Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Products of "Wnt/beta-catenin"
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Found 81 products on this category.
BML-284 hydrochloride
CAS:BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.Formula:C19H19ClN4O3Purity:99.80%Color and Shape:SolidMolecular weight:386.84Ref: TM-T8820
1mg35.00€5mg67.00€10mg88.00€25mg150.00€50mg266.00€100mg462.00€200mg648.00€500mg1,017.00€1mL*10mM (DMSO)89.00€Wnt-C59
CAS:Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.Formula:C25H21N3OPurity:99.56% - 99.95%Color and Shape:SolidMolecular weight:379.45TNIK-IN-2
CAS:TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.Formula:C22H19N3O3Purity:98.09%Color and Shape:SolidMolecular weight:373.4Hematein
CAS:Hematein blocks Akt/PKB, Wnt signaling, promotes apoptosis in lung cancer, is a dye from hematoxylin, and inhibits casein kinase II (IC50: 0.74 μM).Formula:C16H12O6Purity:98%Color and Shape:Dark Brown Crystalline PowderMolecular weight:300.26ABC99
CAS:ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formula:C22H21ClN4O5Purity:98.65%Color and Shape:SoildMolecular weight:456.88Ref: TM-T23602
1mg172.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)354.00€Tabituximab
CAS:BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Color and Shape:LiquidMolecular weight:145.5 kDaHLY78
CAS:HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.Formula:C17H17NO2Purity:99.58%Color and Shape:SolidMolecular weight:267.32JW 67
CAS:JW 67 is an inhibitor of canonical Wnt pathway signaling.Formula:C21H18N2O6Purity:97.02%Color and Shape:SolidMolecular weight:394.38Ref: TM-T22884
1mg46.00€2mg59.00€5mg87.00€10mg137.00€25mg273.00€50mg439.00€100mg647.00€1mL*10mM (DMSO)97.00€IWP-3
CAS:IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Formula:C22H17FN4O2S3Purity:98.38%Color and Shape:SolidMolecular weight:484.59Teplinovivint
CAS:Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathyFormula:C25H26N6O2Purity:97.21%Color and Shape:SolidMolecular weight:442.51TNIK-IN-5
CAS:TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formula:C22H17N3O3Purity:99.75%Color and Shape:SolidMolecular weight:371.39FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Ref: TM-T2413
5mg38.00€10mg57.00€25mg94.00€50mg164.00€100mg274.00€200mg404.00€500mg653.00€1mL*10mM (DMSO)64.00€Miclxin
CAS:Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potentFormula:C26H27N5O2Purity:100% - 99.57%Color and Shape:SolidMolecular weight:441.52Ref: TM-T73415
1mg64.00€5mg140.00€10mg192.00€25mg324.00€50mg452.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)156.00€FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formula:C21H16N2O2SPurity:99.37% - 99.89%Color and Shape:SolidMolecular weight:360.43Ref: TM-T24076
1mg42.00€5mg64.00€10mg99.00€25mg188.00€50mg328.00€100mg528.00€500mg1,130.00€1mL*10mM (DMSO)62.00€Toxoflavin
CAS:Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A.Formula:C7H7N5O2Purity:98.24% - 99.7%Color and Shape:SolidMolecular weight:193.16Wnt/β-catenin agonist 3
CAS:Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.Formula:C16H15ClN4O2Purity:99.39%Color and Shape:SolidMolecular weight:330.77Ref: TM-T9988
5mg74.00€10mg107.00€25mg216.00€50mg354.00€100mg567.00€200mg800.00€500mg1,198.00€1mL*10mM (DMSO)81.00€PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.Formula:C33H35N6O7PPurity:98.25% - 99.11%Color and Shape:SoildMolecular weight:658.641(R),2(S)-epoxy Cannabidiol
CAS:1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46Wnt/β-catenin agonist 4
CAS:Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.Formula:C16H15FN4O2Purity:99.61%Color and Shape:SolidMolecular weight:314.31Ref: TM-T60803
1mg35.00€5mg70.00€10mg103.00€25mg182.00€50mg311.00€100mg512.00€200mg720.00€1mL*10mM (DMSO)81.00€IWR-1
CAS:IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).Formula:C25H19N3O3Purity:98.46% - 99.82%Color and Shape:SolidMolecular weight:409.44WIC1
CAS:2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.Formula:C22H23N3O3Purity:99.57%Color and Shape:SoildMolecular weight:377.44F7H
CAS:F7H is an FZD7 antagonist, a potent ligand for the FZD7 transmembrane domain (TMD), with potential antitumor and bacteriostatic activities.Formula:C24H18FN3O2S2Purity:99.85%Color and Shape:SoildMolecular weight:463.55NRX-103094
CAS:NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.Formula:C20H11Cl2F3N2O4SPurity:99.50%Color and Shape:SolidMolecular weight:503.28Gossypolone
CAS:Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.Formula:C30H26O10Purity:96.66%Color and Shape:SolidMolecular weight:546.52TNKS-2-IN-2
CAS:TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.Formula:C26H23N3O6Purity:99.45%Color and Shape:SoildMolecular weight:473.48KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Formula:C17H11N2O6S2·KPurity:97.57% - 99.33%Color and Shape:SolidMolecular weight:442.51N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
CAS:Macamide Impurity 14 promotes bone growth by activating Wnt/β-catenin, aiding osteoporosis study.Formula:C26H39NO2Purity:98.66%Color and Shape:SolidMolecular weight:397.59TNIK-IN-3
CAS:TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formula:C23H18FN3O2Purity:99.56%Color and Shape:SolidMolecular weight:387.41Ref: TM-T9556
1mg106.00€5mg259.00€10mg406.00€25mg652.00€50mg938.00€100mg1,454.00€1mL*10mM (DMSO)284.00€ZW4864 free base
CAS:ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.Formula:C33H42N6O3Purity:99.54%Color and Shape:SolidMolecular weight:570.72Ref: TM-T9642
1mg160.00€5mg393.00€10mg587.00€25mg935.00€50mg1,264.00€100mg1,700.00€500mg3,410.00€1mL*10mM (DMSO)432.00€iCRT 14
CAS:iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).Formula:C21H17N3O2SPurity:98.85% - 99.8%Color and Shape:SolidMolecular weight:375.44IQ 1
CAS:IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:SolidMolecular weight:362.42Ref: TM-T3635
5mg51.00€10mg78.00€25mg140.00€50mg195.00€100mg350.00€200mg500.00€500mg810.00€1mL*10mM (DMSO)57.00€CDK8-IN-11
CAS:CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.Formula:C19H15F3N4O2Purity:99.74%Color and Shape:SolidMolecular weight:388.34Ref: TM-T61742
1mg59.00€5mg127.00€10mg205.00€25mg454.00€50mg748.00€100mg1,054.00€200mg1,415.00€1mL*10mM (DMSO)139.00€YW2036
CAS:YW2036 is an inhibitor of Wnt signaling pathway.Formula:C20H16N4OPurity:100%Color and Shape:SoildMolecular weight:328.37LF3
CAS:LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formula:C20H24N4O2S2Purity:99.63%Color and Shape:SolidMolecular weight:416.56SRI 37892
CAS:SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.Formula:C26H19N5O2SPurity:98.92%Color and Shape:SolidMolecular weight:465.53Ref: TM-T9662
1mg378.00€5mg922.00€10mg1,225.00€25mg1,853.00€50mg2,490.00€100mg3,353.00€1mL*10mM (DMSO)1,074.00€FzM1.8
CAS:FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.Formula:C18H14N2O4Purity:100%Color and Shape:SolidMolecular weight:322.31Ref: TM-T15363
2mg42.00€5mg60.00€10mg96.00€25mg177.00€50mg283.00€100mg454.00€200mg653.00€1mL*10mM (DMSO)95.00€Neurodazine
CAS:Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Formula:C27H21ClN2O3Purity:98.01%Color and Shape:SolidMolecular weight:456.92Carboxylesterase-IN-3
CAS:Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.Formula:C11H6Cl2N4OSPurity:97.49% - 97.89%Color and Shape:SolidMolecular weight:313.16Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purity:99.4%Color and Shape:SoildMolecular weight:416.47Ref: TM-T77660
1mg42.00€2mg52.00€5mg87.00€10mg127.00€25mg250.00€50mg373.00€100mg547.00€500mg1,159.00€Pyrvinium pamoate
CAS:Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drugFormula:C26H28N3C23H14O6Purity:100% - 98.43%Color and Shape:SolidMolecular weight:575.71β-catenin-IN-2
CAS:β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formula:C15H14FN3Purity:98.78%Color and Shape:SolidMolecular weight:255.29Ref: TM-T9696
1mg96.00€5mg227.00€10mg359.00€25mg607.00€50mg868.00€100mg1,169.00€500mg2,365.00€1mL*10mM (DMSO)264.00€KY02111
CAS:KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.Formula:C18H17ClN2O3SPurity:97.71%（96.56%） - 98.68%Color and Shape:SolidMolecular weight:376.86Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurity:96.13%Color and Shape:SolidMolecular weight:717.63Cardiogenol C
CAS:Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.Formula:C13H16N4O2Purity:98.46%Color and Shape:SolidMolecular weight:260.29EMT inhibitor-1
CAS:EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Formula:C12H12Cl2N2O2SPurity:99%Color and Shape:SolidMolecular weight:319.21Ref: TM-T11190
1mg111.00€5mg264.00€10mg424.00€25mg723.00€50mg1,008.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)283.00€exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-cateninFormula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44Ref: TM-T22775
5mg34.00€10mg52.00€25mg105.00€50mg173.00€100mg279.00€200mg406.00€1mL*10mM (DMSO)44.00€Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Color and Shape:Liquidβ-catenin/CBP-IN-1
CAS:β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFormula:C33H35N6O7PPurity:98%Color and Shape:SolidMolecular weight:658.64Ipafricept
CAS:Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Color and Shape:LiquidSKL2001
CAS:SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formula:C14H14N4O3Purity:97.46% - 99.5%Color and Shape:SolidMolecular weight:286.29Ref: TM-T6989
5mg40.00€10mg60.00€25mg107.00€50mg185.00€100mg339.00€200mg510.00€500mg797.00€1mL*10mM (DMSO)66.00€KY1220
CAS:KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formula:C14H10N4O3SPurity:99.66%Color and Shape:SolidMolecular weight:314.32Ref: TM-T15677
2mg46.00€5mg80.00€10mg117.00€25mg259.00€50mg374.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)73.00€NRX-252262
CAS:NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)Formula:C23H17Cl2F3N2O4SPurity:99.10% - 99.87%Color and Shape:SolidMolecular weight:545.36Ref: TM-T9182
1mg114.00€5mg273.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)329.00€MSAB
CAS:MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Formula:C15H15NO4SPurity:99.76%Color and Shape:SolidMolecular weight:305.35Ref: TM-T8710
1mg37.00€2mg49.00€5mg73.00€10mg119.00€25mg235.00€50mg354.00€100mg535.00€500mg1,121.00€1mL*10mM (DMSO)82.00€LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.Formula:C11H9ClN2O2S2Purity:99.91%Color and Shape:SolidMolecular weight:300.78DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurity:98.15%Color and Shape:SolidMolecular weight:407.7NRX-252114
CAS:NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formula:C22H12Cl2F3N3O2SPurity:98.26%Color and Shape:SolidMolecular weight:510.32Dendrobium phenol
CAS:Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.Formula:C16H18O4Purity:98.66% - 99.48%Color and Shape:SolidMolecular weight:274.31Ref: TM-TL0008
1mg49.00€2mg65.00€5mg97.00€10mg156.00€25mg255.00€50mg373.00€100mg555.00€1mL*10mM (DMSO)165.00€Pamidronic acid
CAS:Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem CellsFormula:C3H11NO7P2Purity:97.72%Color and Shape:SolidMolecular weight:235.07Wnt pathway activator 2
CAS:Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formula:C17H15NO4Purity:98.28%Color and Shape:SolidMolecular weight:297.31Ref: TM-T13345
1mg49.00€5mg105.00€10mg169.00€25mg344.00€50mg562.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)116.00€JW74
CAS:JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formula:C24H20N6O2SPurity:95.00%Color and Shape:SolidMolecular weight:456.52BML-284
CAS:BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formula:C19H18N4O3Purity:99.66% - 99.91%Color and Shape:SolidMolecular weight:350.37Ref: TM-T3144
5mg60.00€10mg88.00€25mg140.00€50mg253.00€100mg427.00€200mg615.00€500mg938.00€1mL*10mM (DMSO)66.00€WAY-262611
CAS:WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Formula:C20H22N4Purity:98.09% - 99.09%Color and Shape:SolidMolecular weight:318.42Adavivint
CAS:Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.Formula:C29H24FN7OPurity:98.27% - 98.6%Color and Shape:SolidMolecular weight:505.55CCT 031374 hydrobromide
CAS:CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formula:C23H20BrN3OPurity:98.61%Color and Shape:SolidMolecular weight:434.33Ref: TM-T21685
1mg38.00€5mg71.00€10mg105.00€25mg207.00€50mg329.00€100mg472.00€200mg620.00€1mL*10mM (DMSO)87.00€IWP-4
CAS:IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.Formula:C23H20N4O3S3Purity:100.00%Color and Shape:SolidMolecular weight:496.62Cardiogenol C hydrochloride
CAS:Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).Formula:C13H17ClN4O2Purity:99.89% - 99.94%Color and Shape:SolidMolecular weight:296.75TNIK-IN-7
CAS:TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cellsFormula:C23H22N4O2Purity:99.87%Color and Shape:SoildMolecular weight:386.45Tankyrase-IN-2
CAS:Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormula:C17H14F2N2O2Purity:98%Color and Shape:SolidMolecular weight:316.3BML-286
CAS:BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formula:C22H18N2O4Color and Shape:SolidMolecular weight:374.39Carboxylesterase-IN-2
CAS:Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.Formula:C13H12N4OSPurity:100%Color and Shape:SoildMolecular weight:272.33Ref: TM-T77524
1mg62.00€5mg140.00€10mg215.00€25mg369.00€50mg509.00€100mg702.00€200mg944.00€1mL*10mM (DMSO)156.00€IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formula:C26H20N6OPurity:99.12%Color and Shape:SolidMolecular weight:432.48Ref: TM-T5342
2mg39.00€5mg64.00€10mg101.00€25mg163.00€50mg226.00€100mg320.00€200mg459.00€1mL*10mM (DMSO)70.00€Wnt pathway inhibitor 3
CAS:Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studiesFormula:C21H17BrN2O5Purity:99.69%Color and Shape:SoildMolecular weight:457.27NRX-103095
CAS:NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.Formula:C22H16Cl2F3N3O3SPurity:99.16% - 99.60%Color and Shape:SolidMolecular weight:530.35Ref: TM-T63730
1mg150.00€5mg364.00€10mg588.00€25mg1,169.00€50mg1,882.00€100mg2,822.00€1mL*10mM (DMSO)426.00€KY-05009
CAS:KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).Formula:C18H16N4O2SPurity:98.06%Color and Shape:SolidMolecular weight:352.41Ref: TM-T11793
5mg50.00€10mg71.00€25mg117.00€50mg170.00€100mg245.00€200mg354.00€1mL*10mM (DMSO)51.00€CCT251545
CAS:CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).Formula:C23H24ClN5OPurity:98.2% - 98.69%Color and Shape:SolidMolecular weight:421.92β-catenin modulator IIa-661
CAS:β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.Formula:C19H23ClN2O3SPurity:99.53%Color and Shape:SoildMolecular weight:394.92ETC-159
CAS:ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.Formula:C19H17N7O3Purity:96.87% - 99.30%Color and Shape:SolidMolecular weight:391.38Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Formula:C18H16O4Purity:99.94%Color and Shape:SolidMolecular weight:296.32Ref: TM-T17256
2mg34.00€5mg52.00€10mg80.00€25mg131.00€50mg212.00€100mg316.00€200mg454.00€1mL*10mM (DMSO)52.00€Blosozumab
CAS:Blosozumab (LY2541546) is a monoclonal antibody targeting sclerostin that promotes bone formation, used in the research of osteoporosis.Purity:>95% - >95%Color and Shape:Liquid
