Adrenergic Receptor

(±)-Penbutolol ((Rac)-Penbutolol) is the racemic form of Penbutolol. It acts as an orally active β-adrenergic receptor antagonist. (±)-Penbutolol mitigates the tachycardia induced by exercise, reduces the increase in peak expiratory flow rate (PEFR) caused by physical activity, and decreases plasma renin activity (PRA) at rest. The peak plasma concentration of this compound is achieved one hour after oral administration, with a half-life of 4.5 hours, and it is metabolized into active metabolites in the body. This compound is utilized in research related to cardiovascular diseases.

Metaproterenol hemisulfate (Orciprenaline sulfate) is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.

Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.

Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.

Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。

Saterinone: PDE III inhibitor, α-1-adrenoceptor antagonist, vasodilator, used for acute chronic heart failure, IC50 2.3x10^-5 M.

Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity.

Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.

Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol.

DL-071-IT (Afurolol Hydrochloride) is a potent non-selective beta-adrenoceptor antagonist.

Levalbuterol tartrate is a short-acting β2-adrenergic receptor agonist and the R enantiomer of salbutamol.Cost-effective and quality-assured.

Ritodrine hydrochloride (NSC 291565), a phenethylamine derivative, reduces uterine contractions by increasing cAMP and decreasing calcium in myometrial cells.

napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the

Midodrine, metabolized to desglymidodrine, activates alpha-1 receptors, raising blood pressure without CNS effects. It's a prodrug in hydrochloride form.

T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-

L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benign

Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).

Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.