Glutaminase
Glutaminase inhibitors are compounds that inhibit glutaminase, an enzyme that catalyzes the conversion of glutamine to glutamate, a critical step in cellular metabolism, especially in cancer cells. Glutaminase plays a key role in providing energy and biosynthetic precursors for rapidly proliferating cells. Inhibitors of glutaminase are important for exploring metabolic dependencies in cancer cells and developing potential therapeutic strategies. At CymitQuimica, we provide glutaminase inhibitors to support your research in cancer metabolism, cellular bioenergetics, and therapeutic discovery.
Products of "Glutaminase"
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Found 16 products on this category.
UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Formula:C25H26N8O2S2Purity:97.44%Color and Shape:SolidMolecular weight:534.66Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Formula:C22H27N5O5Purity:98.01% - 98.37%Color and Shape:SolidMolecular weight:441.48TG2-IN-3h
CAS:TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitorFormula:C21H26N4O4SPurity:99.34% - 99.76%Color and Shape:SolidMolecular weight:430.52Telaglenastat
CAS:Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.Formula:C26H24F3N7O3SPurity:100% - 99.89%Color and Shape:SolidMolecular weight:571.57Ref: TM-T6797
1g1,130.00€2mg38.00€5mg51.00€10mg79.00€25mg126.00€50mg210.00€100mg350.00€500mg825.00€1mL*10mM (DMSO)65.00€BPTES
CAS:BPTES(IC50 of 0.16 μM) is an effective and specific GlutamiN/Ase GLS1 (KGA) inhibitor.Formula:C24H24N6O2S3Purity:95.83% - 99.64%Color and Shape:SolidMolecular weight:524.68Ref: TM-T6791
1mg37.00€2mg52.00€5mg69.00€10mg88.00€25mg150.00€50mg217.00€100mg324.00€200mg472.00€500mg772.00€1mL*10mM (DMSO)88.00€GLS1 Inhibitor-7
GLS1 Inhibitor-7 (compound 4d) serves as a GLS1 antagonist with an IC50 value of 46.7 μM, demonstrating potential applications in anticancer, antiaging, andFormula:C20H17F3N4O3S2Purity:98%Color and Shape:SolidMolecular weight:482.5GK921
CAS:GK921 is a transglutaminase 2 (TGase) inhibitor.Formula:C21H20N4OPurity:97.44% - 99.49%Color and Shape:SolidMolecular weight:344.41BJJF078
CAS:BJJF078, an aminopiperidine, inhibits human/mouse TG2 (IC50: 41/54 nM) and TG1 (IC50: 0.16 μM), may be used in MS studies.Formula:C27H29N3O6SPurity:98.19%Color and Shape:SoildMolecular weight:523.6Glutaminase C-IN-1
CAS:Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.Formula:C27H27BrN2OPurity:99.68% - 99.82%Color and Shape:SolidMolecular weight:475.42Ref: TM-T3964
2mg42.00€5mg60.00€10mg87.00€25mg162.00€50mg273.00€100mg378.00€200mg557.00€1mL*10mM (DMSO)67.00€L-Albizziin
CAS:L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.Formula:C4H9N3O3Purity:99.98%Color and Shape:White PowderMolecular weight:147.13ZED-1227
CAS:ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac DiseasFormula:C26H36N6O6Purity:99.04%Color and Shape:SolidMolecular weight:528.6Glutaminase-IN-3
CAS:Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.Formula:C19H19F3N6O2SPurity:98.51%Color and Shape:SolidMolecular weight:452.45Glutaminase C-IN-2
Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.Formula:C24H23N7O2SPurity:98%Color and Shape:SolidMolecular weight:473.55GLS1 Inhibitor-4
CAS:GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formula:C29H27F3N10O2S2Purity:98%Color and Shape:SolidMolecular weight:668.726-Diazo-5-oxo-L-nor-Leucine
CAS:6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is an antagonist of glutaminases (Ki : 6 μM).Formula:C6H9N3O3Purity:98.04% - 98.93%Color and Shape:SolidMolecular weight:171.15TGase2-IN-1
CAS:TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46
