NMDAR
N-Methyl-D-Aspartate Receptor (NMDAR) inhibitors are compounds that block the activity of NMDARs, a subtype of glutamate receptors that play a critical role in synaptic plasticity, learning, and memory. Overactivation of NMDARs is implicated in excitotoxicity, which can lead to neuronal damage and is associated with conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. NMDAR inhibitors are essential tools for studying excitotoxicity and for developing neuroprotective therapies. At CymitQuimica, we offer a range of NMDAR inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "NMDAR"
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AV-101
CAS:AV-101 (4-Cl-KYN) is a prodrug antagonist at the glycine site of the NMDA receptor with antidepressant activity that reduces dyskinesia.Formula:C10H11ClN2O3Purity:97.84% - 98.27%Color and Shape:SolidMolecular weight:242.66BZAD01
CAS:BZAD01 is a selective NMDA NR1A/2B receptor antagonist.Formula:C16H12F6N2OPurity:99.51% - 99.78%Color and Shape:SolidMolecular weight:362.27Ref: TM-T25196
5mg50.00€10mg84.00€25mg150.00€50mg226.00€100mg375.00€200mg523.00€1mL*10mM (DMSO)71.00€Aptiganel
CAS:Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke.Formula:C20H21N3Purity:98.19% - 98.90%Color and Shape:SolidMolecular weight:303.4Delucemine Hydrochloride
CAS:Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression.Formula:C16H18ClF2NPurity:98.14% - 99.53%Color and Shape:SolidMolecular weight:297.77Mephenesin
CAS:Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.Formula:C10H14O3Purity:99.49%Color and Shape:SolidMolecular weight:182.22ZL006
CAS:ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.Formula:C14H11Cl2NO4Purity:98.29%Color and Shape:SolidMolecular weight:328.15Ref: TM-T17293
5mg50.00€10mg66.00€25mg117.00€50mg180.00€100mg306.00€200mg444.00€1mL*10mM (DMSO)52.00€(-)-Dizocilpine maleate
CAS:(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.Formula:C20H19NO4Purity:99.89%Color and Shape:White SolidMolecular weight:337.37RPR104632
CAS:RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.Formula:C15H11BrCl2N2O4SPurity:99.06%Color and Shape:SolidMolecular weight:466.13Alaproclate
CAS:Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.Formula:C13H18ClNO2Purity:98.51% - 98.64%Color and Shape:SolidMolecular weight:255.74Dizocilpine
CAS:MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.Formula:C16H15NPurity:99.75% - 99.97%Color and Shape:SolidMolecular weight:221.3MDL-29951
CAS:MDL-29951 is a novel glycine antagonist of NMDA receptor activation.Formula:C12H9Cl2NO4Purity:99.07% - 99.49%Color and Shape:SolidMolecular weight:302.11Ref: TM-T1897
1mg50.00€5mg104.00€10mg180.00€25mg325.00€50mg469.00€100mg645.00€200mg868.00€1mL*10mM (DMSO)108.00€Gacyclidine
CAS:Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.Formula:C16H25NSPurity:100% - 99%Color and Shape:SolidMolecular weight:263.44BDBM50597431
CAS:BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.Formula:C27H43F3O2Purity:98.64% - 99.28%Color and Shape:SoildMolecular weight:456.62ALDH3A1-IN-1
CAS:ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.Formula:C13H18N2O3Purity:99.86%Color and Shape:SolidMolecular weight:250.29Ro 25-6981
CAS:Ro 25-6981: potent, selective NMDA receptor blocker (NR2B), IC50: 0.009 μM (NR1C/NR2B), 52 μM (NR1C/NR2A), useful in Parkinson's research.Formula:C22H29NO2Purity:99.44%Color and Shape:SolidMolecular weight:339.47L-Cysteine S-sulfate
CAS:L-Cysteine S-sulfate (S-Sulfo-L-cysteine) is an effective N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist.Formula:C3H7NO5S2Purity:98.92% - 99.92%Color and Shape:SolidMolecular weight:201.22PEAQX
CAS:PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).Formula:C17H17BrN3O5PPurity:100% - ≥98%Color and Shape:SolidMolecular weight:454.21Ref: TM-T4171
1mg34.00€2mg46.00€5mg74.00€10mg125.00€25mg216.00€50mg338.00€100mg470.00€200mg680.00€1mL*10mM (DMSO)97.00€Co 101244 hydrochloride
CAS:Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.Formula:C21H28ClNO3Purity:98.44%Color and Shape:SolidMolecular weight:377.9MRZ 2-514
CAS:MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with KiFormula:C11H6BrN3O3Purity:98.13%Color and Shape:SolidMolecular weight:308.09Ref: TM-T12110
1mg96.00€5mg202.00€10mg329.00€25mg655.00€50mg1,103.00€100mg1,483.00€1mL*10mM (DMSO)224.00€Rapastinel
CAS:Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.Formula:C18H31N5O6Purity:97.18%Color and Shape:SolidMolecular weight:413.47SDZ 220-040 ammonium
SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders.Formula:C16H19Cl2N2O6PPurity:97.31%Color and Shape:SolidMolecular weight:437.21TCN 201
CAS:TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.Formula:C21H17ClFN3O4SPurity:98.50%Color and Shape:SolidMolecular weight:461.89TCN 213
CAS:TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2BFormula:C18H24N4OS2Purity:99.68%Color and Shape:SolidMolecular weight:376.54Neboglamine hydrochloride
CAS:Neboglamine (CR-2249, XY-2401) hydrochloride boosts NMDA receptor, aids schizophrenia research, and is orally active.Formula:C13H25ClN2O3Purity:97.15% - 99.11%Color and Shape:SolidMolecular weight:292.8DL-AP5
CAS:DL-AP5 is the racemic form of a selective N-methyl-D-aspartate (NMDA) receptor antagonist with anticonvulsant effects.Formula:C5H12NO5PPurity:99.33%Color and Shape:White Fine Crystalline PowderMolecular weight:197.13NMDA-IN-1
CAS:NMDA-IN-1 is a potent and NR2B-selective antagonist of NMDA(NMDA Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM).Formula:C20H23ClFN3OPurity:97.01%Color and Shape:SolidMolecular weight:375.87Ref: TM-T12234
1mg71.00€5mg135.00€10mg226.00€25mg371.00€50mg520.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)149.00€L-701252
CAS:L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM.Formula:C13H10ClNO3Purity:98.53%Color and Shape:White Crystalline SolidMolecular weight:263.68Felbamate
CAS:Felbamate (W-554) is an Anti-epileptic Agent.Formula:C11H14N2O4Purity:100% - 99.44%Color and Shape:White Powder SolidMolecular weight:238.24UBP551
CAS:UBP551 is a potent and selective NMDA receptors modulator.Formula:C11H8O4Purity:98.69%Color and Shape:SolidMolecular weight:204.18Ref: TM-T8351
5mg55.00€10mg82.00€25mg126.00€50mg182.00€100mg273.00€200mg409.00€500mg677.00€1mL*10mM (DMSO)64.00€R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Formula:C22H21FN2O3Purity:100%Color and Shape:SolidMolecular weight:380.41CNS-5161 hydrochloride
CAS:CNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel.Formula:C16H19Cl2N3S2Purity:99.53%Color and Shape:SolidMolecular weight:388.385,7-Dichlorokynurenic acid
CAS:5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.Formula:C10H5Cl2NO3Purity:99.56%Color and Shape:SolidMolecular weight:258.06QNZ46
CAS:QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.Formula:C24H17N3O6Purity:99.65%Color and Shape:SolidMolecular weight:443.41UK-240455
CAS:UK-240455: Potent NMDA glycine antagonist with neuroprotection and motor function benefits in Parkinson's.Formula:C11H11Cl2N3O5SPurity:98.34% - 99.83%Color and Shape:SolidMolecular weight:368.19Ref: TM-T13248
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)680.00€Radiprodil
CAS:Radiprodil (RGH-896) is an oral NMDA NR2B antagonist for potential DPNP neuropathic pain treatment.Formula:C21H20FN3O4Purity:99.74%Color and Shape:SolidMolecular weight:397.4Ref: TM-T5385
1mg48.00€2mg65.00€5mg96.00€10mg153.00€25mg240.00€50mg354.00€100mg532.00€1mL*10mM (DMSO)96.00€N20C hydrochloride
CAS:N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.Formula:C17H21ClN2OPurity:98.58%Color and Shape:SolidMolecular weight:304.81D-AP5
CAS:D-AP5 (D-APV) is a NMDA receptor antagonist.Formula:C5H12NO5PPurity:100% - 98.77%Color and Shape:White Fine Crystalline PowderMolecular weight:197.13CGP 37849
CAS:CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.Formula:C6H12NO5PPurity:99.87%Color and Shape:White SolidMolecular weight:209.14Ref: TM-T7720
1mg127.00€5mg283.00€10mg432.00€25mg697.00€50mg938.00€100mg1,293.00€1mL*10mM (DMSO)281.00€Gavestinel sodium
CAS:Gavestinel (GV 150526): potent, selective oral NMDA antagonist; binds glycine site, pKi 8.5; studied for acute ischemic stroke.Formula:C18H11Cl2N2NaO3Purity:99.04%Color and Shape:SolidMolecular weight:397.19Ro 8-4304
CAS:Ro 8-4304 Hydrochloride is an antagonist of NMDA receptor with IC50 of 0.4 μMFormula:C21H23FN2O3Purity:98%Color and Shape:SolidMolecular weight:370.42Dizocilpine Maleate
CAS:Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor with Kd of 37.2 nM in rat brain membranes.Formula:C20H19NO4Purity:99% - 99.96%Color and Shape:White SolidMolecular weight:337.38SDZ 220-040
CAS:SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂,可诱导根系生长的部分无重力模式 。Formula:C16H16Cl2NO6PPurity:99.33%Color and Shape:SolidMolecular weight:420.18L-689560
CAS:L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.Formula:C17H15Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:380.23CIQ
CAS:CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.Formula:C26H26ClNO5Purity:99.50%Color and Shape:SolidMolecular weight:467.94Dalzanemdor
CAS:Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitiveFormula:C27H43F3O2Purity:100% - 98.20%Color and Shape:SolidMolecular weight:456.621-Aminocyclobutanecarboxylic acid
CAS:1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].Formula:C5H9NO2Purity:99.94%Color and Shape:White To Tan Powder Crystals Crystalline Powder And/Or With ChunksMolecular weight:115.13Aptiganel hydrochloride
CAS:Aptiganel hydrochloride(Cerestat) is the salt form of Aptiganel.Aptiganel is a non-competitive NMDA antagonist with neuroprotective effects used in the treatment of stroke and focal cerebral ischemia.Formula:C20H22ClN3Purity:99.89%Color and Shape:SolidMolecular weight:339.86Ref: TM-T38068
1mg38.00€5mg80.00€10mg126.00€25mg267.00€50mg462.00€100mg700.00€200mg995.00€1mL*10mM (DMSO)88.00€Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Formula:C6H11NO2Purity:98.13%Color and Shape:SolidMolecular weight:129.16Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.50% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Flutriafol
CAS:Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonistFormula:C16H13F2N3OPurity:98.75%Color and Shape:SolidMolecular weight:301.29
