Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Products of "Beta Amyloid"
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Hederacolchiside E
CAS:Hederacolchiside E: antioxidant, neuroprotective in AD, reduces oxidative stress, inhibits lipid peroxidation.Formula:C65H106O30Purity:99.78%Color and Shape:SolidMolecular weight:1367.52Scyllo-Inositol
CAS:Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent forFormula:C6H12O6Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:180.16Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Formula:C20H28N6OPurity:98.51%Color and Shape:SolidMolecular weight:368.48Ref: TM-T4364
2mg42.00€5mg80.00€10mg116.00€25mg226.00€50mg335.00€100mg480.00€200mg652.00€1mL*10mM (DMSO)64.00€Tramiprosate
CAS:Tramiprosate (Alzhemed) is an orally active, BBB-crossing, naturally occurring amino acid that binds soluble Aβ and maintains it in a non-protofibrillar form.Formula:C3H9NO3SPurity:99%Color and Shape:White Crystals Or Crystalline PowerMolecular weight:139.17Mirabijalone D
CAS:Mirabijalone D is a non-competitive inhibitor based on the Dixon plot.It inhibits Aβ1-42 production by 43.7% in APPSW-N2a cells.Formula:C18H14O7Purity:98%Color and Shape:SolidMolecular weight:342.3EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purity:98.39%Color and Shape:SolidMolecular weight:416.74Ref: TM-T6495
10mg35.00€25mg66.00€50mg104.00€100mg160.00€200mg230.00€500mg378.00€1mL*10mM (DMSO)47.00€1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。Formula:C26H34N2O7Purity:99.44%Color and Shape:SoildMolecular weight:486.56Ref: TM-T67751
1mg313.00€5mg758.00€10mg1,035.00€25mg1,568.00€50mg2,118.00€100mg2,783.00€1mL*10mM (DMSO)945.00€C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.Formula:C39H51I3N6O9Purity:≥95%Color and Shape:SolidMolecular weight:1128.57Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Formula:C6H10CuN6S2Purity:99.21%Color and Shape:SolidMolecular weight:293.86Ref: TM-T40792
1mg38.00€5mg80.00€10mg126.00€25mg277.00€50mg472.00€100mg790.00€200mg1,074.00€1mL*10mM (DMSO)87.00€Isorosmanol
CAS:Isorosmanol has antioxidant, neuroprotective properties, and may aid aging-related cognitive decline and hyperpigmentation.Formula:C20H26O5Purity:98.85%Color and Shape:SolidMolecular weight:346.42Itanapraced
CAS:Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).Formula:C16H11Cl2FO2Purity:98% - 99.79%Color and Shape:SolidMolecular weight:325.16Aducanumab
CAS:Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.Purity:95% - 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.93 kDaHoechst 34580 xHCl(23555-00-2(free base)
Hoechst 34580 xHCl(23555-00-2(free base) is a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Formula:C27H29N7·xHClPurity:98.89%Color and Shape:SolidMolecular weight:N/APPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purity:95.16% - 97.21%Color and Shape:SolidMolecular weight:650.85Methyl tridecanoate
CAS:Methyl tridecanoate inhibits β-amyloid aggregation moderately and inhibits acetylcholinesterase (AChE) weekly[1].Formula:C14H28O2Purity:97.63%Color and Shape:LiquidMolecular weight:228.37DSS30
CAS:DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.Formula:C16H14ClNO3S2Purity:100% - 99.61%Color and Shape:SolidMolecular weight:367.87Ref: TM-T61439
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFormula:C27H33IN2Purity:99.57%Color and Shape:SolidMolecular weight:512.47DC-Chol hydrochloride
CAS:DC-Chol hydrochloride hinders Aβ40 fibrils and amyloid from oxidized hCT; boosts balanced immunity for hepatitis B vaccine studies.Formula:C32H57ClN2O2Purity:99.8%Color and Shape:SolidMolecular weight:537.26γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Formula:C27H24F2N4O3Purity:99.56%Color and Shape:SolidMolecular weight:490.5Ref: TM-T3521
1mg127.00€5mg406.00€10mg685.00€25mg1,359.00€50mg1,833.00€100mg2,452.00€1mL*10mM (DMSO)462.00€Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFormula:C15H13N3O2SPurity:99.82%Color and Shape:SolidMolecular weight:299.35Hoechst 34580
CAS:Hoechst 34580 (HOE 34580), a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Formula:C27H29N7Color and Shape:SolidMolecular weight:451.57Thiethylperazine
CAS:Thiethylperazine (Tietilperazina) is a D2 receptor and H1 receptor antagonist, and an ABCC1 activator with antimicrobial and antiemetic activity.Formula:C22H29N3S2Purity:98.72%Color and Shape:SolidMolecular weight:399.62Licochalcone B
CAS:Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.Formula:C16H14O5Purity:99.33% - 99.93%Color and Shape:SolidMolecular weight:286.28Ref: TM-T4S0350
1mg52.00€5mg117.00€10mg188.00€25mg329.00€50mg490.00€100mg710.00€1mL*10mM (DMSO)140.00€BACE1-IN-5
CAS:BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) & Aβ production (IC50: 0.82 nM), enhances hERG inhibition & P-gp efflux.Formula:C18H16F5N5O2SPurity:98%Color and Shape:SolidMolecular weight:461.41Geniposide
CAS:Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidativeFormula:C17H24O10Purity:99.17% - 99.54%Color and Shape:SolidMolecular weight:388.377-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
CAS:7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, andFormula:C19H20O2Purity:98%Color and Shape:SolidMolecular weight:280.36Schisandrone
CAS:Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.Formula:C21H24O5Purity:99.84%Color and Shape:SolidMolecular weight:356.41
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