Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK
- c-Fms
- c-Kit
- c-Met/HGFR
- c-RET
- CSF-1R
- EGFR
- Ephrin Receptor
- Fibroblast Growth Factor Receptor (FGFR)
- FLT
- Hck
- HER
- IGF-1R
- PDGFR
- PYK2
- Src
- TAM Receptor
- Tie-2
- Trk receptor
- Tyrosine Kinases
- VEGFR
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Products of "Tyrosine Kinase/Adaptors"
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Sorafenib Tosylate
CAS:Formula:C21H16ClF3N4O3·C7H8O3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:637.03CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Formula:C26H24N6OPurity:98%Color and Shape:SolidMolecular weight:436.51Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormula:C24H27ClFN5O3Purity:99.52%Color and Shape:SolidMolecular weight:487.96Ref: TM-T19965
5mg50.00€10mg80.00€25mg105.00€50mg140.00€100mg212.00€200mg311.00€1mL*10mM (DMSO)60.00€(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurity:98.68%Color and Shape:SolidMolecular weight:386.45Ref: TM-T10626
1mg48.00€5mg93.00€10mg135.00€25mg235.00€50mg344.00€100mg487.00€200mg692.00€1mL*10mM (DMSO)97.00€LDN-214117
CAS:LDN-214117 is a potent and selective ALK2 inhibitor.Formula:C25H29N3O3Purity:100% - 99.85%Color and Shape:SolidMolecular weight:419.52Rociletinib
CAS:Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplasticFormula:C27H28F3N7O3Purity:98.39% - 99.25%Color and Shape:SolidMolecular weight:555.55FGFR4-IN-8
CAS:FGFR4-IN-8 is a selective, ATP-competitive FGFR4 inhibitor with IC50s as low as 0.25 nM, halting growth of Hep3B cells at 29 nM and showing in vivo efficacy.Formula:C32H34Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:654.56Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purity:98.66%Color and Shape:SolidMolecular weight:509.344-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-
CAS:Formula:C16H14ClN3O2Purity:99%Color and Shape:SolidMolecular weight:315.75426000000004Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Formula:C11H8N2OPurity:98%Color and Shape:SolidMolecular weight:184.194Heparan Sulfate
CAS:Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG). Cost effective and quality assured.Formula:C12H19NO20S3(monomer)Purity:98%Color and Shape:SolidMolecular weight:593.47(monomer)Ensartinib hydrochloride
CAS:Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of knownFormula:C26H29Cl4FN6O3Purity:98.73%Color and Shape:SolidMolecular weight:634.36Ref: TM-T22324
1mg66.00€2mg93.00€5mg144.00€10mg227.00€25mg464.00€50mg677.00€100mg938.00€1mL*10mM (DMSO)188.00€JNJ-38877605
CAS:JNJ-38877605 is an ATP-competitive c-Met inhibitor (IC50: 4 nM), 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases.Formula:C19H13F2N7Purity:97.04% - 98.27%Color and Shape:SolidMolecular weight:377.35EGFR-IN-8
CAS:EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLCFormula:C32H23ClF3N7O4Purity:97.45%Color and Shape:SolidMolecular weight:662.02SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formula:C27H31FN4O8Purity:98%Color and Shape:SolidMolecular weight:558.56FGFR1 inhibitor-10
CAS:FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation.Formula:C26H30F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:561.62trans-Pralsetinib
CAS:trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).Formula:C27H32FN9O2Purity:98%Color and Shape:SolidMolecular weight:533.62-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
CAS:Formula:C20H21N3O2Purity:98%Color and Shape:SolidMolecular weight:335.3996399999999IN-1130
CAS:IN-1130: ALK5 inhibitor, IC50 - 5.3 nM (Smad3), 36 nM (casein), 4.3 μM (p38α MAPK).Formula:C25H20N6OPurity:99.79%Color and Shape:SolidMolecular weight:420.47
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