Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
Sort by
Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.7Pemedolac
CAS:Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.Formula:C22H23NO3Purity:100%Color and Shape:SolidMolecular weight:349.42syringaldehyde
CAS:Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.Formula:C9H10O4Purity:99.24%Color and Shape:Light Yellow-Green To Brown Crystalline PowderMolecular weight:182.17Ampiroxicam
CAS:Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.Formula:C20H21N3O7SPurity:97.27% - 99.2%Color and Shape:PowderMolecular weight:447.46Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Neral
CAS:Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.Formula:C10H16OColor and Shape:SolidMolecular weight:152.23S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.26Ibuprofen Lysine
CAS:Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formula:C19H32N2O4Purity:99.66%Color and Shape:CoaMolecular weight:352.47Carprofen
CAS:Formula:C15H12ClNO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:273.72Flunixin meglumine
CAS:Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.Formula:C21H28F3N3O7Purity:100% - 99.86%Color and Shape:SolidMolecular weight:491.46COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.Formula:C28H19F2N3SColor and Shape:SolidMolecular weight:467.53DuP-697
CAS:DuP-697 is an irreversible, specific COX-2 inhibitor with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1.Cost-effective and quality-assured.Formula:C17H12BrFO2S2Purity:100%Color and Shape:SolidMolecular weight:411.31Ref: TM-T15181
1mg52.00€5mg104.00€10mg154.00€25mg249.00€50mg369.00€100mg543.00€200mg772.00€1mL*10mM (DMSO)124.00€Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
CAS:Formula:C18H18F3NO2Purity:>98.0%(HPLC)(N)Color and Shape:Colorless to Yellow clear liquidMolecular weight:337.34Diclofenac Sodium Salt
CAS:Formula:C14H10Cl2NNaO2Purity:98%Color and Shape:SolidMolecular weight:318.13052-O-Sinapoyl makisterone A
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectivelyFormula:C39H56O11Purity:98%Color and Shape:SolidMolecular weight:700.86Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formula:C20H20ClN3O3Purity:99.03%Color and Shape:SolidMolecular weight:385.84Ref: TM-T7724
1mg56.00€5mg119.00€10mg170.00€25mg393.00€50mg587.00€100mg835.00€200mg1,130.00€1mL*10mM (DMSO)139.00€Byakangelicol
CAS:Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.Formula:C17H16O6Purity:99.15% - 99.55%Color and Shape:SolidMolecular weight:316.31Salicylic acid
CAS:Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formula:C7H6O3Purity:98.04% - 98.83%Color and Shape:White Solid PowderMolecular weight:138.12RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Formula:C20H34N4O4Purity:99.54%Color and Shape:White SolidMolecular weight:394.51Crocin II
CAS:Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.Formula:C38H54O19Purity:98% - 99.19%Color and Shape:SolidMolecular weight:814.82β-Amyrone
CAS:beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.Formula:C30H48OPurity:99.55%Color and Shape:SolidMolecular weight:424.7FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31Ref: TM-T8356
1mg40.00€5mg80.00€10mg116.00€25mg198.00€50mg299.00€100mg449.00€200mg627.00€1mL*10mM (DMSO)99.00€Eltenac
CAS:Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.Formula:C12H9Cl2NO2SPurity:98.78%Color and Shape:SolidMolecular weight:302.18Chlorotrianisene
CAS:Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.Formula:C23H21ClO3Purity:98.88% - 99.03%Color and Shape:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Molecular weight:380.86Ref: TM-T2569
1mg59.00€5mg127.00€10mg205.00€25mg344.00€50mg512.00€100mg730.00€200mg998.00€1mL*10mM (DMSO)139.00€FK 3311
CAS:FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (Formula:C15H13F2NO4SPurity:97.98%Color and Shape:SolidMolecular weight:341.33Ref: TM-T7207
2mg46.00€5mg66.00€10mg96.00€25mg165.00€50mg250.00€100mg374.00€200mg547.00€1mL*10mM (DMSO)88.00€Diclofenac Diethylamine
CAS:Formula:C14H11Cl2NO2·C4H11NPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:369.29[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formula:C19H28O3Purity:97.01%Color and Shape:SolidMolecular weight:304.42Ref: TM-T5430
1mg96.00€5mg208.00€10mg359.00€25mg592.00€50mg837.00€100mg1,121.00€1mL*10mM (DMSO)230.00€Suprofen
CAS:Formula:C14H12O3SPurity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:260.31Felbinac
CAS:Felbinac (Dapson), a topical medicine, is an active metabolite of fenbufen. Felbinac is belonging to the family of NSAIDs of the arylpropionic acid class.Formula:C14H12O2Purity:99.47%Color and Shape:Beige Beige PowderMolecular weight:212.24NF157
CAS:NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.Formula:C49H28F2N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1437.1Thioflosulide
CAS:Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.Formula:C16H13F2NO3S2Purity:100%Color and Shape:SolidMolecular weight:369.41Nepafenac
CAS:Nepafenac (AHR 9434) is an NSAID that acts as a cyclooxygenase inhibitor.Formula:C15H14N2O2Purity:98.94% - 99.88%Color and Shape:SolidMolecular weight:254.28Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16Bismuth Subsalicylate
CAS:Bismuth Subsalicylate, Pepto-Bismol's active ingredient, treats nausea, heartburn, indigestion, diarrhea, and stomach upset.Formula:C7H5BiO4Purity:100%Color and Shape:White Solid PowderMolecular weight:362.092-[(2,3-Dimethylphenyl)amino]benzoic acid
CAS:Formula:C15H15NO2Purity:95%Color and Shape:SolidMolecular weight:241.2851Bromfenac sodium hydrate
CAS:Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.Formula:C15H12BrNO3H2O·NaPurity:91.85% - 99.65%Color and Shape:SolidMolecular weight:383.17COX-2-IN-33
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.Formula:C20H13ClF3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.8N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
CAS:Formula:C13H18N2O5SPurity:98%Color and Shape:SolidMolecular weight:314.3574Hexahydrocurcumin
CAS:Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.Formula:C21H26O6Purity:99.43% - 99.77%Color and Shape:SolidMolecular weight:374.43Ref: TM-TQ0288
1mg119.00€5mg283.00€10mg418.00€25mg692.00€50mg938.00€100mg1,320.00€500mg2,642.00€1mL*10mM (DMSO)313.00€Acemetacin
CAS:Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin.Formula:C21H18ClNO6Purity:99.26%Color and Shape:Light Yellow SolidMolecular weight:415.82Deracoxib
CAS:Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.Formula:C17H14F3N3O3SPurity:100% - 99.81%Color and Shape:SolidMolecular weight:397.37Indolo[2,1-b]quinazoline-6,12-dione
CAS:Formula:C15H8N2O2Purity:96%Color and Shape:SolidMolecular weight:248.23624-Biphenylacetic Acid
CAS:Formula:C14H12O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:212.25Clonixin
CAS:Formula:C13H11ClN2O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:262.69Tyrphostin AG 490
CAS:Formula:C17H14N2O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:294.31Insulin levels modulator
CAS:Insulin level regulators can be used to treat diabetes.Formula:C21H23N7OSPurity:98%Color and Shape:SolidMolecular weight:421.52Metyrosine
CAS:Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.Formula:C10H13NO3Purity:98.68%Color and Shape:SolidMolecular weight:195.22
![Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb-webp%2FB5391.webp&w=3840&q=75)
![[8]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5430.webp&w=3840&q=75)
![2-[(2,3-Dimethylphenyl)amino]benzoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0039LC.webp&w=3840&q=75)
![N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0035EW.webp&w=3840&q=75)
![Indolo[2,1-b]quinazoline-6,12-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0010E4.webp&w=3840&q=75)
