Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Triflusal
CAS:Triflusal (UR1501) is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative.Formula:C10H7F3O4Purity:99.61%Color and Shape:SolidMolecular weight:248.16Ref: TM-T0705
5mg47.00€10mg70.00€25mg116.00€50mg187.00€100mg311.00€200mg469.00€500mg750.00€1mL*10mM (DMSO)50.00€Curcumin (Synthetic)
CAS:Formula:C21H20O6Purity:>97.0%(T)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39Fenbufen
CAS:Formula:C16H14O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:254.29RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formula:C23H20N6O3Purity:99.04%Color and Shape:SolidMolecular weight:428.44Ketorolac tromethamine salt
CAS:Formula:C19H24N2O6Purity:98%Color and Shape:SolidMolecular weight:376.4037Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purity:98.1% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.094-Nonylphenol polyethoxylate
CAS:4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives.Formula:(C2H4O)nC15H24OPurity:98%Color and Shape:Compounds With N20 Are Pale-Yellow To Off-White Pastes Or Waxes Liquid LiquidMolecular weight:514.69Mefenamic Acid
CAS:Formula:C15H15NO2Purity:>98.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:241.29Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurity:99.34%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19Fenoprofen Calcium Dihydrate
CAS:Formula:C30H30CaO8Purity:97%Color and Shape:SolidMolecular weight:558.6324000000001Indobufen
CAS:Formula:C18H17NO3Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:295.34Deracoxib
CAS:Formula:C17H14F3N3O3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Brown powder to crystalMolecular weight:397.3720(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:100% - 99.93%Color and Shape:SolidMolecular weight:785.01Etofenamate
CAS:Formula:C18H18F3NO4Purity:>98.0%(GC)(T)Color and Shape:Colorless to Yellow clear liquidMolecular weight:369.34Oxyphenbutazone
CAS:Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.Formula:C19H20N2O3Purity:99.41% - 99.88%Color and Shape:White To Yellowish White Crystalline Powder SolidMolecular weight:324.37(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide；AG 490
CAS:Formula:C17H14N2O3Purity:98%Color and Shape:SolidMolecular weight:294.3047SC57666
CAS:SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.Formula:C18H17FO2SPurity:99.48%Color and Shape:SolidMolecular weight:316.39Ref: TM-T12860
1mg116.00€5mg245.00€10mg391.00€25mg667.00€50mg873.00€100mg1,130.00€200mg1,510.00€1mL*10mM (DMSO)269.00€NLRP3-IN-69
CAS:NLRP3-IN-69 (Compound 23) inhibits the activation of NF-κBp65 and the formation of the NLRP3 inflammasome. It suppresses the overexpression of IL-1β, iNOS, and COX-2 induced by LPS, and inhibits the production of NO (IC50=5.66 μM), thereby demonstrating anti-inflammatory activity.Formula:C25H24O7Color and Shape:SolidMolecular weight:436.454Rebamipide mofetil
CAS:Rebamipide mofetil is an orally active prodrug of Rebamipide which is a mucoprotective agent.Formula:C25H26ClN3O5Purity:99.78%Color and Shape:SolidMolecular weight:483.94Ref: TM-T9472
1mg66.00€2mg96.00€5mg144.00€10mg216.00€25mg406.00€50mg607.00€100mg845.00€1mL*10mM (DMSO)159.00€Ketorolac
CAS:Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.Formula:C15H13NO3Purity:99.68%Color and Shape:White Crystalline Or White PowderMolecular weight:255.27Tiaprofenic acid
CAS:Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.Formula:C14H12O3SPurity:99.51%Color and Shape:SolidMolecular weight:260.31Dehydrodiisoeugenol
CAS:Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.Formula:C20H22O4Purity:99.97%Color and Shape:SolidMolecular weight:326.39Progesic dihydrate
CAS:Fenoprofen calcium hydrate (Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).Formula:C30H30CaO8Purity:100%Color and Shape:SolidMolecular weight:558.63Methyl 2,5-Dihydroxycinnamate
CAS:Formula:C10H10O4Purity:>96.0%(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:194.19Etofenamate
CAS:Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.Formula:C18H18F3NO4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:369.33Glafenine
CAS:Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of variousFormula:C19H17ClN2O4Purity:98.49%Color and Shape:SolidMolecular weight:372.8Tenoxicam
CAS:Formula:C13H11N3O4S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:337.37Pamicogrel
CAS:Pamicogrel (KBT3022) is an inhibitor of COX.Formula:C25H24N2O4SPurity:99.83%Color and Shape:SolidMolecular weight:448.53Ref: TM-T15645
2mg35.00€5mg52.00€10mg78.00€25mg140.00€50mg216.00€100mg349.00€200mg515.00€1mL*10mM (DMSO)52.00€Rutaecarpine
CAS:Rutaecarpine (Rhetine) is an inhibitor of COX-2 with IC50 of 0.28 μM.Formula:C18H13N3OPurity:100% - 97.54%Color and Shape:White SolidMolecular weight:287.32Macelignan
CAS:Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.Formula:C20H24O4Purity:100% - 98.01%Color and Shape:SolidMolecular weight:328.4Ginsenoside C-K
CAS:Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.Formula:C36H62O8Purity:98.09% - 99.65%Color and Shape:SolidMolecular weight:622.87Robenacoxib
CAS:Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.Formula:C16H13F4NO2Purity:98.51%Color and Shape:SolidMolecular weight:327.27Ref: TM-T26109
1mg69.00€2mg89.00€5mg149.00€10mg235.00€25mg455.00€50mg723.00€100mg938.00€500mg1,882.00€Acetylsalicylic Acid
CAS:Formula:C9H8O4Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:180.16Parecoxib Sodium
CAS:Formula:C19H17N2NaO4SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:392.40COX-1/2-IN-9
COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.Formula:C30H20IN9O13S2Color and Shape:SolidMolecular weight:905.57Salicin
CAS:Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.Formula:C13H18O7Purity:98.2% - 99.86%Color and Shape:White Crystals Or PowderMolecular weight:286.28Loxoprofen sodium dihydrate
CAS:Formula:C15H21NaO5Purity:98%Color and Shape:SolidMolecular weight:304.314Celecoxib
CAS:Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor.Formula:C17H14F3N3O2SPurity:100% - 99.98%Color and Shape:White PowderMolecular weight:381.37Tazofelone
CAS:Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.Formula:C18H27NO2SPurity:99.46%Color and Shape:SolidMolecular weight:321.48Ref: TM-T22437
1mg81.00€2mg97.00€5mg156.00€10mg226.00€25mg379.00€50mg538.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)170.00€PF-04634817 succinate
CAS:PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.Formula:C29H42F3N5O7Purity:98%Color and Shape:SolidMolecular weight:629.67COX-2-IN-35
COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].Formula:C22H19NO2S2Purity:98%Color and Shape:SolidMolecular weight:393.52Carprofen
CAS:Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Formula:C15H12ClNO2Purity:98.99% - 99.65%Color and Shape:SolidMolecular weight:273.71DICLOFENAC METHYL ESTER
CAS:Formula:C15H13Cl2NO2Purity:97%Color and Shape:SolidMolecular weight:310.17521999999997Loxoprofen
CAS:Formula:C15H18O3Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:246.31Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purity:96.02% - 98%Color and Shape:SolidMolecular weight:330.35Revaprazan hydrochloride
CAS:Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.Formula:C22H24ClFN4Purity:99.62% - 99.91%Color and Shape:SolidMolecular weight:398.9Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg58.00€5mg97.00€10mg160.00€25mg283.00€50mg418.00€100mg615.00€200mg878.00€1mL*10mM (DMSO)111.00€
