Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Products of "Stem Cells"
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WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.Formula:C16H14Br2ClN3O3Purity:99.49%Color and Shape:SolidMolecular weight:491.56Verosudil
CAS:Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.Formula:C17H17N3O2SPurity:99.72%Color and Shape:SolidMolecular weight:327.4Ref: TM-T60924
1mg87.00€5mg250.00€10mg406.00€25mg652.00€50mg919.00€100mg1,216.00€1mL*10mM (DMSO)274.00€SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H32ClN3OPurity:98.24% - 99.59%Color and Shape:SolidMolecular weight:365.94Ref: TM-T5129
2mg47.00€5mg70.00€10mg111.00€25mg227.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)77.00€YAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP-TEAD interaction with an IC50 of 25 nM.Formula:C95H148ClN23O23S2Purity:98.11% - 99.57%Color and Shape:SoildMolecular weight:2079.92CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ref: TM-T7764
2mg42.00€5mg65.00€10mg99.00€25mg182.00€50mg279.00€100mg414.00€200mg587.00€1mL*10mM (DMSO)70.00€Rovalpituzumab
CAS:Rovalpituzumab: humanized antibody against DLL3, forms ADCs, treats small cell lung cancer.Purity:> 95%Color and Shape:LiquidMolecular weight:145.02 kDa3,7-DMF
CAS:3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.Formula:C17H14O4Purity:98%Color and Shape:SolidMolecular weight:282.29Narciclasine
CAS:Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.Formula:C14H13NO7Purity:98.79% - 99.58%Color and Shape:SolidMolecular weight:307.26CX-5011
CAS:CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].Formula:C20H12N4O2Purity:98%Color and Shape:SolidMolecular weight:340.33Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8Ref: TM-T7885
2mg52.00€5mg74.00€10mg95.00€25mg163.00€50mg253.00€100mg437.00€200mg568.00€1mL*10mM (DMSO)86.00€TGFβ1-IN-1
CAS:TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.Formula:C22H24N2O3Purity:99.89%Color and Shape:SolidMolecular weight:364.438Taladegib
CAS:Taladegib (LY2940680), an oral Smo receptor antagonist, targets Hedgehog signaling for cancer treatment.Formula:C26H24F4N6OPurity:100% - 99.39%Color and Shape:SolidMolecular weight:512.5GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurity:98.86%Color and Shape:SolidMolecular weight:337.36Ref: TM-T8605
1mg131.00€2mg188.00€5mg283.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€1mL*10mM (DMSO)298.00€Vismodegib
CAS:Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).Formula:C19H14Cl2N2O3SPurity:98% - 99.99%Color and Shape:SolidMolecular weight:421.3URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purity:98.43% - 99.32%Color and Shape:SolidMolecular weight:421.54KY19382
CAS:KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.Formula:C17H11Cl2N3O2Purity:98.06%Color and Shape:SolidMolecular weight:360.19Ref: TM-T9025
1mg99.00€5mg197.00€10mg350.00€25mg590.00€50mg840.00€100mg1,130.00€500mg2,308.00€1mL*10mM (DMSO)243.00€Nisevokitug
CAS:Nisevokitug (NIS-793) is an IgG2λ human monoclonal antibody that targets TGF-β (TGFB1/TGFB2). It is produced in CHO-K1 cells [1].Purity:98%Color and Shape:LiquidAβ42-IN-2
CAS:Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].Formula:C24H26N6O2Purity:100% - 99.49%Color and Shape:SolidMolecular weight:430.5Ref: TM-T9641
1mg42.00€5mg94.00€10mg134.00€25mg215.00€50mg304.00€100mg420.00€200mg582.00€1mL*10mM (DMSO)93.00€(R)-Lisofylline
CAS:(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM).Formula:C13H20N4O3Purity:99.50%Color and Shape:SolidMolecular weight:280.32BMS-906024
CAS:BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.Formula:C26H26F6N4O3Purity:100% - 99.87%Color and Shape:SolidMolecular weight:556.5GSK3β inhibitor II
CAS:GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).Formula:C14H10IN3OSPurity:99.32%Color and Shape:SolidMolecular weight:395.22TNKS-2-IN-2
CAS:TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.Formula:C26H23N3O6Purity:99.45%Color and Shape:SoildMolecular weight:473.48CRT0066854 hydrochloride
CAS:CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Formula:C24H27Cl2N5SPurity:97.51%Color and Shape:SolidMolecular weight:488.48STAT3-IN-B9
CAS:STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.Formula:C20H13NO5SPurity:98.16%Color and Shape:SolidMolecular weight:379.39Ref: TM-T28865
1mg115.00€2mg162.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)269.00€GANT 58
CAS:GANT 58 (NSC-75503) is a potent antagonist of Gli. Which inhibits GLI1-induced transcription (IC50: 5 μM).Formula:C24H16N4SPurity:99.53%Color and Shape:SolidMolecular weight:392.48KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Formula:C17H11N2O6S2·KPurity:97.57% - 99.33%Color and Shape:SolidMolecular weight:442.51Casein kinase 1δ-IN-1
CAS:Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.Formula:C11H7N3OSPurity:99.46%Color and Shape:SolidMolecular weight:229.26STAT3-IN-37
CAS:STAT3-IN-37 (Compound 101) is an inhibitor of STAT3, with an IC50 of 15 nM as measured by DNA-HTRF assay and 2 nM as determined through human whole blood SOCS3 qPCR assay.Formula:C23H25Cl2N5O2Color and Shape:SolidMolecular weight:474.38N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
CAS:Macamide Impurity 14 promotes bone growth by activating Wnt/β-catenin, aiding osteoporosis study.Formula:C26H39NO2Purity:98.66%Color and Shape:SolidMolecular weight:397.59Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formula:C25H31N9O2Purity:100% - 98.87%Color and Shape:SolidMolecular weight:489.57Ref: TM-T10431
2mg96.00€5mg163.00€10mg268.00€25mg465.00€50mg618.00€100mg880.00€1mL*10mM (DMSO)170.00€TT-10
CAS:TT-10 (TAZ-K) activates YAP-TEAD; useful in heart disease with cardiomyocyte loss research.Formula:C11H10FN3OS2Purity:99.29%Color and Shape:SolidMolecular weight:283.35γ-secretase modulator 3
CAS:Gamma-secretase modulator 3 (γ-secretase modulator 3) is a γ-secretase modulator that reduces Aβ production.Formula:C24H23FN4OSPurity:98%Color and Shape:SolidMolecular weight:434.53Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€GSK269962A hydrochloride
CAS:GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.Formula:C29H31ClN8O5Color and Shape:SolidMolecular weight:607.06JAK2-IN-4
CAS:JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.Formula:C23H27N5O4SPurity:98%Color and Shape:SolidMolecular weight:469.56C-Peptide 1 (rat)
CAS:C-Peptide 1 (rat), a β-catenin/GSK-3β activator and regulator of the Wnt/β-catenin signaling pathway, is utilized in cancer research [1].Formula:C140H228N38O51Purity:98%Color and Shape:SolidMolecular weight:3259.58HC-258
CAS:HC-258 is a direct TEAD inhibitor covalent Cys380, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 MDA-MB-231.Formula:C20H24N2O2Color and Shape:SolidMolecular weight:324.42STAT3-IN-8
CAS:"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."Formula:C19H7F7N2O3Purity:98%Color and Shape:SolidMolecular weight:444.26ROCK2-IN-7
CAS:ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.Formula:C26H28FN5OPurity:98%Color and Shape:SolidMolecular weight:445.53Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formula:C19H11ClN3NaO2Purity:99.49% - 99.62%Color and Shape:SolidMolecular weight:371.75JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02Ac-GpYLPQTV-NH2 acetate
Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. It also exhibits antitumor properties.Formula:C38H60N9O14P·xC2H4O2Color and Shape:SolidMolecular weight:897.91 (free base)WHN-88
CAS:WHN-88, a Porcupine (PORCN) inhibitor, disrupts the palmitoylation of Wnt ligands, which inhibits their secretion and subsequent Wnt/β-catenin signaling. This compound has shown efficacy in reducing cancer cell stemness and suppressing the progression and development of breast tumors in MMTV-Wnt1 transgenic mice.Formula:C18H13I2N3O2Color and Shape:SolidMolecular weight:557.12TNIK-IN-3
CAS:TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formula:C23H18FN3O2Purity:99.56%Color and Shape:SolidMolecular weight:387.41Ref: TM-T9556
1mg106.00€5mg259.00€10mg406.00€25mg652.00€50mg938.00€100mg1,454.00€1mL*10mM (DMSO)284.00€Sotatercept
CAS:Sotatercept (ACE-011) is an ActRIIA-Fc fusion protein and an inhibitor of activin signaling.Color and Shape:Liquid(+)-ITD-1
CAS:(+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).Formula:C27H29NO3Color and Shape:SolidMolecular weight:415.52Golotimod (TFA) (229305-39-9 free base)
Golotimod (TFA), an immunomodulating peptide, boosts antituberculosis treatments and enhances immune cell growth and macrophage function.Formula:C18H20F3N3O7Purity:98%Color and Shape:SolidMolecular weight:447.36Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formula:C15H19N5OPurity:98.82% - 99.92%Color and Shape:SolidMolecular weight:285.34Ref: TM-T5382
2mg47.00€5mg70.00€10mg111.00€25mg216.00€50mg329.00€100mg495.00€200mg705.00€500mg1,064.00€1mL*10mM (DMSO)77.00€TDZD-8
CAS:TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.Formula:C10H10N2O2SPurity:97.13% - 99.48%Color and Shape:White SolidMolecular weight:222.26MRT-14
CAS:MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.Formula:C24H24N4O5Purity:98.55%Color and Shape:SolidMolecular weight:448.47Ref: TM-T9531
2mg35.00€5mg52.00€10mg85.00€25mg138.00€50mg220.00€100mg329.00€200mg469.00€1mL*10mM (DMSO)65.00€
