BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
Products of "BACE"
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Epiberberine
CAS:1.Formula:C20H18NO4Purity:98.52% - 99.59%Color and Shape:SolidMolecular weight:336.36BACE1-IN-4
CAS:BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.Formula:C21H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.57Lanabecestat
CAS:Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.Formula:C26H28N4OPurity:98.55%Color and Shape:SolidMolecular weight:412.53Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Formula:C19H21NO4Purity:99.22% - 99.22%Color and Shape:SolidMolecular weight:327.37BACE1 Protein, Human, Recombinant
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.Color and Shape:Lyophilized PowderMolecular weight:49 kDa (predicted); 65 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant (His)
BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:49.9 kDa (predicted); 60-65 kDa (reducing condition, due to glycosylation)AM-6494
CAS:AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).Formula:C22H21F2N5O3SPurity:98%Color and Shape:SolidMolecular weight:473.5NB-360
CAS:NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.Formula:C21H19F4N5O2Purity:99.25%Color and Shape:SolidMolecular weight:449.4Ref: TM-T12188
1mg110.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)249.00€Isorubrofusarin-6-O-β-gentiobioside
CAS:Isorubrofusarin-6-O-β-gentiobioside is derived from from Cassia obtusifolia Linn seeds and shows promising inhibitory activity against AChE and BACE1.Formula:C27H32O15Purity:99.69%Color and Shape:SolidMolecular weight:596.53Aloeresin D
CAS:Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).Formula:C29H32O11Purity:98.11% - 99.57%Color and Shape:SolidMolecular weight:556.56Aloenin
CAS:1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.Formula:C19H22O10Purity:99.69%Color and Shape:SolidMolecular weight:410.37Eslicarbazepine Acetate
CAS:Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.Formula:C17H16N2O3Purity:100% - 99.58%Color and Shape:White To Off-White SolidMolecular weight:296.32Ref: TM-T3285
5mg38.00€10mg50.00€25mg92.00€50mg124.00€100mg170.00€200mg268.00€500mg393.00€1mL*10mM (DMSO)55.00€Anti-BACE1 Antibody-PE (8D358)
Anti-BACE1 Antibody-PE (8D358) is a PE-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-PE (8D358) can be used in FCM.Color and Shape:Odour LiquidAnti-BACE1 Antibody (8A762)
Anti-BACE1 Antibody (8A762) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8A762) can be used in ELISA.Color and Shape:Odour LiquidEpiberberine chloride
CAS:Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 inhibitor.Formula:C20H18ClNO4Purity:99.89%Color and Shape:SolidMolecular weight:371.81BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Formula:C18H14F3N5O2Purity:98%Color and Shape:SolidMolecular weight:389.33Sophoflavescenol
CAS:Sophoflavescenol: PDE5 inhibitor (K(i) 0.005 µM), antioxidant, anti-inflammatory, pro-apoptotic, potential antitumor, mild side effects.Formula:C21H20O6Purity:99.65%Color and Shape:SolidMolecular weight:368.38Phytic acid potassium
CAS:Phytic acid potassium (Inositol polyphosphate dipotassium salt) is an endogenous metabolite present in all eukaryotic cellsFormula:C6H16K2O24P6Purity:98% - 99.52%Color and Shape:SolidMolecular weight:736.22
