p97
p97 inhibitors are compounds that inhibit p97, also known as Valosin-Containing Protein (VCP), an ATPase involved in various cellular processes, including protein degradation, cell cycle regulation, and DNA repair. p97 is a key player in the ubiquitin-proteasome system and its inhibition is of interest in cancer research, neurodegenerative diseases, and other disorders where protein homeostasis is disrupted. At CymitQuimica, we offer p97 inhibitors to support your research in proteostasis, neurobiology, and cancer therapy.
Products of "p97"
Sort by
Found 15 products on this category.
CB-5339
CAS:p97-IN-1 is a potent inhibitor of p97 with an IC 50 <30 nM [1].Formula:C24H24N6OPurity:98.5%Color and Shape:SoildMolecular weight:412.49ML240
CAS:ML240 is a selective, ATP-competitive p97 inhibitor.Formula:C23H20N6OPurity:100% - 99.66%Color and Shape:SolidMolecular weight:396.44Ref: TM-T3535
1mg38.00€5mg81.00€10mg116.00€25mg205.00€50mg329.00€100mg528.00€200mg752.00€1mL*10mM (DMSO)88.00€ML241 hydrochloride
CAS:ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-Formula:C23H25ClN4OPurity:99.91% - 99.96%Color and Shape:SolidMolecular weight:408.92CB-5083
CAS:CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).Formula:C24H23N5O2Purity:100% - 99.92%Color and Shape:SolidMolecular weight:413.47Ref: TM-T6796
1mg46.00€2mg59.00€5mg87.00€10mg137.00€25mg298.00€50mg469.00€100mg687.00€500mg1,444.00€1mL*10mM (DMSO)97.00€NSC799462
NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.Formula:C30H32F2N6O3SColor and Shape:SolidMolecular weight:594.68UP158
CAS:UP158 enhances ATPase activity and stimulates valosin-containing protein (VCP), with an EC50 of 2.57 μM.Formula:C17H17ClN4O2Color and Shape:SolidMolecular weight:344.8UPCDC30766
CAS:UPCDC30766, a potent allosteric inhibitor of p97, exhibits an IC50 of 12 nM and is applicable for colon cancer research [1].Formula:C30H32F2N6O3SPurity:98%Color and Shape:SolidMolecular weight:594.68UP163
CAS:UP163 enhances ATPase activity and activates valosin-containing protein (VCP), with an EC50 of 9.0 μM. It also reduces MG-132-induced TDP-43 aggregation.Formula:C20H15ClN2O5SColor and Shape:SolidMolecular weight:430.86NMS-873
CAS:NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.Formula:C27H28N4O3S2Purity:99.05% - 99.5%Color and Shape:SolidMolecular weight:520.67NSC819701
NSC819701 is a triazole-based inhibitor of p97ATPase. It inhibits the activity of p97ATPase by binding to specific sites on p97.Formula:C30H32F2N8O3SColor and Shape:SolidMolecular weight:622.69UP12
CAS:UP12 enhances ATPase activity by activating valosin-containing protein (VCP), with an EC50 of 2.57 μM.Formula:C23H16ClN3O3SColor and Shape:SolidMolecular weight:449.91ML241
CAS:ML241 is a potent and selective inhibitors of p97 ATPase.Formula:C23H24N4OPurity:98%Color and Shape:SolidMolecular weight:372.46DBEQ
CAS:DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formula:C22H20N4Purity:98.89% - ≥95%Color and Shape:SolidMolecular weight:340.42Ref: TM-T1969
5mg58.00€10mg95.00€25mg180.00€50mg324.00€100mg410.00€200mg607.00€500mg938.00€1mL*10mM (DMSO)59.00€NPD8733
CAS:NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein (VCP)/p97.Formula:C18H15NO4Purity:98.48%Color and Shape:SolidMolecular weight:309.32Ref: TM-T9008
1mg42.00€5mg87.00€10mg125.00€25mg245.00€50mg399.00€100mg645.00€500mg1,311.00€1mL*10mM (DMSO)183.00€MSC1094308
CAS:MSC1094308 is a reversible, non-ATP-competitive inhibitor targeting type II AAA ATPase (VCP/p97) and type I AAA ATPase (VPS4B) and affects protein degradation.Formula:C29H29F3N2Color and Shape:SolidMolecular weight:462.55
