Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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3-Methylsalicylic acid
CAS:3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties,which reduces plasma free fatty acid levels.Formula:C8H8O3Purity:97.36%Color and Shape:SolidMolecular weight:152.15Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formula:C20H17FO3SPurity:99.09% - 99.15%Color and Shape:Yellow SolidMolecular weight:356.41Veratric acid
CAS:Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-Formula:C9H10O4Purity:99.44%Color and Shape:SolidMolecular weight:182.17S-(+)-Ketoprofen
CAS:S-(+)-Ketoprofen, an NSAID, blocks cyclo-oxygenase to reduce pain and inflammation. Sold as Keral, Miracox, Enantyum, and Dolmen in various regions.Formula:C16H14O3Purity:99.44%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:254.282-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid
CAS:Formula:C14H12O3SPurity:98%Color and Shape:SolidMolecular weight:260.3083Trometamol
CAS:Controlled ProductTrometamol: treats acidemia, blocks COX1/COX2, inhibits pro-inflammatory prostaglandins.Formula:C4H11NO3Purity:99.05%Color and Shape:White Solid CrystallineMolecular weight:121.14Antioxidant agent-15
CAS:Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.Formula:C19H14O2Purity:98%Color and Shape:SolidMolecular weight:274.31SC-58125
CAS:SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.Formula:C17H12F4N2O2SPurity:99.57%Color and Shape:SolidMolecular weight:384.35Ref: TM-T23333
5mg39.00€10mg64.00€25mg126.00€50mg188.00€100mg319.00€200mg455.00€1mL*10mM (DMSO)58.00€indomethacin farnesil
CAS:Formula:C34H40ClNO4Purity:98%Color and Shape:SolidMolecular weight:562.1387COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41Tyrphostin AG 1478
CAS:Formula:C16H14ClN3O2Purity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:315.76BN-82451 2HCl
CAS:BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.Formula:C18H28Cl2N2OSPurity:98.55% - 99.84%Color and Shape:SolidMolecular weight:391.4Salicylamide
CAS:Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin.Formula:C7H7NO2Purity:99.96%Color and Shape:White Solid CrystallineMolecular weight:137.14Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Formula:C16H14O3Purity:98.35% - 98.46%Color and Shape:White SolidMolecular weight:254.28Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Formula:C21H19NO3SPurity:97.98% - 99.13%Color and Shape:SolidMolecular weight:365.45Ref: TM-T1867
2mg40.00€5mg60.00€10mg87.00€25mg170.00€50mg274.00€100mg439.00€500mg938.00€1mL*10mM (DMSO)66.00€Mavacoxib
CAS:Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.Formula:C16H11F4N3O2SPurity:99.90%Color and Shape:SolidMolecular weight:385.34(αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
CAS:Formula:C14H14O3Purity:98%Color and Shape:SolidMolecular weight:230.25924-Hydroxyantipyrine
CAS:4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.Formula:C11H12N2O2Purity:99.85%Color and Shape:SolidMolecular weight:204.23Timegadine hydrochloride
CAS:Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.Formula:C20H24ClN5SColor and Shape:SolidMolecular weight:401.96Isoorientin
CAS:Isoorientin (Homoorientin) has antioxidant activity.Formula:C21H20O11Purity:98.84% - 99.48%Color and Shape:SolidMolecular weight:448.38Ref: TM-T6S0722
1mg38.00€5mg84.00€10mg119.00€25mg235.00€50mg376.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)92.00€Antipyrine
CAS:Antipyrine, an analgesic/antipyretic, used orally or as ear drops, tests liver enzyme response to diseases/drugs.Formula:C11H12N2OPurity:99.77%Color and Shape:SolidMolecular weight:188.23N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.69%Color and Shape:SolidMolecular weight:177.24Nimesulide
CAS:Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.Formula:C13H12N2O5SPurity:98% - 99.91%Color and Shape:Yellow Needle-Like CrystalsMolecular weight:308.31Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purity:99.57%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:170.12Losartan Carboxaldehyde
CAS:Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.Formula:C22H21ClN6OPurity:99.10%Color and Shape:SolidMolecular weight:420.89Resveratrol
CAS:Formula:C14H12O3Purity:>99.0%(GC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:228.25COX-2-IN-31
COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).Formula:C17H16N6O4SPurity:98%Color and Shape:SolidMolecular weight:400.41(S)-Flurbiprofen
CAS:Esflurbiprofen is an inhibitor of COX-1 and COX-2.Formula:C15H13FO2Purity:99.99%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:244.26(+/-)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID
CAS:Formula:C14H14O3Purity:98%Color and Shape:SolidMolecular weight:230.25915999999998COX-2-IN-1
CAS:COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).Formula:C18H14ClF3N4O2SPurity:100%Color and Shape:SolidMolecular weight:442.84Ref: TM-T10033
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)283.00€Lornoxicam
CAS:Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, andFormula:C13H10ClN3O4S2Purity:99.41% - 99.53%Color and Shape:Crystalline SolidMolecular weight:371.82Tilmacoxib
CAS:Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).Formula:C16H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:338.4Diclofenac Sodium Salt
CAS:Formula:C14H10Cl2NNaO2Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:318.13Iguratimod
CAS:Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).Formula:C17H14N2O6SPurity:99.93%Color and Shape:White PowderMolecular weight:374.37Oxaprozin
CAS:Formula:C18H15NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:293.32Anti-inflammatory agent 56
CAS:Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties byFormula:C21H15F3N4O4SPurity:98%Color and Shape:SolidMolecular weight:476.43Cimicoxib
CAS:Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.Formula:C16H13ClFN3O3SPurity:98.22%Color and Shape:SolidMolecular weight:381.81Ref: TM-T30937
1mg47.00€2mg58.00€5mg84.00€10mg111.00€25mg178.00€50mg269.00€100mg400.00€1mL*10mM (DMSO)92.00€Diflunisal
CAS:Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.Formula:C13H8F2O3Purity:98.92% - 99.42%Color and Shape:SolidMolecular weight:250.2Benzydamine Hydrochloride
CAS:Formula:C19H23N3O·HClPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:345.87Lornoxicam
CAS:Formula:C13H10ClN3O4S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Yellow powder to crystalMolecular weight:371.81Etodolac
CAS:Etodolac (AY-24236), a pyranocarboxylic NSAID, blocks COX-1/2, reducing pain, fever, inflammation, and inhibits platelet aggregation.Formula:C17H21NO3Purity:99.78% - 99.92%Color and Shape:Crystalline SolidMolecular weight:287.35Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purity:99.58% - 99.91%Color and Shape:SolidMolecular weight:298.33Tyrphostin A1
CAS:Formula:C11H8N2OPurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:184.20Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formula:C14H10Cl2KNO2Purity:99.51%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:334.24Diclofenac diethylamine
CAS:Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).Formula:C18H22Cl2N2O2Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:369.29Parecoxib
CAS:Formula:C19H18N2O4SPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:370.42(R)-Naproxen
CAS:(R)-Naproxen: anti-inflammatory with antipyretic and analgesic effects; treats gout, dysmenorrhea, rheumatoid arthritis.Formula:C14H14O3Purity:99% - 99.94%Color and Shape:SolidMolecular weight:230.26
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