Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- STAT
- Stem Cells
- TGF-beta/Smad
- Wnt/beta-catenin
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Products of "Stem Cell and Derivatives"
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Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purity:97.47% - 99.56%Color and Shape:SolidMolecular weight:414.46Ref: TM-T1849
1mg38.00€2mg49.00€5mg81.00€10mg95.00€25mg166.00€50mg259.00€100mg406.00€200mg625.00€1mL*10mM (DMSO)88.00€GSK3-IN-2
CAS:GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.Formula:C17H19N3OSPurity:98.8%Color and Shape:SolidMolecular weight:313.42Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purity:97.64% - 98.59%Color and Shape:SolidMolecular weight:452.51Ref: TM-T6867
2mg48.00€5mg73.00€10mg90.00€25mg166.00€50mg250.00€100mg376.00€500mg895.00€1mL*10mM (DMSO)79.00€Ciliobrevin A
CAS:Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.Formula:C17H9Cl2N3O2Purity:97.10% - 98.54%Color and Shape:SolidMolecular weight:358.18Ref: TM-T3156
2mg42.00€5mg59.00€10mg85.00€25mg168.00€50mg235.00€100mg331.00€200mg492.00€1mL*10mM (DMSO)69.00€GNE-7883
CAS:GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.Formula:C28H29FN6O2Purity:97.61%Color and Shape:SolidMolecular weight:500.57Ref: TM-T78558
1mg116.00€5mg283.00€10mg455.00€25mg747.00€50mg1,026.00€100mg1,444.00€200mg1,882.00€1mL*10mM (DMSO)310.00€Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurity:99.14%Color and Shape:SoildMolecular weight:483.77Ipafricept
CAS:Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Color and Shape:LiquidRuxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurity:98.34% - 99.01%Color and Shape:SolidMolecular weight:466.46JAK2-IN-9
CAS:Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM.Formula:C20H24N6O2SPurity:98%Color and Shape:SolidMolecular weight:412.51YAP-TEAD-IN-2
CAS:YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)Formula:C25H24ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:470.92ROCK-IN-6
CAS:ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1Formula:C19H19N5O8SPurity:98%Color and Shape:SolidMolecular weight:477.45WAY-656935
CAS:WAY-656935 inhibits ROCK.Formula:C20H28ClN3O3SPurity:98.1%Color and Shape:SolidMolecular weight:425.97Amcasertib
CAS:Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.Formula:C31H33N5O2SPurity:100% - 99.31%Color and Shape:SolidMolecular weight:539.69Zelasudil
CAS:Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formula:C22H21F2N7OPurity:99.15%Color and Shape:SolidMolecular weight:437.445Ref: TM-T69665
1mg92.00€5mg180.00€10mg274.00€25mg469.00€50mg653.00€100mg912.00€200mg1,225.00€1mL*10mM (DMSO)188.00€Rho-Kinase-IN-1
CAS:Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formula:C20H24N4SPurity:99.51%Color and Shape:SolidMolecular weight:352.5Ref: TM-T12721
1mg74.00€5mg145.00€10mg215.00€25mg378.00€50mg530.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)111.00€AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purity:98.6% - 99.39%Color and Shape:Yellow SolidMolecular weight:294.3ROCK-IN-2
CAS:ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Formula:C18H13ClF2N6OPurity:97.29%Color and Shape:SolidMolecular weight:402.79Ref: TM-TQ0110
1mg114.00€5mg274.00€10mg439.00€25mg727.00€50mg1,017.00€100mg1,378.00€1mL*10mM (DMSO)373.00€SKL2001
CAS:SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formula:C14H14N4O3Purity:97.46% - 99.5%Color and Shape:SolidMolecular weight:286.29Ref: TM-T6989
5mg40.00€10mg60.00€25mg107.00€50mg185.00€100mg339.00€200mg510.00€500mg797.00€1mL*10mM (DMSO)66.00€RKI-1447
CAS:RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Formula:C16H14N4O2SPurity:98% - 99.73%Color and Shape:SolidMolecular weight:326.37Ref: TM-T1898
5mg51.00€10mg87.00€25mg187.00€50mg311.00€100mg414.00€200mg520.00€500mg840.00€1mL*10mM (DMSO)57.00€
