Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Olsalazine disodium
CAS:Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.Formula:C14H8N2Na2O6Purity:99.47% - 99.52%Color and Shape:Yellow Crystalline PowderMolecular weight:346.2Zaltoprofen
CAS:Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.Formula:C17H14O3SPurity:99.72%Color and Shape:Off-White To Pale Yellow Crystalline SolidMolecular weight:298.36Sulfinpyrazone
CAS:Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy.Formula:C23H20N2O3SPurity:98.1%Color and Shape:SolidMolecular weight:404.48Flurbiprofen
CAS:Flurbiprofen is an anti-inflammatory, analgesic, antipyretic that reduces bone resorption by inhibiting carbonic anhydrase.Formula:C15H13FO2Purity:99.63% - 99.96%Color and Shape:SolidMolecular weight:244.2609Ketoprofen
CAS:Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects.Formula:C16H14O3Purity:100% - 99.67%Color and Shape:SolidMolecular weight:254.281H-Pyrazole, 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-
CAS:Formula:C17H12ClF3N2OPurity:95%Color and Shape:SolidMolecular weight:352.73822-(3-Trifluoromethylanilino)benzoic Acid
CAS:Formula:C14H10F3NO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Green powder to crystalMolecular weight:281.23Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23Gaultherin
CAS:Gaultherin offers analgesic and anti-inflammatory effects without causing stomach ulcers, releasing salicylate slowly in the intestine.Formula:C19H26O12Purity:99.49% - 99.85%Color and Shape:SolidMolecular weight:446.4Metamizole Sodium Salt
CAS:Formula:C13H16N3NaO4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:333.34BMP-4
CAS:BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.Formula:C52H93N25O13SColor and Shape:SolidMolecular weight:1308.52Seratrodast
CAS:Seratrodast (ABT-001), a TXA2 receptor blocker, treats asthma; first approved in Japan, 1997.Formula:C22H26O4Purity:99.54% - 99.69%Color and Shape:Pale Orange SolidMolecular weight:354.44Ref: TM-T0212
10mg50.00€25mg72.00€50mg93.00€100mg139.00€200mg173.00€500mg283.00€1mL*10mM (DMSO)52.00€2-[2-(2,6-Dichlorophenyl)aminophenyl]ethanoic acid
CAS:Formula:C14H11Cl2NO2Purity:99%Color and Shape:SolidMolecular weight:296.1486Tetrahydroamentoflavone
CAS:Tetrahydroamentoflavone is a potent XO inhibitor (IC50 = 92 nM, Ki = 982 nM) with anti-inflammatory effects.Formula:C30H22O10Purity:98%Color and Shape:SolidMolecular weight:542.49Curcumin (Natural)
CAS:Formula:C21H20O6Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39Etoricoxib-d4
CAS:Etoricoxib-d4 is the 2H-labeled form of Etoricoxib. Etoricoxib is a COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.Formula:C18H11D4ClN2O2SPurity:100%Color and Shape:SolidMolecular weight:362.87Betamethasone Valerate
CAS:Formula:C27H37FO6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:476.59Naproxen sodium
CAS:Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Formula:C14H13NaO3Purity:99.68% - 99.79%Color and Shape:White PowderMolecular weight:252.24COX-2-IN-2
CAS:COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.Formula:C17H12FN3O2SPurity:98.85%Color and Shape:SolidMolecular weight:341.36Ref: TM-T10032
1mg172.00€5mg416.00€10mg667.00€25mg1,330.00€50mg2,118.00€100mg2,812.00€1mL*10mM (DMSO)424.00€Teriflunomide impurity 3
CAS:Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).Formula:C14H11F3N2OPurity:99.62%Color and Shape:SolidMolecular weight:280.25Ref: TM-T9042
10mg50.00€25mg90.00€50mg134.00€100mg212.00€200mg303.00€500mgTo inquire1mL*10mM (DMSO)35.00€Rofecoxib
CAS:Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandinsFormula:C17H14O4SPurity:99.68% - 99.94%Color and Shape:Off-White (Pale Yellow) Crystalline PowderMolecular weight:314.36COX-2-IN-6
CAS:COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.Formula:C20H27NO6SPurity:98.62% - 99.56%Color and Shape:SoildMolecular weight:409.5CAY10404
CAS:CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34Ref: TM-T8656
2mg35.00€5mg52.00€10mg96.00€25mg177.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)58.00€Xanthohumol
CAS:Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-Formula:C21H22O5Purity:98.19% - 99.67%Color and Shape:Orange PowderMolecular weight:354.4Ref: TM-T3342
5mg66.00€10mg99.00€25mg205.00€50mg305.00€100mg459.00€500mg1,026.00€1mL*10mM (DMSO)74.00€Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.73%Color and Shape:White PowderMolecular weight:354.31Regaloside B
CAS:Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitricFormula:C20H26O11Purity:97.34% - 99.4%Color and Shape:SolidMolecular weight:442.41Metamizole sodium hydrate
CAS:Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).Formula:C13H18N3NaO5SPurity:99.69% - ≥98%Color and Shape:White Or Light Yellow Crystalline Powder Odorless Tiny BitterMolecular weight:351.36COX-2-IN-49
COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.Color and Shape:Odour SolidRofecoxib
CAS:Formula:C17H14O4SPurity:>98.0%(GC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:314.36Isoxicam
CAS:Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.Formula:C14H13N3O5SPurity:99.02%Color and Shape:SolidMolecular weight:335.34Sodium Meclofenamate
CAS:Formula:C14H10Cl2NNaO2Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:318.13Amtolmetin guacil
CAS:Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性,具有额外的镇痛、解热和胃保护特性。Formula:C24H24N2O5Purity:99.63%Color and Shape:White Needle-Shaped CrystalMolecular weight:420.46Asaraldehyde
CAS:Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1.Formula:C10H12O4Purity:99.74% - 99.85%Color and Shape:Physical Description Beige Powder (Ntp 1992)Molecular weight:196.22-(2,6-Dichloroanilino)phenylacetic Acid
CAS:Formula:C14H11Cl2NO2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:296.15Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purity:98% - 98.75%Color and Shape:SolidMolecular weight:336.345-Aminosalicylic Acid
CAS:Formula:C7H7NO3Purity:>98.0%(T)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:153.14Tiaprofenic Acid
CAS:Formula:C14H12O3SPurity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:260.31Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Formula:C42H70O12Purity:98% - 98.07%Color and Shape:SolidMolecular weight:767Ref: TM-T6S1487
1mg113.00€5mg265.00€10mg426.00€25mg702.00€50mg938.00€100mg1,320.00€1mL*10mM (DMSO)360.00€Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Formula:C7H5NaO3Purity:99.36% - 99.77%Color and Shape:White Solid AmorphousMolecular weight:160.11Columbin
CAS:Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.Formula:C20H22O6Purity:99.34% - 99.74%Color and Shape:SolidMolecular weight:358.39(±)-Naproxen
CAS:Formula:C14H14O3Purity:>98.0%(GC)(T)Color and Shape:White to Light red to Green powder to crystalMolecular weight:230.26Indometacin Farnesil
CAS:Formula:C34H40ClNO4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange clear liquidMolecular weight:562.15Vedaprofen
CAS:Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.Formula:C19H22O2Purity:98.12% - 99.66%Color and Shape:SolidMolecular weight:282.38Licofelone
CAS:Formula:C23H22ClNO2Purity:>95.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:379.88Etoricoxib
CAS:Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties.Formula:C18H15ClN2O2SPurity:99.68%Color and Shape:Off-White PowderMolecular weight:358.84sphondin
CAS:Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.Formula:C12H8O4Purity:99.71% - ≥95%Color and Shape:SolidMolecular weight:216.19Ref: TM-T5758
1mg111.00€5mg274.00€10mg462.00€25mg740.00€50mg1,017.00€100mg1,359.00€1mL*10mM (DMSO)246.00€Tolmetin
CAS:Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.Formula:C15H15NO3Purity:99.69% - 99.74%Color and Shape:Off-White Crystalline PowerMolecular weight:257.28Ebselen
CAS:Formula:C13H9NOSePurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:274.18Indomethacin
CAS:Indomethacin (Indomethacin) is a inhibitor of COX1 and COX2. Indomethacin is a non-steroidal anti-inflammatory agent. Cost-effective and quality-assured.Formula:C19H16ClNO4Purity:99.27% - 99.76%Color and Shape:Pale-Yellow To Yellow-Tan Crystalline Powder Physical Description Crystals (Ntp 1992)Molecular weight:357.79
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