Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Products of "Stem Cells"
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JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formula:C26H32FN9O2Purity:98%Color and Shape:SolidMolecular weight:521.59Cyclopamine
CAS:Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.Formula:C27H41NO2Purity:98.31% - 99.66%Color and Shape:White Crystalline SolidMolecular weight:411.62BRD0209
CAS:BRD0209 is a highly selective and potent GSK3 inhibitor.Formula:C22H25N3OPurity:99.75%Color and Shape:SolidMolecular weight:347.45Casein kinase 1δ-IN-4
CAS:"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formula:C16H12N6SPurity:98%Color and Shape:SolidMolecular weight:320.37JAK2 Inhibitor V
CAS:JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formula:C23H24N2OPurity:96.69% - 99.15%Color and Shape:SolidMolecular weight:344.45Ref: TM-T3042
2mg39.00€5mg57.00€10mg85.00€25mg157.00€50mg274.00€100mg505.00€500mg1,121.00€1mL*10mM (DMSO)63.00€5β-Cholanic acid
CAS:5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.Formula:C24H40O2Purity:99.89%Color and Shape:SoildMolecular weight:360.57SB-772077B dihydrochloride
CAS:SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Formula:C15H20Cl2N8O2Purity:98%Color and Shape:SolidMolecular weight:415.28P17 Peptide
CAS:P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formula:C95H139N27O21Color and Shape:SolidMolecular weight:1995.29Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Color and Shape:LiquidDemcizumab
CAS:Demcizumab (OMP 21M18), an anti-DLL4 antibody, inhibits the Notch pathway and fights various cancers solo or with chemo.Purity:> 95%Color and Shape:LiquidMolecular weight:145.34 kDaDPP
CAS:DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstratingFormula:C36H40Cl2N2O10PtPurity:98%Color and Shape:SolidMolecular weight:926.7BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Color and Shape:SolidMolecular weight:518.5Enoticumab
CAS:Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits cancer cell growth.Color and Shape:LiquidAJI-100
CAS:AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).Formula:C17H14FN5OColor and Shape:SolidMolecular weight:323.32TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formula:C27H25F3N4O4Purity:≥98%Color and Shape:SolidMolecular weight:526.51CSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formula:C25H30FN9OColor and Shape:SolidMolecular weight:491.56Casein kinase 1δ-IN-3
CAS:Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.Formula:C17H16N2O2SPurity:99.42%Color and Shape:SoildMolecular weight:312.39Ref: TM-T64350
1mg38.00€5mg73.00€10mg115.00€25mg235.00€50mg373.00€100mg560.00€200mg797.00€1mL*10mM (DMSO)87.00€H-1152 dihydrochloride
CAS:H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.Formula:C16H23Cl2N3O2SPurity:98.42%Color and Shape:SolidMolecular weight:392.34Ref: TM-T35328
1mg64.00€5mg142.00€10mg227.00€25mg439.00€50mg692.00€100mg938.00€1mL*10mM (DMSO)156.00€MSC-5046
MSC-5046 is a selective inhibitor of TEAD1.Formula:C24H18F3N5O3Color and Shape:SolidMolecular weight:481.43WAY-297174
CAS:WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.Formula:C11H12N2O2S2Purity:99.43%Color and Shape:SoildMolecular weight:268.36Ref: TM-T60067
1mg84.00€5mg163.00€10mg229.00€25mg379.00€50mg568.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)155.00€
