Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Benzydamine hydrochloride
CAS:Formula:C19H24ClN3OPurity:97%Color and Shape:SolidMolecular weight:345.8664Nimesulide
CAS:Formula:C13H12N2O5SPurity:>98.0%(T)(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:308.31Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purity:100% - 99.8%Color and Shape:SolidMolecular weight:954.66Ref: TM-TQ0180
1mg79.00€5mg165.00€10mg238.00€25mg398.00€50mg592.00€100mg842.00€1mL*10mM (DMSO)256.00€Pasiniazid
CAS:Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.Formula:C13H14N4O4Purity:100% - 97.68%Color and Shape:CoaMolecular weight:290.28EIPA
CAS:EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formula:C11H18ClN7OPurity:96.62% - 98.52%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76Ketorolac Tromethamine
CAS:Formula:C15H13NO3·C4H11NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:376.41Valdecoxib
CAS:Valdecoxib (SC 65872), an NSAID, treats osteoarthritis, rheumatoid arthritis, and menstrual pain. Not for NSAID allergies.Formula:C16H14N2O3SPurity:97.66% - 99.37%Color and Shape:White Crystalline PowderMolecular weight:314.36Ref: TM-T0219
2mg46.00€5mg65.00€10mg88.00€25mg187.00€50mg329.00€100mg509.00€200mg730.00€1mL*10mM (DMSO)59.00€Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-
CAS:Formula:C19H18N2O4SPurity:98%Color and Shape:SolidMolecular weight:370.4222Acetaminophen
CAS:Acetaminophen: pain reliever, fever reducer; mild anti-inflammatory. Risks: liver, kidney damage, blood cell effects.Formula:C8H9NO2Purity:100% - 99.99%Color and Shape:Colourless Solid CrystallineMolecular weight:151.16Suprofen
CAS:Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic.Formula:C14H12O3SPurity:99.14% - 99.33%Color and Shape:SolidMolecular weight:260.312-(11-Oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid
CAS:Formula:C16H12O4Purity:98%Color and Shape:SolidMolecular weight:268.2641Lobuprofen
CAS:Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.Formula:C25H33ClN2O2Purity:99.09%Color and Shape:SolidMolecular weight:428.992(5H)-Furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-
CAS:Formula:C17H14O4SPurity:99%Color and Shape:SolidMolecular weight:314.3557Bufexamac
CAS:Formula:C12H17NO3Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:223.27Mofezolac
CAS:Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000Formula:C19H17NO5Purity:99.29%Color and Shape:SolidMolecular weight:339.34Ampyrone
CAS:Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.Formula:C11H13N3OPurity:98.41% - 98.58%Color and Shape:Pale Yellow CrystalsMolecular weight:203.24ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21COX-1/2-IN-4
COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.Formula:C22H24N2O2SPurity:98%Color and Shape:SolidMolecular weight:380.51H-Pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)-
CAS:Formula:C15H15NO3Purity:95%Color and Shape:SolidMolecular weight:257.2845CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Formula:C20H28O3Purity:97.06% - 99.08%Color and Shape:SolidMolecular weight:316.432,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS:Formula:C18H15ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:358.8419Lumiracoxib
CAS:Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.Formula:C15H13ClFNO2Purity:96.64% - 99.25%Color and Shape:Pale Yellow SolidMolecular weight:293.72NS-398
CAS:NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.Formula:C13H18N2O5SPurity:99% - 99.72%Color and Shape:SolidMolecular weight:314.36Ref: TM-T3214
2mg35.00€5mg50.00€10mg66.00€25mg96.00€50mg177.00€100mg274.00€200mg355.00€1mL*10mM (DMSO)56.00€5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
CAS:Formula:C14H12O3Purity:98%Color and Shape:SolidMolecular weight:228.24328Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.4Esculentoside A
CAS:Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.Formula:C42H66O16Purity:98% - 99.85%Color and Shape:SolidMolecular weight:826.96MECLOFENAMATE SODIUM
CAS:Formula:C14H11Cl2NNaO2Purity:99%Color and Shape:SolidMolecular weight:319.1384γ-Tocopherol
CAS:(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.Formula:C28H48O2Purity:99.31% - 99.39%Color and Shape:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightMolecular weight:416.68Indomethacin
CAS:Formula:C19H16ClNO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:357.79(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid
CAS:Formula:C14H14O3Purity:>99.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:230.26Isofraxidin
CAS:Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.Formula:C11H10O5Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:222.19Ketorolac tromethamine salt
CAS:Ketorolac tromethamine salt (Ketorolac tris salt) non-selective inhibits the enzymes cyclooxygenase 1 (COX-1) and COX-2with anti-inflammatory, analgesic, andFormula:C19H24N2O6Purity:99.48% - 99.85%Color and Shape:CrystallineMolecular weight:376.42,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Apyramide
CAS:Apyramide, an NSAID and prodrug of indomethacin, inhibits COX1/COX2 and permeates the blood-brain barrier.Formula:C27H23ClN2O5Purity:98.99%Color and Shape:SolidMolecular weight:490.93Ref: TM-T10355
1mg35.00€5mg65.00€10mg101.00€25mg170.00€50mg248.00€100mg338.00€200mg460.00€1mL*10mM (DMSO)90.00€SC-75416
CAS:SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.Formula:C15H14ClF3O3Purity:98.67% - 98.67%Color and Shape:SolidMolecular weight:334.72Ibuprofen
CAS:Ibuprofen, an NSAID, reduces pain, inflammation, and fever by limiting prostaglandin production.Formula:C13H18O2Purity:99.7% - 99.81%Color and Shape:Colorless Solid CrystallineMolecular weight:206.28Tolmetin
CAS:Formula:C15H15NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:257.29Fenoprofen Calcium Salt Dihydrate
CAS:Formula:C30H26CaO6·2H2OPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:558.64Acemetacin
CAS:Formula:C21H18ClNO6Purity:>98.0%(GC)(T)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:415.83STAT1/3-IN-1
CAS:STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, without significant cytotoxicity.Formula:C28H25ClN6O5Color and Shape:SolidMolecular weight:560.988Metamizole sodium
CAS:Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.Formula:C13H16N3NaO4SPurity:99.52%Color and Shape:White Or Almost White Crystal PowderMolecular weight:333.34Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formula:C14H9ClN2O3SPurity:98.36% - 99.42%Color and Shape:SolidMolecular weight:320.75Indoprofen
CAS:Indoprofen ((±)-Indoprofe) is a non-steroidal anti-inflammatory drug.Formula:C17H15NO3Purity:100%Color and Shape:SolidMolecular weight:281.31Nabumetone
CAS:Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.Formula:C15H16O2Purity:97.59% - 99.61%Color and Shape:White /Almost White Crystalline PowderMolecular weight:228.29Cis-5-Dodecenoic Acid
CAS:Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.Formula:C12H22O2Purity:98% - 99.37%Color and Shape:SolidMolecular weight:198.3Paradol
CAS:Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.Formula:C17H26O3Purity:98.65% - 98.98%Color and Shape:SolidMolecular weight:278.39Floctafenine
CAS:Floctafenine (R-4318) is a non-steroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor with analgesic activity for the study of pain.Formula:C20H17F3N2O4Purity:98.65%Color and Shape:SolidMolecular weight:406.36
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