Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- STAT
- Stem Cells
- TGF-beta/Smad
- Wnt/beta-catenin
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Products of "Stem Cell and Derivatives"
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Stafib-1
CAS:Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.Formula:C26H24N2O11P2Purity:97.18%Color and Shape:SolidMolecular weight:602.42YAP/TAZ-TEAD-IN-2
YAP/TAZ-TEAD-IN-2 (Compound 51) is a YAP/TAZ-TEAD inhibitor that disrupts the interaction between YAP/TAZ and TEAD. It inhibits the transcriptional activity of TEAD with an IC50 of 1.2 nM. Additionally, YAP/TAZ-TEAD-IN-2 suppresses the expression of target genes (Cyr61, CTGF, AXL, and Survivin) and the proliferation of breast cancer cells.Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44JAK3i
CAS:JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.Formula:C18H15FN4O3Purity:98.61% - 99.81%Color and Shape:SolidMolecular weight:354.34PF-06952229
CAS:PF-06952229 is a selective inhibitor of TGFβRI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer.Formula:C23H24ClFN4O3Purity:99.45%Color and Shape:SolidMolecular weight:458.91TEAD-IN-2
CAS:TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.Formula:C16H18BrF3N2OColor and Shape:SolidMolecular weight:391.23Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Formula:C18H16FN3OPurity:97.10% - 98.74%Color and Shape:SolidMolecular weight:309.34Ref: TM-T3080
1mg82.00€2mg106.00€5mg162.00€10mg221.00€25mg449.00€50mg658.00€100mg939.00€500mg1,882.00€1mL*10mM (DMSO)177.00€MRT-83
CAS:MRT-83 is a potent Smo antagonist.Formula:C31H30N4O5Purity:99.92%Color and Shape:SolidMolecular weight:538.59Ref: TM-T12109
2mg46.00€5mg64.00€10mg92.00€25mg183.00€50mg316.00€100mg447.00€200mg628.00€1mL*10mM (DMSO)74.00€Solcitinib
CAS:Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.Formula:C22H23N5O2Purity:99.61% - 99.82%Color and Shape:SolidMolecular weight:389.45Galunisertib
CAS:Galunisertib (LY2157299) is a selective TGF-β receptor type I (TGF-βRI) inhibitor. Galunisertib has antitumor activity. Cost-effective and quality-assured.Formula:C22H19N5OPurity:97.09% - 99.98%Color and Shape:SolidMolecular weight:369.42Ref: TM-T2510
1g692.00€5mg48.00€10mg55.00€25mg88.00€50mg120.00€100mg188.00€200mg284.00€500mg467.00€1mL*10mM (DMSO)50.00€Casein kinase 1δ-IN-4
CAS:"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formula:C16H12N6SPurity:98%Color and Shape:SolidMolecular weight:320.37Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5JAK-IN-29
JAK-IN-29 (Compound 3) is a potent inhibitor of Janus kinases (JAK) [1].Formula:C17H14ClN5O2Purity:98%Color and Shape:SolidMolecular weight:355.78JAK2 Inhibitor V
CAS:JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formula:C23H24N2OPurity:96.69% - 99.15%Color and Shape:SolidMolecular weight:344.45Ref: TM-T3042
2mg39.00€5mg57.00€10mg85.00€25mg157.00€50mg274.00€100mg505.00€500mg1,121.00€1mL*10mM (DMSO)63.00€SB-772077B dihydrochloride
CAS:SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Formula:C15H20Cl2N8O2Purity:98%Color and Shape:SolidMolecular weight:415.28P17 Peptide
CAS:P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formula:C95H139N27O21Color and Shape:SolidMolecular weight:1995.29Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Color and Shape:LiquidSTAT3 HiBiT degrader 1
CAS:STAT3HiBiT degrader 1 is a potent degrader of STAT3HiBiT, exhibiting a DC50 of less than 0.05 μM in A549 cells.Formula:C58H63F4N10O14PSColor and Shape:SolidMolecular weight:1263.21JK184
CAS:JK184 is a potent Hedgehog (Hh) pathway inhibitor.Formula:C19H18N4OSPurity:99.09% - 99.89%Color and Shape:SolidMolecular weight:350.44TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purity:99.4%Color and Shape:SoildMolecular weight:416.47Ref: TM-T77660
1mg42.00€2mg52.00€5mg87.00€10mg127.00€25mg250.00€50mg373.00€100mg547.00€500mg1,159.00€
