Protease-activated Receptor
Protease-activated Receptor (PAR) inhibitors are compounds that target and inhibit the activity of PARs, a family of G-protein-coupled receptors that are activated by proteolytic cleavage. These receptors play a role in various physiological processes, including coagulation, inflammation, and tissue repair. PAR inhibitors are valuable tools for studying the mechanisms of these processes and their involvement in diseases such as cancer, cardiovascular disorders, and chronic inflammation. At CymitQuimica, we provide PAR inhibitors to aid your research in signal transduction, immune response, and therapeutic discovery.
Products of "Protease-activated Receptor"
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Found 16 products on this category.
SCH79797
CAS:SCH79797 is a potent and specific protease-activated receptor 1 (PAR1) antagonistwith antimicrobial, anticancer, anti-inflammatory, and neuroprotective effects.Formula:C23H25N5Purity:99.80%Color and Shape:SolidMolecular weight:371.48Parmodulin 2
CAS:ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).Formula:C17H17BrN2O2Purity:96.72% - 99.95%Color and Shape:SolidMolecular weight:361.23BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purity:98.36% - 99.11%Color and Shape:SolidMolecular weight:561.63Thrombin Receptor Activator for Peptide
Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.Formula:C32H51F3N8O9Purity:99.88%Color and Shape:SolidMolecular weight:748.79ML-354
CAS:ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].Formula:C16H14N2O3Purity:99.44%Color and Shape:SolidMolecular weight:282.29Vorapaxar sulfate
CAS:Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.Formula:C29H35FN2O8SPurity:99.46% - 99.91%Color and Shape:SolidMolecular weight:590.66Ref: TM-T3098
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg210.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)99.00€I-191
CAS:I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.Formula:C23H26FN5O2Purity:99.80%Color and Shape:SolidMolecular weight:423.48Ref: TM-T7137
1mg89.00€2mg116.00€5mg188.00€10mg284.00€25mg474.00€50mg688.00€100mg938.00€1mL*10mM (DMSO)210.00€AC-264613
CAS:AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.Formula:C19H18BrN3O2Purity:98%Color and Shape:SolidMolecular weight:400.28Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H38FN3O5Purity:98.25% - 98.5%Color and Shape:SolidMolecular weight:527.63PAR-2-IN-1
CAS:PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.Formula:C12H14ClN3O2Purity:99.75%Color and Shape:SolidMolecular weight:267.71Ref: TM-T8917
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg255.00€100mg375.00€200mg530.00€1mL*10mM (DMSO)56.00€PAR650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.Molecular weight:145.5Protease-Activated Receptor-4 diTFA
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonistFormula:C37H48F6N8O11Purity:98.54%Color and Shape:SolidMolecular weight:894.81Ref: TM-T7740
1mg48.00€2mg60.00€5mg86.00€10mg138.00€25mg274.00€50mg411.00€100mg607.00€1mL*10mM (DMSO)170.00€Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54ENMD-1068 HCl
CAS:ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.Formula:C15H29N3O2Purity:95.79%Color and Shape:SolidMolecular weight:283.41AZ3451
CAS:AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).Formula:C30H27BrN4O3Purity:98.12%Color and Shape:SolidMolecular weight:571.46Vorapaxar
CAS:Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).Formula:C29H33FN2O4Purity:98.77% - 99.93%Color and Shape:SolidMolecular weight:492.58Ref: TM-T7013
1mg74.00€5mg145.00€10mg216.00€25mg393.00€50mg587.00€100mg835.00€500mg1,663.00€1mL*10mM (DMSO)160.00€
