and Shape:White PowderMolecular weight:329.8225B-NBOH hydrochloride
CAS:25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.Formula:C17H21BrClNO3Color and Shape:SolidMolecular weight:402.711SB-203186 hydrochloride
CAS:SB 203186 hydrochloride is a potent 5-HT4 receptor antagonistFormula:C16H20N2O2·HClPurity:99.64%Color and Shape:SolidMolecular weight:308.81Loxapine succinate
CAS:Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.Formula:C22H24ClN3O5Purity:99.69%Color and Shape:White To Of-White SolidMolecular weight:445.9Lecozotan HCl
CAS:Lecozotan HCl is a selective 5-HT antagonist boosting glutamate and acetylcholine release without causing 5-HT(1A) tolerance.Formula:C28H30ClN5O3Purity:99.47%Color and Shape:SolidMolecular weight:520.02QF0301B
CAS:QF0301B is a potent α1-adrenergic receptor antagonist with inhibitory effects on α2-adrenergic receptors, 5-HT2A and histamine H1 receptors.Formula:C23H28N2O2Purity:99.16%Color and Shape:SolidMolecular weight:364.48Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Purity:98%Color and Shape:SolidMolecular weight:N/ADapoxetine
CAS:Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formula:C21H23NOPurity:99.73%Color and Shape:White To Off-White Crystalline PowderMolecular weight:305.42Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurity:99.78%Color and Shape:SolidMolecular weight:425.52Ref: TM-T15270
2mg42.00€5mg56.00€10mg81.00€25mg116.00€50mg170.00€100mg250.00€200mg369.00€1mL*10mM (DMSO)62.00€Pimavanserin tartrate
CAS:Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.Formula:C50H68F2N6O4·C4H6O6Purity:100% - 99.98%Color and Shape:SolidMolecular weight:1005.2Ziprasidone
CAS:Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.Formula:C21H21ClN4OSPurity:100% - 99.53%Color and Shape:Tan SolidMolecular weight:412.94GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Color and Shape:SolidMolecular weight:504.59Anpirtoline hydrochloride
CAS:Anpirtoline hydrochloride (D-16949 hydrochloride) is a 5-HT1B receptor agonist and 5-HT3 receptor antagonist used in the study of dyskinesia.Formula:C10H14Cl2N2SPurity:100% - 100%Color and Shape:SolidMolecular weight:265.20Quetiapine hemifumarate
CAS:Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.Formula:C46H54N6O8S2Purity:100% - 99.59%Color and Shape:White Crystalline SolidMolecular weight:883.09Agomelatine
CAS:Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.Formula:C15H17NO2Purity:99.92%Color and Shape:White SolidMolecular weight:243.3Rizatriptan benzoate
CAS:Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraineFormula:C22H25N5O2Purity:99% - 99.72%Color and Shape:White To Off-White Crystalline PowderMolecular weight:391.47Ref: TM-T1512
10mg47.00€25mg79.00€50mg126.00€100mg183.00€200mg273.00€500mg462.00€1mL*10mM (DMSO)50.00€Ansofaxine hydrochloride
CAS:Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).Formula:C24H32ClNO3Purity:99.57% - 99.77%Color and Shape:SolidMolecular weight:417.97
