GlyT
Glycine Transporter (GlyT) inhibitors are compounds that block the reuptake of glycine, an important inhibitory neurotransmitter in the spinal cord and brainstem. By inhibiting glycine transporters, these compounds increase the availability of glycine in the synaptic cleft, enhancing its inhibitory effects on neuronal activity. GlyT inhibitors are of interest for their potential therapeutic applications in conditions like chronic pain, spasticity, and schizophrenia. At CymitQuimica, we provide GlyT inhibitors to support your research in pain management, motor control, and neuropsychiatric disorders.
Products of "GlyT"
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Found 13 products on this category.
Iclepertin
CAS:Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Formula:C20H18F6N2O5SPurity:98.89% - 98.93%Color and Shape:SolidMolecular weight:512.42Ref: TM-T37089
1mg159.00€5mg271.00€10mg373.00€25mg612.00€50mg920.00€100mg1,378.00€200mg1,863.00€1mL*10mM (DMSO)306.00€ASP2535
CAS:ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitiveFormula:C22H18N6OPurity:98%Color and Shape:SolidMolecular weight:382.42Sarcosine
CAS:Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.Formula:C3H7NO2Purity:99.90%Color and Shape:Deliquescent Water Soluble Physical Description Deliquescent Crystals Or Powder Has A Sweetish Taste (Ntp 1992)Molecular weight:89.09Opiranserin
CAS:Opiranserin is a development as an injectable agent for the treatment of postoperative pain.Formula:C21H34N2O5Purity:98%Color and Shape:SolidMolecular weight:394.51PF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNSFormula:C19H22ClFN4OPurity:99.86%Color and Shape:LiquidMolecular weight:376.86ALX-1393
CAS:ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits theFormula:C23H22FNO4Purity:99.73%Color and Shape:SolidMolecular weight:395.42Ref: TM-T14198
1mg1,311.00€5mg2,660.00€10mg3,591.00€25mg5,339.00€50mg7,210.00€100mg9,377.00€1mL*10mM (DMSO)2,737.00€Amoxapine
CAS:Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerveFormula:C17H16ClN3OPurity:98.80% - 98.84%Color and Shape:SolidMolecular weight:313.78Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFormula:C21H35ClN2O5Purity:98.03%Color and Shape:SolidMolecular weight:430.97Ref: TM-T9833
1mg96.00€5mg227.00€10mg359.00€25mg652.00€50mg929.00€100mg1,293.00€500mg2,593.00€1mL*10mM (DMSO)250.00€Tilapertin
CAS:Tilapertin is an oral glycine transporter type-1 inhibitor.Formula:C20H21F3N2O2Purity:98%Color and Shape:SolidMolecular weight:378.39Bitopertin
CAS:Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nMFormula:C21H20F7N3O4SPurity:98.57% - 98.71%Color and Shape:SolidMolecular weight:543.46GlyT1 Inhibitor 1
CAS:GlyT1 Inhibitor 1 is a selective and potent GlyT1 inhibitor, inhibiting rGlyT1, used in research on neurological disorders.Formula:C22H21N5O2Color and Shape:SolidMolecular weight:387.43LY2365109 hydrochloride
CAS:LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.Formula:C22H28ClNO5Purity:99.47%Color and Shape:SolidMolecular weight:421.91Ref: TM-T11908
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg235.00€50mg354.00€100mg512.00€1mL*10mM (DMSO)87.00€Bitopertin (R enantiomer)
CAS:Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin.Formula:C21H20F7N3O4SPurity:98%Color and Shape:SolidMolecular weight:543.46
