Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Products of "Beta Amyloid"
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BMS 299897
CAS:BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.Formula:C24H21ClF3NO4SPurity:100%Color and Shape:SolidMolecular weight:511.94MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Formula:C18H24N2O2Purity:99.88%Color and Shape:SolidMolecular weight:300.4Ref: TM-T60671
1mg37.00€5mg81.00€10mg116.00€25mg235.00€50mg335.00€100mg487.00€200mg662.00€1mL*10mM (DMSO)255.00€Lecanemab
CAS:Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.Purity:95%Color and Shape:LiquidEdonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Formula:C20H25NO6SPurity:98.24%Color and Shape:SolidMolecular weight:407.48Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:100% - 99.78%Color and Shape:White PowderMolecular weight:947.15MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Formula:C14H9FN4OPurity:98.54% - 99.82%Color and Shape:SolidMolecular weight:268.25Ref: TM-T16094
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Formula:C19H27N3O4Purity:97.1% - 99.11%Color and Shape:SolidMolecular weight:361.44Begacestat
CAS:Begacestat is a selective thiophene sulfonamide amyloid precursor protein gamma-secretase inhibitor (Aβ40,IC50=15 nM),and for the treatment of Alzheimer'sFormula:C9H8ClF6NO3S2Color and Shape:SolidMolecular weight:391.74Hematoxylin
CAS:Hematoxylin, a dye from logwood heartwood, stains slides and makes ink.Formula:C16H14O6Purity:97.09%Color and Shape:Physical Description White To Yellowish Crystals That Redden On Exposure To Light (Ntp 1992)Molecular weight:302.288-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFormula:C23H24O5Purity:99.04% - 99.76%Color and Shape:SolidMolecular weight:380.43ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurity:99.52%Color and Shape:SolidMolecular weight:200.24Ref: TM-T7490
1mg37.00€5mg79.00€10mg119.00€25mg235.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)87.00€Crenezumab
CAS:Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.Purity:95% - 95%Color and Shape:LiquidMK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).Formula:C21H21ClF2O4SPurity:98% - 99.55%Color and Shape:SolidMolecular weight:442.9Semilicoisoflavone B
CAS:Semilicoisoflavone B is an isoflavone extracted from Kohlrabi with anticancer activity.Formula:C20H16O6Purity:98%Color and Shape:SolidMolecular weight:352.34Rutin
CAS:Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, andFormula:C27H30O16Purity:95.66% - 97.19%Color and Shape:SolidMolecular weight:610.52Putraflavone
CAS:Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.Formula:C32H22O10Purity:98%Color and Shape:SolidMolecular weight:566.51δ-secretase inhibitor 11
CAS:δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.Formula:C10H12N4O2Purity:99.4%Color and Shape:SolidMolecular weight:220.23Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFormula:C16H11BrN2O2Purity:98.88% - 99.53%Color and Shape:SolidMolecular weight:343.17RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Formula:C22H20F5N3O3Purity:98.50% - 99.51%Color and Shape:SolidMolecular weight:469.4Trontinemab
CAS:Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).Purity:96.77%Color and Shape:LiquidSchisantherin B
CAS:1.Formula:C28H34O9Purity:99% - 99.06%Color and Shape:SolidMolecular weight:514.56Ref: TM-T6S1918
1mg52.00€5mg108.00€10mg162.00€25mg250.00€50mg344.00€100mg512.00€1mL*10mM (DMSO)138.00€Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purity:98.99%Color and Shape:SolidMolecular weight:449.5PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Formula:C28H24N4O2Purity:98.8% - 99.09%Color and Shape:SolidMolecular weight:448.52Ref: TM-T4077
1mg66.00€5mg144.00€10mg216.00€25mg406.00€50mg648.00€100mg1,008.00€1mL*10mM (DMSO)159.00€LY2811376
CAS:LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).Formula:C15H14F2N4SPurity:99% - 99.01%Color and Shape:SolidMolecular weight:320.36Ref: TM-T2639
1mg52.00€2mg73.00€5mg123.00€10mg205.00€25mg374.00€50mg560.00€100mg800.00€1mL*10mM (DMSO)123.00€4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22BSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Formula:C24H17BrO6Purity:95.53%Color and Shape:SolidMolecular weight:481.29(+)-Medioresinol
CAS:(+)-Medioresinol has antioxidant, anti-leishmania, and heart health benefits; it reduces α2-secretase for Alzheimer's prevention and treats infections.Formula:C21H24O7Purity:98%Color and Shape:SolidMolecular weight:388.41Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Formula:C25H48N6O8S2Purity:99.87%Color and Shape:SolidMolecular weight:624.81ALZ-801
CAS:ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.Formula:C8H18N2O4SPurity:99.36%Color and Shape:SolidMolecular weight:238.3Donanemab
CAS:Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Purity:95%Color and Shape:LiquidGantenerumab
CAS:Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.Purity:>95%Color and Shape:LiquidPinostrobin
CAS:Pinostrobin protects PC12 cells from Aβ25-35 neurotoxicity by reducing oxidative stress, calcium excess, and blocking cell death pathways.Formula:C16H14O4Purity:99.35% - 99.55%Color and Shape:SolidMolecular weight:270.28Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Formula:C36H45N5O8SPurity:98.9% - 99.65%Color and Shape:SolidMolecular weight:707.84Ref: TM-T11043
1mg52.00€5mg119.00€10mg187.00€25mg315.00€50mg470.00€100mg642.00€1mL*10mM (DMSO)182.00€PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Formula:C23H27NO4Purity:99.31%Color and Shape:SolidMolecular weight:381.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFormula:C30H44N2O14Purity:98.03%Color and Shape:SolidMolecular weight:656.68Ref: TM-T14283
2mg46.00€5mg66.00€10mg97.00€25mg173.00€50mg283.00€100mg452.00€500mg938.00€1mL*10mM (DMSO)96.00€Buntanetap
CAS:Buntanetap ((+)-Phenserine) is an inhibitor of TINAPs used in the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseaseFormula:C20H23N3O2Purity:98.2%Color and Shape:SolidMolecular weight:337.42Ref: TM-T17312
1mg187.00€5mg472.00€10mg753.00€25mg1,406.00€50mg2,043.00€100mg2,660.00€1mL*10mM (DMSO)518.00€Rutin hydrate
CAS:Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formula:C27H32O17Purity:97.23%Color and Shape:SolidMolecular weight:628.53Birtamimab
CAS:Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.Purity:>95%Color and Shape:LiquidTABERSONINE HYDROCHLORIDE
CAS:TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.Formula:C21H25ClN2O2Purity:98.17%Color and Shape:SolidMolecular weight:372.89Cedrin
CAS:Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidativeFormula:C16H14O8Purity:98%Color and Shape:SolidMolecular weight:334.28LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurity:99.45%Color and Shape:SolidMolecular weight:474.91Ref: TM-T4398
2mg37.00€5mg52.00€10mg84.00€25mg137.00€50mg229.00€100mg340.00€200mg472.00€1mL*10mM (DMSO)58.00€β-Amyrin
CAS:β-Amyrin (beta-Amyrin) has antiviral, hepatoprotective, antinociceptive, anti-inflammatoryFormula:C30H50OPurity:96.49%Color and Shape:White Crystalline PowderMolecular weight:426.72BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.Formula:C21H20F2N4O4Purity:99.17%Color and Shape:SolidMolecular weight:430.4LY 2389575 hydrochloride
CAS:LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Formula:C15H16BrCl3N4Purity:100%Color and Shape:SolidMolecular weight:438.58Saikosaponin C
CAS:Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.Formula:C48H78O17Purity:98% - 99.94%Color and Shape:SolidMolecular weight:927.12Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Formula:C42H72O13Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:785.01Ref: TM-T2873
2mg37.00€5mg52.00€10mg88.00€25mg131.00€50mg188.00€100mg279.00€500mg658.00€1mL*10mM (DMSO)87.00€Azeliragon
CAS:Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-Formula:C32H38ClN3O2Purity:96.7% - 98.32%Color and Shape:SolidMolecular weight:532.12FPS-ZM1
CAS:FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.Formula:C20H22ClNOPurity:98.39% - 99.3%Color and Shape:SolidMolecular weight:327.85Ref: TM-T3259
5mg50.00€10mg57.00€25mg92.00€50mg147.00€100mg220.00€200mg350.00€500mg590.00€1mL*10mM (DMSO)52.00€MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Formula:C20H22O4Purity:98.57%Color and Shape:SolidMolecular weight:326.39
