NMDAR
N-Methyl-D-Aspartate Receptor (NMDAR) inhibitors are compounds that block the activity of NMDARs, a subtype of glutamate receptors that play a critical role in synaptic plasticity, learning, and memory. Overactivation of NMDARs is implicated in excitotoxicity, which can lead to neuronal damage and is associated with conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. NMDAR inhibitors are essential tools for studying excitotoxicity and for developing neuroprotective therapies. At CymitQuimica, we offer a range of NMDAR inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "NMDAR"
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Dizocilpine Maleate
CAS:Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor with Kd of 37.2 nM in rat brain membranes.Formula:C20H19NO4Purity:99% - 99.96%Color and Shape:White SolidMolecular weight:337.38SDZ 220-040
CAS:SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂,可诱导根系生长的部分无重力模式 。Formula:C16H16Cl2NO6PPurity:99.33%Color and Shape:SolidMolecular weight:420.18L-689560
CAS:L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.Formula:C17H15Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:380.23CIQ
CAS:CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.Formula:C26H26ClNO5Purity:99.50%Color and Shape:SolidMolecular weight:467.94Dalzanemdor
CAS:Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitiveFormula:C27H43F3O2Purity:100% - 98.20%Color and Shape:SolidMolecular weight:456.621-Aminocyclobutanecarboxylic acid
CAS:1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].Formula:C5H9NO2Purity:99.94%Color and Shape:White To Tan Powder Crystals Crystalline Powder And/Or With ChunksMolecular weight:115.13Aptiganel hydrochloride
CAS:Aptiganel hydrochloride(Cerestat) is the salt form of Aptiganel.Aptiganel is a non-competitive NMDA antagonist with neuroprotective effects used in the treatment of stroke and focal cerebral ischemia.Formula:C20H22ClN3Purity:99.89%Color and Shape:SolidMolecular weight:339.86Ref: TM-T38068
1mg38.00€5mg80.00€10mg126.00€25mg267.00€50mg462.00€100mg700.00€200mg995.00€1mL*10mM (DMSO)88.00€Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Formula:C6H11NO2Purity:98.13%Color and Shape:SolidMolecular weight:129.16Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.50% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Flutriafol
CAS:Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonistFormula:C16H13F2N3OPurity:98.75%Color and Shape:SolidMolecular weight:301.29DNQX disodium salt
CAS:DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptorFormula:C8H2N4Na2O6Purity:98.93%Color and Shape:SolidMolecular weight:296.1Ref: TM-T8459
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)170.00€CGP 78608 hydrochloride
CAS:CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).Formula:C11H14BrClN3O5PPurity:98.96% - 99.68%Color and Shape:SolidMolecular weight:414.58Procyclidine hydrochloride
CAS:Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.Formula:C19H30ClNOPurity:99.95%Color and Shape:Crystals From Petroleum Ether White PowderMolecular weight:323.9L-701324
CAS:L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.Formula:C21H14ClNO3Purity:100% - 98.63%Color and Shape:SolidMolecular weight:363.79Ro 25-6981 Maleate
CAS:Ro 25-6981 Maleate is an NMDA receptor antagonist used in the study of neurological disorders such as Parkinson's and epilepsy.Formula:C26H33NO6Purity:99.42%Color and Shape:SolidMolecular weight:455.54Lanicemine dihydrochloride
CAS:Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is an NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.Formula:C13H16Cl2N2Purity:99.43%Color and Shape:SolidMolecular weight:271.19Ref: TM-T60471
2mg35.00€5mg52.00€10mg93.00€25mg170.00€50mg283.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)47.00€TCS 46b
CAS:TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.Formula:C22H23N3OPurity:99% - 99.81%Color and Shape:SolidMolecular weight:345.44GNE-8324
CAS:GNE-8324 is a GluN2A selective positive allosteric modulator that enhances NMDAR-mediated synaptic responses in inhibitory, but not excitatory, neurons.Formula:C18H18FN3OSPurity:98.68% - 99.34%Color and Shape:SolidMolecular weight:343.42Ref: TM-T31981
1mg150.00€5mg359.00€10mg532.00€25mg848.00€50mg1,121.00€100mg1,539.00€200mg2,072.00€1mL*10mM (DMSO)368.00€Rapastinel Trifluoroacetate
CAS:Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.Formula:C20H32F3N5O8Purity:99.01% - 99.77%Color and Shape:SolidMolecular weight:527.49Ref: TM-T5819
1mg39.00€5mg101.00€10mg170.00€25mg305.00€50mg419.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)116.00€Traxoprodil
CAS:Traxoprodil (CP101606) is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).Formula:C20H25NO3Purity:99.89%Color and Shape:SolidMolecular weight:327.42
