Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- STAT
- Stem Cells
- TGF-beta/Smad
- Wnt/beta-catenin
Show 2 more subcategories
Products of "Stem Cell and Derivatives"
Sort by
Kaempferol 3-neohesperidoside
CAS:Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus muscle.Formula:C27H30O15Purity:98.34%Color and Shape:SolidMolecular weight:594.52Ref: TM-TN1819
1mg62.00€5mg127.00€10mg187.00€25mg315.00€50mg472.00€100mg658.00€1mL*10mM (DMSO)166.00€GSK3a-IN-38
CAS:GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.Formula:C18H20N4OPurity:99.75%Color and Shape:SoildMolecular weight:308.38Casein Kinase II Inhibitor IV
CAS:Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.Formula:C24H23N5O3Purity:98.81% - 99.32%Color and Shape:SolidMolecular weight:429.47Ref: TM-T10687
1mg87.00€5mg170.00€10mg259.00€25mg429.00€50mg605.00€100mg815.00€500mg1,624.00€1mL*10mM (DMSO)180.00€SH-4-54
CAS:SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.Formula:C29H27F5N2O5SPurity:98% - 99.12%Color and Shape:SolidMolecular weight:610.59Ref: TM-T6669
1mg50.00€2mg66.00€5mg96.00€10mg160.00€25mg311.00€50mg502.00€100mg730.00€1mL*10mM (DMSO)135.00€AZD-1480
CAS:AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formula:C14H14ClFN8Purity:97.5% - 98.55%Color and Shape:SolidMolecular weight:348.77AS 1892802
CAS:AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formula:C20H19N3O2Purity:98.9%Color and Shape:SolidMolecular weight:333.38Ref: TM-T22037
1mg52.00€5mg97.00€10mg170.00€25mg378.00€50mg560.00€100mg800.00€200mg1,103.00€1mL*10mM (DMSO)120.00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurity:100% - 99.36%Color and Shape:SolidMolecular weight:509.67EMT inhibitor-1
CAS:EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Formula:C12H12Cl2N2O2SPurity:99%Color and Shape:SolidMolecular weight:319.21Ref: TM-T11190
1mg111.00€5mg264.00€10mg424.00€25mg723.00€50mg1,008.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)283.00€JAK-IN-27
CAS:JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nMFormula:C20H21F2N7OPurity:98%Color and Shape:SolidMolecular weight:413.42Emugrobart
Emugrobart is a humanized IgG1κ antibody targeted at GDF8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidSAG dihydrochloride
CAS:SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.Formula:C28H30Cl3N3OSPurity:100%Color and Shape:SoildMolecular weight:562.984-Chloro-2'-bromoacetophenone
CAS:4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).Formula:C8H6BrClOPurity:99.56%Color and Shape:White To Beige SolidMolecular weight:233.49exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-cateninFormula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44Ref: TM-T22775
5mg34.00€10mg52.00€25mg105.00€50mg173.00€100mg279.00€200mg406.00€1mL*10mM (DMSO)44.00€JAK2-IN-11
CAS:JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 of ≤10 nM against JH2 BIND WT/V617F. This compound effectively suppresses tumor growth.Formula:C31H31F3N8O4Color and Shape:SolidMolecular weight:639.64ABC1183
CAS:ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.Formula:C18H14N4OSPurity:98.53%Color and Shape:SolidMolecular weight:334.39Jagged-1 (188-204) TFA(219127-21-6 free base)
Jagged-1 (188-204) TFA, a JAG-1 skin protein fragment, induces epidermal maturation and keratinocyte stratification.Formula:C95H128F3N25O28S3Purity:99.48%Color and Shape:SolidMolecular weight:2221.37Foxy-5 acetate
Foxy-5 acetate: Wnt 5A agonist, inhibits cancer cell migration/invasion, boosts calcium signaling, doesn't activate β-catenin.Formula:C28H46N6O14S2Purity:98%Color and Shape:SolidMolecular weight:754.83TTP 22
CAS:TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Formula:C16H14N2O2S2Purity:97.08% - 97.78%Color and Shape:SolidMolecular weight:330.42Lats-IN-1
CAS:Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formula:C18H14N4OSPurity:97.54% - 99.82%Color and Shape:SolidMolecular weight:334.39Ref: TM-T9053
1mg73.00€5mg145.00€10mg220.00€25mg437.00€50mg567.00€100mg805.00€200mg1,111.00€1mL*10mM (DMSO)161.00€
