PAI-1
Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.
Products of "PAI-1"
Sort by
Found 14 products on this category.
GW-6604
CAS:GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.Formula:C19H14N4Purity:99.26%Color and Shape:SolidMolecular weight:298.34Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formula:C32H47N5O6SPurity:99.41%Color and Shape:SolidMolecular weight:629.81Ref: TM-T13257
1mg96.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)325.00€Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formula:C24H16F3NO4Purity:99.16% - 99.75%Color and Shape:SolidMolecular weight:439.38Ref: TM-T2030
2mg44.00€5mg65.00€10mg95.00€25mg154.00€50mg259.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)72.00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35ZK824190
CAS:ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.Formula:C22H20F2N2O4Purity:98.84%Color and Shape:SolidMolecular weight:414.4Ref: TM-T13408
1mg259.00€5mg540.00€10mg775.00€25mg1,188.00€50mg1,596.00€100mg2,157.00€1mL*10mM (DMSO)560.00€Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFormula:C39H62N10O15Purity:99.36%Color and Shape:SolidMolecular weight:910.97Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Formula:C32H31N5OPurity:99.02%Color and Shape:SolidMolecular weight:501.62Ref: TM-T25915
1mg64.00€5mg135.00€10mg205.00€25mg454.00€50mg750.00€100mg1,216.00€1mL*10mM (DMSO)149.00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formula:C16H20O6Purity:99.06% - 99.85%Color and Shape:SolidMolecular weight:308.33UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formula:C14H16ClN5O4SPurity:95.81% - 99.26%Color and Shape:SolidMolecular weight:385.83Ref: TM-T3442
1mg52.00€2mg66.00€5mg108.00€10mg180.00€25mg324.00€50mg487.00€100mg705.00€500mg1,473.00€1mL*10mM (DMSO)117.00€TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formula:C24H20N2O6S4Purity:96.91%Color and Shape:SolidMolecular weight:560.69AZ3976
CAS:AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.Formula:C15H19N5O3Purity:98.01%Color and Shape:SolidMolecular weight:317.34TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formula:C28H27ClN3NaO5Purity:99.02% - 99.55%Color and Shape:SolidMolecular weight:543.98Ref: TM-T4255
2mg42.00€5mg65.00€10mg87.00€25mg169.00€50mg245.00€100mg353.00€200mg492.00€1mL*10mM (DMSO)71.00€Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFormula:C28H27NO3Purity:97.51%Color and Shape:SolidMolecular weight:425.52Ref: TM-T29856
1mg57.00€5mg120.00€10mg188.00€25mg432.00€50mg655.00€100mg1,035.00€200mg1,388.00€1mL*10mM (DMSO)139.00€α 2 Antiplasmin
CAS:Alpha 2 Antiplasmin serves as the principal circulating inhibitor of plasmin. This compound plays a crucial role in regulating fibrinolysis within blood vessels.Color and Shape:Solid
